Product References
Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy.
iScience
McDavid A,Laniewski N,Grier A,Gill AL,Kessler HA,Huyck H,Carbonell E,Holden-Wiltse J,Bandyopadhyay S,Carnahan J,Dylag AM,Topham DJ,Falsey AR,Caserta MT,Pryhuber GS,Gill SR,Scheible KM
MHCD0417 was used in Flow Cytometry to conclude that early exposures predict the postnatal immune-microbiota axis trajectory, placing infants at later risk for respiratory morbidity in early childhood.
Fri Apr 15 00:00:00 EDT 2022
Broadly reactive human CD4+ T cells against Enterobacteriaceae are found in the naïve repertoire and are clonally expanded in the memory repertoire.
European journal of immunology
Cassotta A,Goldstein JD,Durini G,Jarrossay D,Baggi Menozzi F,Venditti M,Russo A,Falcone M,Lanzavecchia A,Gagliardi MC,Latorre D,Sallusto F
MHCD0417 was used in Flow cytometry/Cell sorting to demonstrate that a large fraction of memory Th cell clones was broadly cross-reactive to several Enterobacteriaceae species.
Mon Mar 01 00:00:00 EST 2021
Broadly reactive human CD4+ T cells against Enterobacteriaceae are found in the naïve repertoire and are clonally expanded in the memory repertoire.
European journal of immunology
Cassotta A,Goldstein JD,Durini G,Jarrossay D,Baggi Menozzi F,Venditti M,Russo A,Falcone M,Lanzavecchia A,Gagliardi MC,Latorre D,Sallusto F
MHCD0417 was used in Flow cytometry/Cell sorting to demonstrate that a large fraction of memory Th cell clones was broadly cross-reactive to several Enterobacteriaceae species.
Mon Mar 01 00:00:00 EST 2021
Deciphering and predicting CD4+ T cell immunodominance of influenza virus hemagglutinin.
The Journal of experimental medicine
Cassotta A,Paparoditis P,Geiger R,Mettu RR,Landry SJ,Donati A,Benevento M,Foglierini M,Lewis DJM,Lanzavecchia A,Sallusto F
MHCD0417 was used in Flow cytometry/Cell sorting to show the presence of a broad repertoire of naive T cells specific for cryptic H1-HA peptides and demonstrate that antigen processing represents a major constrain determining immunodominance.
Mon Oct 05 00:00:00 EDT 2020
Deciphering and predicting CD4+ T cell immunodominance of influenza virus hemagglutinin.
The Journal of experimental medicine
Cassotta A,Paparoditis P,Geiger R,Mettu RR,Landry SJ,Donati A,Benevento M,Foglierini M,Lewis DJM,Lanzavecchia A,Sallusto F
MHCD0417 was used in Flow cytometry/Cell sorting to show the presence of a broad repertoire of naive T cells specific for cryptic H1-HA peptides and demonstrate that antigen processing represents a major constrain determining immunodominance.
Mon Oct 05 00:00:00 EDT 2020
Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature.
Cell reports. Medicine
Dhariwala MO,Karthikeyan D,Vasquez KS,Farhat S,Weckel A,Taravati K,Leitner EG,Clancy S,Pauli M,Piper ML,Cohen JN,Ashouri JF,Lowe MM,Rosenblum MD,Scharschmidt TC
MHCD0417 was used in Flow cytometry/Cell sorting to elucidate features of of human prenatal skin lymphocytes by using mass and flow cytometry.
Tue Nov 17 00:00:00 EST 2020
Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature.
Cell reports. Medicine
Dhariwala MO,Karthikeyan D,Vasquez KS,Farhat S,Weckel A,Taravati K,Leitner EG,Clancy S,Pauli M,Piper ML,Cohen JN,Ashouri JF,Lowe MM,Rosenblum MD,Scharschmidt TC
MHCD0417 was used in Flow cytometry/Cell sorting to elucidate features of of human prenatal skin lymphocytes by using mass and flow cytometry.
Tue Nov 17 00:00:00 EST 2020
CD4-Dependent Modulation of HIV-1 Entry by LY6E.
Journal of virology
Yu J,Liang C,Liu SL
MHCD0417 was used in Flow cytometry/Cell sorting to show lymphocyte antigen 6E inhibits HIV-1 entry and replication in low-CD4-expressing MDMs and Jurkat cells, while facilitating viral membrane fusion in high-CD4 expressing cells.
Mon Apr 01 00:00:00 EDT 2019
CD4-Dependent Modulation of HIV-1 Entry by LY6E.
Journal of virology
Yu J,Liang C,Liu SL
MHCD0417 was used in Flow cytometry/Cell sorting to show lymphocyte antigen 6E inhibits HIV-1 entry and replication in low-CD4-expressing MDMs and Jurkat cells, while facilitating viral membrane fusion in high-CD4 expressing cells.
Mon Apr 01 00:00:00 EDT 2019
Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.
Frontiers in immunology
D'Antoni ML,Kallianpur KJ,Premeaux TA,Corley MJ,Fujita T,Laws EI,Ogata-Arakaki D,Chow DC,Khadka VS,Shikuma CM,Ndhlovu LC
Published figure using CD4 monoclonal antibody (Product # MHCD0417) in Flow Cytometry
Tue Nov 03 00:00:00 EST 2020
RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways.
Scientific reports
Ahn R,Yan D,Chang HW,Lee K,Bhattarai S,Huang ZM,Nakamura M,Singh R,Afifi L,Taravati K,Munoz-Sandoval P,Pauli M,Rosenblum MD,Liao W
MHCD0417 was used in Flow cytometry/Cell sorting to show the molecular heterogeneity of plaque psoriasis and identify the subtype specific signalling pathways.
Fri Jul 27 00:00:00 EDT 2018
High frequency of intestinal TH17 cells correlates with microbiota alterations and disease activity in multiple sclerosis.
Science advances
Cosorich I,Dalla-Costa G,Sorini C,Ferrarese R,Messina MJ,Dolpady J,Radice E,Mariani A,Testoni PA,Canducci F,Comi G,Martinelli V,Falcone M
MHCD0417 was used in Flow cytometry/Cell sorting to assess the crucial role of the intestinal environment in promoting Th17 cell expansion in human multiple sclerosis patients.
Sat Jul 01 00:00:00 EDT 2017
DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes.
Journal of immunological methods
Hohos NM,Lee K,Ji L,Yu M,Kandasamy MM,Phillips BG,Baile CA,He C,Schmitz RJ,Meagher RB
MHCD0417 was used in Immunocytochemistry-immunoflourescence to suggest a hierarchy of responsiveness among classes of leukocytes with varying methylome response to physiological stress and disease.
Thu Sep 01 00:00:00 EDT 2016
Tumor-infiltrating Tim-3+ T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk.
Oncoimmunology
Li J,Shayan G,Avery L,Jie HB,Gildener-Leapman N,Schmitt N,Lu BF,Kane LP,Ferris RL
MHCD0417 was used in flow cytometry to study the role of PD-1 and Tim-3 crosstalk in the regulation of antitumor T cell responses
Tue Jan 12 00:00:00 EST 2021
Plasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion.
The Journal of clinical investigation
Zhang Z,Cheng L,Zhao J,Li G,Zhang L,Chen W,Nie W,Reszka-Blanco NJ,Wang FS,Su L
Published figure using CD4 monoclonal antibody (Product # MHCD0417) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Optimization of the cytokine secretion assay for human IL-2 in single and combination assays.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Deng N,Mosmann TR
MHCD0417 was used in flow cytometry to optimize detection of IL-2 from live cells
Sat Aug 01 00:00:00 EDT 2015
Select host restriction factors are associated with HIV persistence during antiretroviral therapy.
AIDS (London, England)
Abdel-Mohsen M,Wang C,Strain MC,Lada SM,Deng X,Cockerham LR,Pilcher CD,Hecht FM,Liegler T,Richman DD,Deeks SG,Pillai SK
MHCD0417 was used in flow cytometry to ascertain the impact of cell-intrinsic immunity on the latent reservoir of HIV
Fri Feb 20 00:00:00 EST 2015
Isolation and cytokine analysis of lamina propria lymphocytes from mucosal biopsies of the human colon.
Journal of immunological methods
Bowcutt R,Malter LB,Chen LA,Wolff MJ,Robertson I,Rifkin DB,Poles M,Cho I,Loke P
MHCD0417 was used in flow cytometry to analyze mucosal pinch biopsies collected predominantly during colonoscopies.
Mon Jun 01 00:00:00 EDT 2015
High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer.
Cancer research
Péguillet I,Milder M,Louis D,Vincent-Salomon A,Dorval T,Piperno-Neumann S,Scholl SM,Lantz O
MHCD0417 was used in flow cytometry to examine human differentiated effector CD4(+) T cells that are defined by low levels of IL-2 and IL-7 receptors.
Tue Apr 15 00:00:00 EDT 2014
Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice.
PLoS pathogens
Li G,Cheng M,Nunoya J,Cheng L,Guo H,Yu H,Liu YJ,Su L,Zhang L
MHCD0417 was used in flow cytometry to study the role of plasmacytoid dendritic cells in human immunodeficiency virus type 1 infection and pathogenesis
Tue Jul 01 00:00:00 EDT 2014
Highly heterogeneous, activated, and short-lived regulatory T cells during chronic filarial infection.
European journal of immunology
Metenou S,Coulibaly YI,Sturdevant D,Dolo H,Diallo AA,Soumaoro L,Coulibaly ME,Kanakabandi K,Porcella SF,Klion AD,Nutman TB
MHCD0417 was used in Flow cytometry/Cell sorting to study how in filarial infection, the expanded Treg-cell populations are heterogeneous, short-lived, activated, and express higher levels of molecules known to modulate immune responsiveness.
Tue Jul 01 00:00:00 EDT 2014
Concomitant evaluation of PMA+ionomycin-induced kinase phosphorylation and cytokine production in T cell subsets by flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Crawford TQ,Jalbert E,Ndhlovu LC,Barbour JD
Published figure using CD4 monoclonal antibody (Product # MHCD0417) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
B cell responses to HIV antigen are a potent correlate of viremia in HIV-1 infection and improve with PD-1 blockade.
PloS one
Nicholas KJ,Zern EK,Barnett L,Smith RM,Lorey SL,Copeland CA,Sadagopal S,Kalams SA
MHCD0417 was used in flow cytometry to assess the extent of B cell dysfunction during HIV infection.
Tue Sep 16 00:00:00 EDT 2014
Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination.
Vaccine
Li X,Miao H,Henn A,Topham DJ,Wu H,Zand MS,Mosmann TR
MHCD0417 was used in flow cytometry to study influenza-specific CD4 T cells respond to vaccination using Ki67 as a marker.
Fri Jun 29 00:00:00 EDT 2012
TH17, TH22 and Treg cells are enriched in the healthy human cecum.
PloS one
Wolff MJ,Leung JM,Davenport M,Poles MA,Cho I,Loke P
Published figure using CD4 monoclonal antibody (Product # MHCD0417) in Flow Cytometry
Fri Dec 07 00:00:00 EST 2012
Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes.
Diabetes
Hughson A,Bromberg I,Johnson B,Quataert S,Jospe N,Fowell DJ
MHCD0417 was used in Flow cytometry/Cell sorting to determine the relative proportions of effector and regulatory T cells in the CD4+CD25+Foxp3+ T-cell compartment in varying type 1 diabetes disease states.
Mon Aug 01 00:00:00 EDT 2011
HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses.
Journal of virology
Crawford TQ,Ndhlovu LC,Tan A,Carvidi A,Hecht FM,Sinclair E,Barbour JD
MHCD0417 was used in flow cytometry to elucidate relationships among MAPK pathway function, HIV-1-induced activation, and exhaustion markers in circulating CD8+ T cells
Thu Dec 01 00:00:00 EST 2011
CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses.
Vaccine
Scheible K,Zhang G,Baer J,Azadniv M,Lambert K,Pryhuber G,Treanor JJ,Topham DJ
MHCD0417 was used in flow cytometry to examine human cross-reactive T cells against a pandemic virus.
Thu Mar 03 00:00:00 EST 2011
Peripheral immature CD2-/low T cell development from type 2 to type 1 cytokine production.
Journal of immunology (Baltimore, Md. : 1950)
Loza MJ,Perussia B
MHCD0417 was used in flow cytometry to identify and characterize immature CD2(-/low) T cells in peripheral blood.
Sun Sep 15 00:00:00 EDT 2002
