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Product Details
16337-1-AP
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Product Specific Information
Immunogen sequence: SAHLRDIFL GRCAEYRALL SPEQRNKNCT AIWEAFKVAL DKDPCSVLPS DYDLFINLSR HSIPRDKSLF WENSHLLVNS FADNTRRFMP LSDVLYGRVA DFLSWCRQKN DSGLDYQSCP TSEDCENNPV DSFWKRASIQ YSKDSSGVIH VMLNGSEPTG AYPIKGFFAD YEIPNLQKEK ITRIEIWVMH EIGGPNVESC GEGSMKVLEK RLKDMGFQYS CINDYRPVKL LQCVDHSTHP DCALKSAAAA TQRKAPSLYT EQRAGLIIPL FLVLASRTQL (40-318 aa encoded by BC012095)
Target Information
Bone marrow stromal cell antigen 1 (BST1) is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B cell growth. BST1, which is also known as ADP-rybosyl cyclase 2 and DAMP-1, is an enzyme which is expressed by BST1 gene in human. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ADP-ribosyl cyclase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; Antigen BP3; Bone marrow stromal antigen 1; Bone marrow stromal cell antigen 1; BP-3 alloantigen; BST-1; cADPR hydrolase 2; CD157; CD157 antigen; Cyclic ADP-ribose hydrolase 2; Leukocyte antigen 65; Ly-65; NAD(+) nucleosidase; NAD+ nucleosidase
Gene Aliases: 114/A10; A530073F09; BP-3; Bp3; BST1; Bsta1; CD157; Ly65
UniProt ID: (Human) Q10588, (Mouse) Q64277
Entrez Gene ID: (Human) 683, (Mouse) 12182
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