Product References
Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2.
eLife
Tsyklauri O,Chadimova T,Niederlova V,Kovarova J,Michalik J,Malatova I,Janusova S,Ivashchenko O,Rossez H,Drobek A,Vecerova H,Galati V,Kovar M,Stepanek O
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Flow Cytometry
Fri Jan 27 00:00:00 EST 2023
Splenic NKG2D confers resilience versus susceptibility in mice after chronic social defeat stress: beneficial effects of (R)-ketamine.
European archives of psychiatry and clinical neuroscience
Zhang K,Sakamoto A,Chang L,Qu Y,Wang S,Pu Y,Tan Y,Wang X,Fujita Y,Ishima T,Hatano M,Hashimoto K
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells.
World journal of gastroenterology
Han QJ,Mu YL,Zhao HJ,Zhao RR,Guo QJ,Su YH,Zhang J
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice.
Frontiers in immunology
Prasad M,Wojciech L,Brzostek J,Hu J,Chua YL,Tung DWH,Yap J,Rybakin V,Gascoigne NRJ
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Flow Cytometry
Thu Sep 23 00:00:00 EDT 2021
Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions.
Frontiers in immunology
Sanz-Ortega L,Rojas JM,Portilla Y,Pérez-Yagüe S,Barber DF
16-5882-82 was used in Flow Cytometry to provide further support for using MNPs in combination with EMFs to favor specific retention of functional NK cells in a region of interest, which may prove beneficial to adoptive cell-therapy protocols.
Tue Sep 29 00:00:00 EDT 2020
DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.
Nature medicine
Xiao Q,Wu J,Wang WJ,Chen S,Zheng Y,Yu X,Meeth K,Sahraei M,Bothwell ALM,Chen L,Bosenberg M,Chen J,Sexl V,Sun L,Li L,Tang W,Wu D
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
The Journal of allergy and clinical immunology
Bloodworth MH,Rusznak M,Pfister CC,Zhang J,Bastarache L,Calvillo SA,Chappell JD,Boyd KL,Toki S,Newcomb DC,Stier MT,Zhou W,Goleniewska K,Moore ML,Hartert TV,Niswender KD,Peebles RS
16-5882 was used in Flow cytometry/Cell sorting to investigate the effect of activating the GLP-1R signalling pathway on mice mimicking severe respiratory infection.
Wed Aug 01 00:00:00 EDT 2018
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity.
The Journal of investigative dermatology
Nielsen MM,Dyring-Andersen B,Schmidt JD,Witherden D,Lovato P,Woetmann A,Ødum N,Poulsen SS,Havran WL,Geisler C,Bonefeld CM
16-5882 was used in Blocking experiments to investigate the role of NKG2D in contact hypersensitivity.
Fri May 01 00:00:00 EDT 2015
NKp46+ Innate Lymphoid Cells Dampen Vaginal CD8 T Cell Responses following Local Immunization with a Cholera Toxin-Based Vaccine.
PloS one
Luci C,Bekri S,Bihl F,Pini J,Bourdely P,Nouhen K,Malgogne A,Walzer T,Braud VM,Anjuère F
16-5882 was used in Flow cytometry/Cell sorting to show that vaginal NKp46+ Innate lymphoid cells dampen vaccine-induced CD8 T cell responses generated after local immunization with a Cholera Toxin-Based Vaccine.
Thu Jun 23 00:00:00 EDT 2016
Depletion of B220+NK1.1+ cells enhances the rejection of established melanoma by tumor-specific CD4+ T cells.
Oncoimmunology
Wilson KA,Goding SR,Neely HR,Harris KM,Antony PA
16-5882 was used in Flow cytometry/Cell sorting to show that interferon-producing killer dendritic cells are an important inhibitor of the CD4(+) T cell response to melanoma.
Sat Aug 01 00:00:00 EDT 2015
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.
Nature medicine
Xing L,Dai Z,Jabbari A,Cerise JE,Higgins CA,Gong W,de Jong A,Harel S,DeStefano GM,Rothman L,Singh P,Petukhova L,Mackay-Wiggan J,Christiano AM,Clynes R
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
A gluten-free diet lowers NKG2D and ligand expression in BALB/c and non-obese diabetic (NOD) mice.
Clinical and experimental immunology
Adlercreutz EH,Weile C,Larsen J,Engkilde K,Agardh D,Buschard K,Antvorskov JC
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Immunohistochemistry
Fri Aug 01 00:00:00 EDT 2014
A gluten-free diet lowers NKG2D and ligand expression in BALB/c and non-obese diabetic (NOD) mice.
Clinical and experimental immunology
Adlercreutz EH,Weile C,Larsen J,Engkilde K,Agardh D,Buschard K,Antvorskov JC
Published figure using CD314 (NKG2D) monoclonal antibody (Product # 16-5882-82) in Immunohistochemistry
Fri Aug 01 00:00:00 EDT 2014
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells.
eLife
Sojka DK,Plougastel-Douglas B,Yang L,Pak-Wittel MA,Artyomov MN,Ivanova Y,Zhong C,Chase JM,Rothman PB,Yu J,Riley JK,Zhu J,Tian Z,Yokoyama WM
16-5882 was used in Flow cytometry/Cell sorting to investigate whether tissue-resident and cells resembling conventional splenic natural killer cells natural killer cells are derived from the same lineage, showing that there are at least four distinct lineages.
Wed Jan 01 00:00:00 EST 2014
Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells.
Nature immunology
Cohen NR,Brennan PJ,Shay T,Watts GF,Brigl M,Kang J,Brenner MB
16-5882 was used in Flow cytometry/Cell sorting to profile gene expression in invariant natural killer T cells during ontogeny and in peripheral subsets.
Tue Jan 01 00:00:00 EST 2013
Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor.
Proceedings of the National Academy of Sciences of the United States of America
Shin JH,Zhang L,Murillo-Sauca O,Kim J,Kohrt HE,Bui JD,Sunwoo JB
16-5882 was used in Flow cytometry/Cell sorting to explore the regulation of natural killer cells by the aryl hydrocarbon receptor (AhR).
Tue Jul 23 00:00:00 EDT 2013
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity.
Proceedings of the National Academy of Sciences of the United States of America
Lang PA,Lang KS,Xu HC,Grusdat M,Parish IA,Recher M,Elford AR,Dhanji S,Shaabani N,Tran CW,Dissanayake D,Rahbar R,Ghazarian M,Brüstle A,Fine J,Chen P,Weaver CT,Klose C,Diefenbach A,Häussinger D,Carlyle JR,Kaech SM,Mak TW,Ohashi PS
16-5882 was used in Blocking experiments to identify an important role of regulatory NK cells in limiting T-cell immunity during virus infection.
Tue Jan 24 00:00:00 EST 2012
Direct recognition of Fusobacterium nucleatum by the NK cell natural cytotoxicity receptor NKp46 aggravates periodontal disease.
PLoS pathogens
Chaushu S,Wilensky A,Gur C,Shapira L,Elboim M,Halftek G,Polak D,Achdout H,Bachrach G,Mandelboim O
16-5882 was used in Flow cytometry/Cell sorting to provide the first evidence that NCR1 and NKp46 directly recognize a periodontal pathogen.
Mon Jul 09 00:00:00 EDT 2012
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance.
Oncoimmunology
Mizutani T,Neugebauer N,Putz EM,Moritz N,Simma O,Zebedin-Brandl E,Gotthardt D,Warsch W,Eckelhart E,Kantner HP,Kalinke U,Lienenklaus S,Weiss S,Strobl B,Müller M,Sexl V,Stoiber D
16-5882 was used in Flow cytometry/Cell sorting to examine the role of Type 1 IFN signalling in the prevention of leukaemogenesis.
Mon Oct 01 00:00:00 EDT 2012
A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.
Blood
Eckelhart E,Warsch W,Zebedin E,Simma O,Stoiber D,Kolbe T,Rülicke T,Mueller M,Casanova E,Sexl V
16-5882 was used in Flow cytometry/Cell sorting to develop a novel mouse line to delineate the essential and cell-intrinsic role of STAT5 in NK-cell development.
Thu Feb 03 00:00:00 EST 2011
Natural killer cells recognize friend retrovirus-infected erythroid progenitor cells through NKG2D-RAE-1 interactions In Vivo.
Journal of virology
Ogawa T,Tsuji-Kawahara S,Yuasa T,Kinoshita S,Chikaishi T,Takamura S,Matsumura H,Seya T,Saga T,Miyazawa M
16-5882 was used in Blocking experiments to demonstrate a correlation between the expression of the products of RAE-1 genes in target cells and their susceptibility to killing by NK cells from FV-infected animals.
Wed Jun 01 00:00:00 EDT 2011
The requirement for NKG2D in NK cell-mediated rejection of parental bone marrow grafts is determined by MHC class I expressed by the graft recipient.
Blood
Beilke JN,Benjamin J,Lanier LL
16-5882 was used in Immuno-assay to show that natural killer G2D (NKG2D) rejection depends upon on the major histocompatibility complex haplotype of the donor cells.
Thu Dec 09 00:00:00 EST 2010
Latent herpesvirus infection arms NK cells.
Blood
White DW,Keppel CR,Schneider SE,Reese TA,Coder J,Payton JE,Ley TJ,Virgin HW,Fehniger TA
16-5882 was used in Flow cytometry/Cell sorting to investigate the immune environment created by latent herpesvirus infection, and how this may provide a mechanism whereby host NK-cell function is enhanced in vivo..
Thu Jun 03 00:00:00 EDT 2010
MHC class I-deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I-sufficient environment.
The Journal of experimental medicine
Elliott JM,Wahle JA,Yokoyama WM
16-5882 was used in Flow cytometry/Cell sorting to investigate whether licensing is developmentally determined in the bone marrow, showing that MHC class I ligands are not absolutely required for licensing.
Mon Sep 27 00:00:00 EDT 2010
Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma.
The Journal of experimental medicine
Xie Y,Akpinarli A,Maris C,Hipkiss EL,Lane M,Kwon EK,Muranski P,Restifo NP,Antony PA
16-5882 was used in Flow cytometry/Cell sorting to study the regression of tumours due to naive tumor-specific CD4(+) T cell differentiation.
Mon Mar 15 00:00:00 EDT 2010
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease.
The Journal of clinical investigation
Borchers MT,Wesselkamper SC,Curull V,Ramirez-Sarmiento A,Sánchez-Font A,Garcia-Aymerich J,Coronell C,Lloreta J,Agusti AG,Gea J,Howington JA,Reed MF,Starnes SL,Harris NL,Vitucci M,Eppert BL,Motz GT,Fogel K,McGraw DW,Tichelaar JW,Orozco-Levi M
16-5882 was used in Blocking experiments to study the involvement of the CTL activation receptor, NK cell group 2D, in the development of chronic obstructive pulmonary disorder.
Sun Mar 01 00:00:00 EST 2009
Ly49H signaling through DAP10 is essential for optimal natural killer cell responses to mouse cytomegalovirus infection.
The Journal of experimental medicine
Orr MT,Sun JC,Hesslein DG,Arase H,Phillips JH,Takai T,Lanier LL
16-5882 was used in Functional assays to demonstrate that optimal NK cell-mediated immunity to MCMV depends on Ly49H signalling through both DAP10 and DAP12.
Mon Apr 13 00:00:00 EDT 2009
Migratory and antigen presentation functions of IFN-producing killer dendritic cells.
Cancer research
Himoudi N,Yan M,Bouma G,Morgenstern D,Wallace R,Seddon B,Buddle J,Eddaoudi A,Howe SJ,Cooper N,Anderson J
16-5882 was used in Flow cytometry/Cell sorting to study how BM-IKDCs are capable of cytotoxic killing of tumour targets, and also of potent antigen presentation after encountering antigen in the context of a viable target cell.
Sat Aug 15 00:00:00 EDT 2009
Cytokine-induced memory-like natural killer cells.
Proceedings of the National Academy of Sciences of the United States of America
Cooper MA,Elliott JM,Keyel PA,Yang L,Carrero JA,Yokoyama WM
16-5882 was used in Flow cytometry/Cell sorting to identify an ability of innate immune cells to retain an intrinsic memory of prior activation.
Tue Feb 10 00:00:00 EST 2009
The innate immune system recognizes and regulates major histocompatibility complex class I (MHCI) expression on MHCIlow tumor cells.
Cancer immunity
Rubin B,Riond J,Courtiade L,Roullet N,Gairin JE
16-5882 was used in Blocking experiments to investigate the interaction of normal spleen cells with tumour cells expressing low levels of MHCI on the cell surface.
Thu Sep 11 00:00:00 EDT 2008
An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.
The Journal of experimental medicine
Cho JH,Boyman O,Kim HO,Hahm B,Rubinstein MP,Ramsey C,Kim DM,Surh CD,Sprent J
16-5882 was used in Flow cytometry/Cell sorting to describe a novel form of homeostatic proliferation that occurs when naive T cells encounter raised levels of IL-2 and IL-15 in vivo.
Mon Aug 06 00:00:00 EDT 2007
ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15.
Blood
Sutherland CL,Rabinovich B,Chalupny NJ,Brawand P,Miller R,Cosman D
16-5882 was used in Functional assays to demonstrate that ULBP expression can elicit a potent immune response and suggest that ULBPs, alone or in combination with IL-15, can be exploited for antitumor therapy.
Tue Aug 15 00:00:00 EDT 2006
The NKG2D-activating receptor mediates pulmonary clearance of Pseudomonas aeruginosa.
Infection and immunity
Borchers MT,Harris NL,Wesselkamper SC,Zhang S,Chen Y,Young L,Lau GW
16-5882 was used in Blocking experiments to demonstrate the importance of NKG2D-mediated immune activation in the clearance of acute bacterial infection.
Mon May 01 00:00:00 EDT 2006
