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Immunogen sequence: FQNSKFQRDL VTLRTDFSNF TSNTVAEIQA LTSQGSSLEE TIASLKAEVE GFKQERQAGV SELQEHTTQK AHLGHCPHCP SVCVPVHSEM LLRVQQLVQD LKKLTCQVAT LNNNASTEGT C; Positive Samples: U-87MG, K-562, Raji, Mouse testis; Cellular Location: Membrane, Single-pass type II membrane protein
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Protein Aliases: C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived); C-type lectin domain family 10 member A; C-type lectin domain family 10, member A; C-type lectin superfamily member 14; CD301; M-ASGP-BP-1; Macrophage asialoglycoprotein-binding protein 1; macrophage galactose N-acetyl-galactosamine specific lectin 1; Macrophage galactose/N-acetylgalactosamine-specific lectin; Macrophage lectin 2; macrophage lectin 2 (calcium dependent); MMGL
Gene Aliases: CD301; CD301a; CLEC10A; CLECSF13; CLECSF14; HML; HML2; M-ASGP-BP-1; MGL; Mgl1
UniProt ID: (Human) A8K8J8, (Mouse) P49300
Entrez Gene ID: (Human) 10462, (Mouse) 17312
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