Product References
Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.
Nature communications
Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer.
International journal of molecular sciences
Huntington KE,Louie AD,Srinivasan PR,Schorl C,Lu S,Silverberg D,Newhouse D,Wu Z,Zhou L,Borden BA,Giles FJ,Dooner M,Carneiro BA,El-Deiry WS
11-0271-82 was used in Flow cytometry/Cell sorting to investigate the immunomodulatory properties of the GSK-3 inhibitor elraglusib, revealing its capacity to enhance immune cell-mediated tumor cell killing, sensitize colorectal cancer cells to immune-mediated cytotoxicity, reduce immunosuppressive factors, and improve survival when combined with immune checkpoint blockade therapy in preclinical models and clinical samples.
Thu Jun 29 00:00:00 EDT 2023
The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function.
eLife
Li S,Bern MD,Miao B,Fan C,Xing X,Inoue T,Piersma SJ,Wang T,Colonna M,Kurosaki T,Yokoyama WM
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Mon Oct 03 00:00:00 EDT 2022
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Effect of Subcutaneous Anti-CD20 Antibody-Mediated B Cell Depletion on Susceptibility to Pneumocystis Infection in Mice.
mSphere
Dai G,Noell K,Weckbecker G,Kolls JK
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Wed May 05 00:00:00 EDT 2021
Effect of Subcutaneous Anti-CD20 Antibody-Mediated B Cell Depletion on Susceptibility to Pneumocystis Infection in Mice.
mSphere
Dai G,Noell K,Weckbecker G,Kolls JK
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Wed May 05 00:00:00 EDT 2021
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell reports
Seydoux E,Wan YH,Feng J,Wall A,Aljedani S,Homad LJ,MacCamy AJ,Weidle C,Gray MD,Brumage L,Taylor JJ,Pancera M,Stamatatos L,McGuire AT
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.
Cell reports
Chen ELY,Lee CR,Thompson PK,Wiest DL,Anderson MK,Zúñiga-Pflücker JC
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Combination blockade of KLRG1 and PD-1 promotes immune control of local and disseminated cancers.
Oncoimmunology
Tata A,Dodard G,Fugère C,Leget C,Ors M,Rossi B,Vivier E,Brossay L
11-0271-82 was used in Flow Cytometry to demonstrate if killer cell lectin-like receptor G1 is a novel checkpoint inhibitor target that affects NK and T cell anti-tumor immunity.
Tue Jun 15 00:00:00 EDT 2021
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Mon May 31 00:00:00 EDT 2021
Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells.
Cell reports
Dodard G,Tata A,Erick TK,Jaime D,Miah SMS,Quatrini L,Escalière B,Ugolini S,Vivier E,Brossay L
11-0271 was used in Flow cytometry/Cell sorting to characterize the kinetics and immune response of each of the hepatic NK cell populations to viral challenge and other stimuli.
Tue Jul 07 00:00:00 EDT 2020
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Cell
Jin C,Lagoudas GK,Zhao C,Bullman S,Bhutkar A,Hu B,Ameh S,Sandel D,Liang XS,Mazzilli S,Whary MT,Meyerson M,Germain R,Blainey PC,Fox JG,Jacks T
11-0271 was used in Flow cytometry/Cell sorting to link local microbiota-immune crosstalk to lung tumor development and thereby define key cellular and molecular mediators that may serve as effective targets in lung cancer intervention.
Thu Feb 21 00:00:00 EST 2019
miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival.
Cell reports
Gagnon JD,Kageyama R,Shehata HM,Fassett MS,Mar DJ,Wigton EJ,Johansson K,Litterman AJ,Odorizzi P,Simeonov D,Laidlaw BJ,Panduro M,Patel S,Jeker LT,Feeney ME,McManus MT,Marson A,Matloubian M,Sanjabi S,Ansel KM
11-0271-82 was used in Flow Cytometry to show that miR-15/16 restrict T cell cycle, survival, and memory T cell differentiation.
Tue Aug 20 00:00:00 EDT 2019
DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.
Nature medicine
Xiao Q,Wu J,Wang WJ,Chen S,Zheng Y,Yu X,Meeth K,Sahraei M,Bothwell ALM,Chen L,Bosenberg M,Chen J,Sexl V,Sun L,Li L,Tang W,Wu D
11-0271 was used in Flow Cytometry to identify a novel tumour immune-suppressive mechanism and immunotherapeutic targets particularly relevant for colorectal cancers and a subset of melanomas.
Thu Mar 01 00:00:00 EST 2018
BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data.
Genome medicine
Upadhyay AA,Kauffman RC,Wolabaugh AN,Cho A,Patel NB,Reiss SM,Havenar-Daughton C,Dawoud RA,Tharp GK,Sanz I,Pulendran B,Crotty S,Lee FE,Wrammert J,Bosinger SE
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Tue Mar 20 00:00:00 EDT 2018
Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function.
Nature communications
Wang F,Meng M,Mo B,Yang Y,Ji Y,Huang P,Lai W,Pan X,You T,Luo H,Guan X,Deng Y,Yuan S,Chu J,Namaka M,Hughes T,Ye L,Yu J,Li X,Deng Y
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Mon Nov 19 00:00:00 EST 2018
Phenotypic characterization of regulatory T cells from antiretroviral-naive HIV-1-infected people.
Immunology
Ambada GN,Ntsama CE,Nji NN,Ngu LN,Sake CN,Lissom A,Tchouangeu FT,Tchadji J,Sosso M,Etoa FX,Nchinda GW
11-0271 was used in Flow cytometry/Cell sorting to determine how antiretroviral therapy-naive HIV-1 infection affects the phenotypic properties of Treg cells.
Tue Aug 01 00:00:00 EDT 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD27 monoclonal antibody (Product # 11-0271-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population.
Oncotarget
Wu CC,Liu SJ,Chen HW,Shen KY,Leng CH
11-0271 was used in Flow cytometry/Cell sorting to explore the use of TLR2 agonist-fused antigens for efficient cancer therapy.
Tue May 24 00:00:00 EDT 2016
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
11-0271 was used in Flow cytometry/Cell sorting to that Treg cell-derived IL-10 is needed to insulate, and promote the quality of, developing CD8(+) T cells.
Sat Aug 01 00:00:00 EDT 2015
Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.
PLoS neglected tropical diseases
Katawa G,Layland LE,Debrah AY,von Horn C,Batsa L,Kwarteng A,Arriens S,W Taylor D,Specht S,Hoerauf A,Adjobimey T
11-0271 was used in Flow cytometry/Cell sorting to provide initial evidence that elevated frequencies of Th17 and Th2 cells form part of the immune network instigating the development of severe onchocerciasis.
Thu Jan 01 00:00:00 EST 2015
Identification and characterization of latency-associated peptide-expressing γδ T cells.
Nature communications
Rezende RM,da Cunha AP,Kuhn C,Rubino S,M'Hamdi H,Gabriely G,Vandeventer T,Liu S,Cialic R,Pinheiro-Rosa N,Oliveira RP,Gaublomme JT,Obholzer N,Kozubek J,Pochet N,Faria AMC,Weiner HL
11-0271 was used in Flow cytometry/Cell sorting to describe a subset of regulatory γδ T cells that express the latency-associated peptide, a membrane-bound TGF-β1.
Tue Dec 08 00:00:00 EST 2015
Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells.
Journal of the American Society of Nephrology : JASN
Cherukuri A,Rothstein DM,Clark B,Carter CR,Davison A,Hernandez-Fuentes M,Hewitt E,Salama AD,Baker RJ
11-0271 was used in Flow cytometry/Cell sorting to explore proinflammatory cytokine expression in B-cell subsets.
Tue Jul 01 00:00:00 EDT 2014
MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling.
Nature communications
Kieckbusch J,Gaynor LM,Moffett A,Colucci F
11-0271 was used in Flow cytometry/Cell sorting to investigate MHC-dependent NK inhibition as a risk factor for pregnancy-related complications associated with impaired arterial remodelling.
Fri Feb 28 00:00:00 EST 2014
Bortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myeloma.
PloS one
Stessman HA,Mansoor A,Zhan F,Linden MA,Van Ness B,Baughn LB
11-0271 was used in Flow cytometry/Cell sorting to suggest a novel therapeutic approach for reversing Bz resistance in refractory multiple myeloma.
Tue Aug 05 00:00:00 EDT 2014
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Nature medicine
Alvarez-Breckenridge CA,Yu J,Price R,Wojton J,Pradarelli J,Mao H,Wei M,Wang Y,He S,Hardcastle J,Fernandez SA,Kaur B,Lawler SE,Vivier E,Mandelboim O,Moretta A,Caligiuri MA,Chiocca EA
11-0271 was used in Flow cytometry/Cell sorting to demonstrate that glioblastoma virotherapy is limited partially by an antiviral NK cell response involving specific NCRs, uncovering new potential targets to enhance cancer virotherapy.
Sat Dec 01 00:00:00 EST 2012
γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response.
Immunity
Zeng X,Wei YL,Huang J,Newell EW,Yu H,Kidd BA,Kuhns MS,Waters RW,Davis MM,Weaver CT,Chien YH
11-0271 was used in Flow cytometry/Cell sorting to study the γδ T cell response to the algae protein, phycoerythrin.
Fri Sep 21 00:00:00 EDT 2012
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance.
Oncoimmunology
Mizutani T,Neugebauer N,Putz EM,Moritz N,Simma O,Zebedin-Brandl E,Gotthardt D,Warsch W,Eckelhart E,Kantner HP,Kalinke U,Lienenklaus S,Weiss S,Strobl B,Müller M,Sexl V,Stoiber D
11-0271 was used in Flow cytometry/Cell sorting to examine the role of Type 1 IFN signalling in the prevention of leukaemogenesis.
Mon Oct 01 00:00:00 EDT 2012
Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A.
Journal of virology
Sridhar S,Reyes-Sandoval A,Draper SJ,Moore AC,Gilbert SC,Gao GP,Wilson JM,Hill AV
11-0271 was used in Flow cytometry/Cell sorting to compare efficacy of AdH5 and AdC6 vector vaccines expressing antigen under HCMV promotion.
Tue Apr 01 00:00:00 EDT 2008
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling.
Genes & development
Taghon TN,David ES,Zúñiga-Pflücker JC,Rothenberg EV
11-0271 was used in Flow cytometry/Cell sorting to study how Notch/Delta signaling is not sufficient for T-lineage specification and commitment, but can be permissive for the maintenance and proliferation of uncommitted progenitors.
Fri Apr 15 00:00:00 EDT 2005
Characterization of murine CD70, the ligand of the TNF receptor family member CD27.
Journal of immunology (Baltimore, Md. : 1950)
Tesselaar K,Gravestein LA,van Schijndel GM,Borst J,van Lier RA
Sat Nov 15 00:00:00 EST 1997
