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This antibody detects human CLEC10A/CD301 in direct ELISAs and Western blots and mouse CLEC10A in Western blots. Less than 1% cross-reactivity with recombinant human (rh) CLEC1, rhCLEC2, and rhCLEC3B is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived); C-type lectin domain family 10 member A; C-type lectin domain family 10, member A; C-type lectin superfamily member 14; CD301; M-ASGP-BP-1; Macrophage asialoglycoprotein-binding protein 1; macrophage galactose N-acetyl-galactosamine specific lectin 1; Macrophage galactose/N-acetylgalactosamine-specific lectin; Macrophage lectin 2; macrophage lectin 2 (calcium dependent); MMGL
Gene Aliases: CD301; CD301a; CLEC10A; CLECSF13; CLECSF14; HML; HML2; M-ASGP-BP-1; MGL; Mgl1
UniProt ID: (Human) A8K8J8, (Mouse) P49300
Entrez Gene ID: (Human) 10462, (Mouse) 17312
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