Product References
Laxative effect of Wenyang Yiqi Decoction on loperamide-induced astriction model mice.
Annals of translational medicine
Su Y,Zhu R,Pang C,He Z,Wu B,Wang X
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Western Blot
Tue Feb 28 00:00:00 EST 2023
Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening.
Proceedings of the National Academy of Sciences of the United States of America
Griffin KH,Thorpe SW,Sebastian A,Hum NR,Coonan TP,Sagheb IS,Loots GG,Randall RL,Leach JK
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Tue Sep 26 00:00:00 EDT 2023
Landscape of mast cell populations across organs in mice and humans.
The Journal of experimental medicine
Tauber M,Basso L,Martin J,Bostan L,Pinto MM,Thierry GR,Houmadi R,Serhan N,Loste A,Blériot C,Kamphuis JBJ,Grujic M,Kjellén L,Pejler G,Paul C,Dong X,Galli SJ,Reber LL,Ginhoux F,Bajenoff M,Gentek R,Gaudenzio N
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Mon Oct 02 00:00:00 EDT 2023
Morphology of migrating telocytes and their potential role in stem cell differentiation during cartilage development in catfish (Clarias gariepinus).
Microscopy research and technique
Abd-Elhafeez HH,Rutland CS,Soliman SA
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunohistochemistry (Paraffin)
Fri Sep 01 00:00:00 EDT 2023
Two distinctive types of telocytes in gills of fish: A light, immunohistochemical and ultra-structure study.
Microscopy research and technique
Soliman SA,Sobh A,Ali LA,Abd-Elhafeez HH
14-1172-82 was used in Immunohistochemistry to provide evidence for TCs' heterocontact with lamellar blood capillaries, the blood vessels, chloride cells, and immune cells, such as rodlet cells and lymphocytes.
Tue Nov 01 00:00:00 EDT 2022
Effects of Xiao Chengqi Formula on Slow Transit Constipation by Assessing Gut Microbiota and Metabolomics Analysis in vitro and in vivo.
Frontiers in pharmacology
Zhou Q,Zhang D,Zhang H,Wan X,Hu B,Zou Q,Su D,Peng H,Huang D,Ren D
14-1172-82 was used in Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot to show a significant decrease in the abundance of Roseburia spp.
Wed Nov 29 00:00:00 EST 2023
Lineage Tracing of FOXL1+ Cells in the Tunica Muscularis Suggests Mutual Origin for Telocytes and Smooth Muscle Cells.
Life (Basel, Switzerland)
Shushan M,Shoshkes-Carmel M
14-1172-82 was used in Immunohistochemistry-immunofluorescence to suggest a mutual origin for telocytes and smooth muscle cells.
Wed Jan 26 00:00:00 EST 2022
The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression.
Cell death & disease
Gentle IE,Moelter I,Badr MT,Döhner K,Lübbert M,Häcker G
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells.
Nature communications
Zhao R,Zuo Q,Yuan X,Jin K,Jin J,Ding Y,Zhang C,Li T,Jiang J,Li J,Zhang M,Shi X,Sun H,Zhang Y,Xu Q,Chang G,Zhao Z,Li B,Wu X,Zhang Y,Song J,Chen G,Li B
14-1172-82 was used in Flow cytometry/Cell sorting to demonstrate the feasibility of avian cloning from somatic cells.
Thu May 20 00:00:00 EDT 2021
The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.
Haematologica
Brown A,Schuetz D,Han Y,Daria D,Nattamai KJ,Eiwen K,Sakk V,Pospiech J,Saller T,van Zant G,Wagner W,Geiger H
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Tue Apr 27 00:00:00 EDT 2021
Transcriptome Sequencing and Comparative Analysis of Amphoteric ESCs and PGCs in Chicken (Gallus gallus).
Animals : an open access journal from MDPI
Jin K,Zhou J,Zuo Q,Song J,Zhang Y,Chang G,Chen G,Li B
14-1172 was used in Flow cytometry/Cell sorting to determine the sex of collected chicken (Gallus gallus) pluripotent embryonic stem cells (ESCs) and primordial germ cells (PGCs)by identifying specific sex markers via polymerase chain reaction (PCR) and fluorescence activated cell sorter (FACS).
Fri Nov 27 00:00:00 EST 2020
Morphological and immunohistochemical phenotype of TCs in the intestinal bulb of Grass carp and their potential role in intestinal immunity.
Scientific reports
Abd-Elhafeez HH,Abou-Elhamd AS,Soliman SA
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunohistochemistry
Thu Aug 20 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Inhibition of FGF2-Mediated Signaling in GIST-Promising Approach for Overcoming Resistance to Imatinib.
Cancers
Boichuk S,Galembikova A,Mikheeva E,Bikinieva F,Aukhadieva A,Dunaev P,Khalikov D,Petrov S,Kurtasanov R,Valeeva E,Kireev I,Dugina V,Lushnikova A,Novikova M,Kopnin P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunohistochemistry
Wed Jun 24 00:00:00 EDT 2020
Inhibition of FGF2-Mediated Signaling in GIST-Promising Approach for Overcoming Resistance to Imatinib.
Cancers
Boichuk S,Galembikova A,Mikheeva E,Bikinieva F,Aukhadieva A,Dunaev P,Khalikov D,Petrov S,Kurtasanov R,Valeeva E,Kireev I,Dugina V,Lushnikova A,Novikova M,Kopnin P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunohistochemistry
Wed Jun 24 00:00:00 EDT 2020
Fish telocytes and their relation to rodlet cells in ruby-red-fin shark (rainbow shark) Epalzeorhynchos frenatum (Teleostei: Cyprinidae).
Scientific reports
Abd-Elhafeez HH,Abdo W,Kamal BM,Soliman SA
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunohistochemistry
Tue Nov 03 00:00:00 EST 2020
C1EIP Functions as an Activator of ENO1 to Promote Chicken PGCs Formation via Inhibition of the Notch Signaling Pathway.
Frontiers in genetics
Jin K,Li D,Jin J,Song J,Zhang Y,Chang G,Chen G,Li B
14-1172-85 was used in Immunocytochemistry, Flow Cytometry to report a PGC-related marker gene: C1EIP (Chromosome 1 Expression in PGCs), whose activation and expression are regulated by the transcription factor STAT3 (signal transducer and activator of transcription 3), histone acetylation, and promoter methylation. C1EIP regulates PGCs formation by mediating the expression of PGC-associated genes, such as CVH (Chicken Vasa Homologous) and CKIT (Chicken KIT proto-oncogene).
Mon Sep 28 00:00:00 EDT 2020
C1EIP Functions as an Activator of ENO1 to Promote Chicken PGCs Formation via Inhibition of the Notch Signaling Pathway.
Frontiers in genetics
Jin K,Li D,Jin J,Song J,Zhang Y,Chang G,Chen G,Li B
14-1172-85 was used in Immunocytochemistry, Flow Cytometry to report a PGC-related marker gene: C1EIP (Chromosome 1 Expression in PGCs), whose activation and expression are regulated by the transcription factor STAT3 (signal transducer and activator of transcription 3), histone acetylation, and promoter methylation. C1EIP regulates PGCs formation by mediating the expression of PGC-associated genes, such as CVH (Chicken Vasa Homologous) and CKIT (Chicken KIT proto-oncogene).
Mon Sep 28 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2021
Effects of Lactobacillus plantarum CQPC01-fermented soybean milk on activated carbon-induced constipation through its antioxidant activity in mice.
Food science & nutrition
Liu B,Xiao X,Zhou X,Zhou J,Lan L,Long X,Pan Y,Du M,Zhao X
14-1172-82 was used in Western Blot to show LP-CQPC01 could be used as a new starter to produce high-quality soybean milk, which might be used as a functional drink.
Sat Jun 01 00:00:00 EDT 2019
Preventive Effects of Different Fermentation Times of Shuidouchi on Diphenoxylate-Induced Constipation in Mice.
Foods (Basel, Switzerland)
Chen L,Zhang J,Suo H,Wang W,Wang H,Zhang Y,Hu Q,Zhao X,Li J
14-1172-82 was used in Western Blot to compare the prevention effects of Shuidouchi with different fermentation times on constipation in mice.
Fri Mar 01 00:00:00 EST 2019
Interstitial cell network volume is reduced in the terminal bowel of ageing mice.
Journal of cellular and molecular medicine
Gamage PPKM,Patel BA,Yeoman MS,Ranson RN,Saffrey MJ
14-1172 was used in Immunohistochemistry to suggest that ageing is associated with a reduction in the network volume of ICC in the terminal GI tract, which may influence the normal function of these regions.
Mon Oct 01 00:00:00 EDT 2018
Hsd3b2 associated in modulating steroid hormone synthesis pathway regulates the differentiation of chicken embryonic stem cells into spermatogonial stem cells.
Journal of cellular biochemistry
Zhang C,Wang M,He N,Ahmed MF,Wang Y,Zhao R,Yu X,Jin J,Song J,Zuo Q,Zhang Y,Li B
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunocytochemistry
Mon Jan 01 00:00:00 EST 2018
Electroacupuncture at ST36 Increases Bone Marrow-Derived Interstitial Cells of Cajal via the SDF-1/CXCR4 and mSCF/Kit-ETV1 Pathways in the Stomach of Diabetic Mice.
Evidence-based complementary and alternative medicine : eCAM
Zhao J,An J,Liu S
Wed Mar 16 00:00:00 EDT 2022
Bioengineering functional smooth muscle with spontaneous rhythmic contraction in vitro.
Scientific reports
Kobayashi M,Khalil HA,Lei NY,Wang Q,Wang K,Wu BM,Dunn JCY
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunocytochemistry
Mon Sep 10 00:00:00 EDT 2018
Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.
Science advances
Zeng H,Yu M,Tan H,Li Y,Su W,Shi H,Dhungana Y,Guy C,Neale G,Cloer C,Peng J,Wang D,Chi H
14-1172 was used in Flow cytometry/Cell sorting to determine the mechanism by which interleukin-7 in early B lymphopoeisis and the role of Stat5-dependent and independent pathways in this process.
Mon Jan 01 00:00:00 EST 2018
Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract.
Aging
Sun T,Li D,Hu S,Huang L,Sun H,Yang S,Wu B,Ji F,Zhou D
14-1172 was used in Immunohistochemistry-immunofluorescence to study ageing-associated differences between different organs and the exact time to start degenerating.
Tue Dec 11 00:00:00 EST 2018
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.
Proceedings of the National Academy of Sciences of the United States of America
Chang CH,Kuo CJ,Ito T,Su YY,Jiang ST,Chiu MH,Lin YH,Nist A,Mernberger M,Stiewe T,Ito S,Wakamatsu K,Hsueh YA,Shieh SY,Snir-Alkalay I,Ben-Neriah Y
14-1172-82 was used in Functional assay to characterize the role of CK1α (encoded by Csnk1a1) in skin physiology.
Tue Sep 19 00:00:00 EDT 2017
Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine.
American journal of physiology. Gastrointestinal and liver physiology
Malysz J,Gibbons SJ,Saravanaperumal SA,Du P,Eisenman ST,Cao C,Oh U,Saur D,Klein S,Ordog T,Farrugia G
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunofluorescence
Wed Mar 01 00:00:00 EST 2017
Low Testosterone Alters the Activity of Mouse Prostate Stem Cells.
The Prostate
Zhou Y,Copeland B,Otto-Duessel M,He M,Markel S,Synold TW,Jones JO
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Tumor necrosis factor alpha derived from classically activated "M1" macrophages reduces interstitial cell of Cajal numbers.
Neurogastroenterology and motility
Eisenman ST,Gibbons SJ,Verhulst PJ,Cipriani G,Saur D,Farrugia G
14-1172 was used in Immunocytochemistry to determine if secreted factors from M1 macrophages could injure mouse interstitial cells of Cajal in primary culture.
Sat Apr 01 00:00:00 EDT 2017
Electroacupuncture at ST36 Protects ICC Networks via mSCF/Kit-ETV1 Signaling in the Stomach of Diabetic Mice.
Evidence-based complementary and alternative medicine : eCAM
Tian L,Zhu B,Liu S
14-1172 was used in Immunofluorescence to assess the variations of interstitial cells of Cajal (ICC) and explore the changes in mSCF/KIT-ETV1 signaling in the antrum and corpus of diabetic mice after treatment with EA.
Wed Mar 16 00:00:00 EDT 2022
A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing.
Stem cell reports
Astuti Y,Kramer AC,Blake AL,Blazar BR,Tolar J,Taisto ME,Lund TC
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Tue Jan 10 00:00:00 EST 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Mon Jan 09 00:00:00 EST 2017
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.
Cell
Puram RV,Kowalczyk MS,de Boer CG,Schneider RK,Miller PG,McConkey M,Tothova Z,Tejero H,Heckl D,Järås M,Chen MC,Li H,Tamayo A,Cowley GS,Rozenblatt-Rosen O,Al-Shahrour F,Regev A,Ebert BL
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Thu Apr 07 00:00:00 EDT 2016
Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.
The Journal of experimental medicine
Henry EK,Sy CB,Inclan-Rico JM,Espinosa V,Ghanny SS,Dwyer DF,Soteropoulos P,Rivera A,Siracusa MC
14117282 was used in flow cytometry to find a role for Car enzymes in regulating mast cell lineage commitment
Mon Aug 22 00:00:00 EDT 2016
Diabetic mice lacking macrophages are protected against the development of delayed gastric emptying.
Cellular and molecular gastroenterology and hepatology
Cipriani G,Gibbons SJ,Verhulst PJ,Choi KM,Eisenman ST,Hein SS,Ordog T,Linden DR,Szurszewski JH,Farrugia G
14-1172 was used in Immunohistochemistry to determine the role of macrophages in the development of delayed gastric emptying, in diabetic gastroparesis, using Csf1(op/op) mice.
Fri Jan 01 00:00:00 EST 2016
Stimulus-induced pacemaker activity in interstitial cells of Cajal associated with the deep muscular plexus of the small intestine.
Neurogastroenterology and motility
Zhu YF,Wang XY,Parsons SP,Huizinga JD
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunocytochemistry
Fri Jul 01 00:00:00 EDT 2016
Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs.
Nature communications
Lai M,Gonzalez-Martin A,Cooper AB,Oda H,Jin HY,Shepherd J,He L,Zhu J,Nemazee D,Xiao C
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal.
Cell death & disease
Le Q,Yao W,Chen Y,Yan B,Liu C,Yuan M,Zhou Y,Ma L
14117282 was used in flow cytometry to use knockout mice to determine if GRK6 contributes to hematopoiesis
Thu Nov 24 00:00:00 EST 2016
Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma.
Oncotarget
Adachi E,Sakai K,Nishiuchi T,Imamura R,Sato H,Matsumoto K
14-1172 was used in Flow cytometry/Cell sorting to show that malignant melanoma has the ability to undergo phenotypic change by a cell-intrinsic/autonomous mechanism that can be characterised by Met expression.
Tue Oct 25 00:00:00 EDT 2016
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
Nature
Wong TN,Ramsingh G,Young AL,Miller CA,Touma W,Welch JS,Lamprecht TL,Shen D,Hundal J,Fulton RS,Heath S,Baty JD,Klco JM,Ding L,Mardis ER,Westervelt P,DiPersio JF,Walter MJ,Graubert TA,Ley TJ,Druley T,Link DC,Wilson RK
14-1172 was used in Flow cytometry/Cell sorting to investigate how prior exposure to cytotoxic therapy influences leukemogenesis and TP53 mutations in t-AML/t-MDS patients.
Thu Feb 26 00:00:00 EST 2015
Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity.
PLoS pathogens
Napier RJ,Norris BA,Swimm A,Giver CR,Harris WA,Laval J,Napier BA,Patel G,Crump R,Peng Z,Bornmann W,Pulendran B,Buller RM,Weiss DS,Tirouvanziam R,Waller EK,Kalman D
14-1172 was used in Neutralization experiments to demonstrate that potentiation of the immune response by imatinib may facilitate clearance of diverse microbial pathogens.
Sun Mar 01 00:00:00 EST 2015
The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression.
The Journal of experimental medicine
Male V,Nisoli I,Kostrzewski T,Allan DS,Carlyle JR,Lord GM,Wack A,Brady HJ
14-1172 was used in Flow cytometry/Cell sorting to propose that E4bp4 is required for commitment to the NK lineage and can promote NK development by directly regulating the expression of the downstream transcription factors Eomes and Id2.
Mon Apr 07 00:00:00 EDT 2014
High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias.
The Journal of experimental medicine
Shin JY,Hu W,Naramura M,Park CY
14-1172 was used in Functional assays to demonstrate that HSCs exhibiting enhanced self-renewal potential can be isolated based on c-Kit expression during both steady state and stress haematopoiesis.
Mon Feb 10 00:00:00 EST 2014
Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kim TS,Cavnar MJ,Cohen NA,Sorenson EC,Greer JB,Seifert AM,Crawley MH,Green BL,Popow R,Pillarsetty N,Veach DR,Ku AT,Rossi F,Besmer P,Antonescu CR,Zeng S,Dematteo RP
14-1172 was used in Flow cytometry/Cell sorting to explore the ability of PLX3397 to deplete tumour-associated macrophages in gastrointestinal stromal cancer models.
Thu May 01 00:00:00 EDT 2014
Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Seifi M,Brown JF,Mills J,Bhandari P,Belelli D,Lambert JJ,Rudolph U,Swinny JD
14-1172 was used in Immunohistochemistry to investigate the molecular and functional diversity of GABA-A receptors in the mouse colon.
Wed Jul 30 00:00:00 EDT 2014
The origin of segmentation motor activity in the intestine.
Nature communications
Huizinga JD,Chen JH,Zhu YF,Pawelka A,McGinn RJ,Bardakjian BL,Parsons SP,Kunze WA,Wu RY,Bercik P,Khoshdel A,Chen S,Yin S,Zhang Q,Yu Y,Gao Q,Li K,Hu X,Zarate N,Collins P,Pistilli M,Ma J,Zhang R,Chen D
14-1172 was used in Immunohistochemistry to show that segmentation motor patterns in the small intestine can occur after total nerve blockade, and propose an alternate mechanism for their origin.
Mon Nov 02 00:00:00 EST 2015
Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E.
Immunity
Cheng LE,Hartmann K,Roers A,Krummel MF,Locksley RM
14-1172 was used in Flow cytometry/Cell sorting to investigate the mechanism by which perivascular mast cells acquire IgE from the blood.
Thu Jan 24 00:00:00 EST 2013
COP1 targets C/EBPα for degradation and induces acute myeloid leukemia via Trib1.
Blood
Yoshida A,Kato JY,Nakamae I,Yoneda-Kato N
14-1172 was used in Flow cytometry/Cell sorting to investigate the role of COP1 in tumourigenesis.
Thu Sep 05 00:00:00 EDT 2013
MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.
The Journal of experimental medicine
Baba T,Naka K,Morishita S,Komatsu N,Hirao A,Mukaida N
14-1172 was used in Flow cytometry/Cell sorting to investigate the interaction between leukaemia-initiating cells and normal hematopoietic cells at the early phase of chronic myeloid leukaemia, showing MIP-1α/CCL3-mediated maintenance of initiating cells.
Mon Nov 18 00:00:00 EST 2013
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
The Journal of experimental medicine
Gautier EL,Westerterp M,Bhagwat N,Cremers S,Shih A,Abdel-Wahab O,Lütjohann D,Randolph GJ,Levine RL,Tall AR,Yvan-Charvet L
14-1172 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms leading to high metabolic rate in myeloproliferative disorders, showing that HDL and Glut1 inhibition reverse hypermetabolic state.
Mon Feb 11 00:00:00 EST 2013
TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis.
Journal of immunology (Baltimore, Md. : 1950)
Oh MH,Oh SY,Lu J,Lou H,Myers AC,Zhu Z,Zheng T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2013
TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis.
Journal of immunology (Baltimore, Md. : 1950)
Oh MH,Oh SY,Lu J,Lou H,Myers AC,Zhu Z,Zheng T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2013
Are interstitial cells of Cajal involved in mechanical stress-induced gene expression and impairment of smooth muscle contractility in bowel obstruction?
PloS one
Wu CC,Lin YM,Gao J,Winston JH,Cheng LK,Shi XZ
14-1172 was used in Immunofluorescence to test the hypothesis that mechanical dilation in obstruction disrupts the ICC network and that ICC do not mediate mechanotranscription of COX-2.
Mon Jun 16 00:00:00 EDT 2014
FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation.
Development (Cambridge, England)
Ishii K,Kanatsu-Shinohara M,Toyokuni S,Shinohara T
14-1172 was used in Flow cytometry/Cell sorting to assess the role of the FGF2 signalling pathway for SSC self-renewal.
Tue May 01 00:00:00 EDT 2012
Mast cell deficiency attenuates progression of atherosclerosis and hepatic steatosis in apolipoprotein E-null mice.
American journal of physiology. Heart and circulatory physiology
Smith DD,Tan X,Raveendran VV,Tawfik O,Stechschulte DJ,Dileepan KN
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunohistochemistry
Fri Jun 15 00:00:00 EDT 2012
Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117.
PloS one
Saran N,Pommerencke J,Witzlau K,Regelin M,Krueger A
14-1172 was used in Flow cytometry/Cell sorting to suggest that a physiological thymic microenvironment does not optimally support T cell differentiation from triple negative precursors.
Mon Jun 18 00:00:00 EDT 2012
Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950)
Busche A,Schmitz S,Fleige H,Robbins SH,Walzer T,Stewart CA,Förster R,Messerle M,Prinz I
14-1172 was used in Flow cytometry/Cell sorting to determine that antiviral immune responses may induce sustained alterations in natural killer cell populations.
Tue Mar 01 00:00:00 EST 2011
On the origin of rhythmic calcium transients in the ICC-MP of the mouse small intestine.
American journal of physiology. Gastrointestinal and liver physiology
Lowie BJ,Wang XY,White EJ,Huizinga JD
14-1172 was used in Immunocytochemistry to elucidate the origins of the calcium transients.
Tue Nov 01 00:00:00 EDT 2011
Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats.
Biology of reproduction
Mark-Kappeler CJ,Sen N,Lukefahr A,McKee L,Sipes IG,Konhilas J,Hoyer PB
14-1172 was used in Blocking experiments to demonstrate that 4-vinylcyclohexene diepoxide induces ovotoxicity by direct inhibition of KIT autophosphorylation of the oocyte.
Sat Oct 01 00:00:00 EDT 2011
Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse.
Development (Cambridge, England)
Sasaki T,Mizuochi C,Horio Y,Nakao K,Akashi K,Sugiyama D
14-1172 was used in Immunohistochemistry to demonstrate that placental hematopoietic cell clusters originate from the allantois and are regulated by endothelial niche cells via SCF/Kit signalling.
Wed Dec 01 00:00:00 EST 2010
ETV5 regulates sertoli cell chemokines involved in mouse stem/progenitor spermatogonia maintenance.
Stem cells (Dayton, Ohio)
Simon L,Ekman GC,Garcia T,Carnes K,Zhang Z,Murphy T,Murphy KM,Hess RA,Cooke PS,Hofmann MC
14-1172 was used in Flow cytometry/Cell sorting to show for the first time that Sertoli cells are chemoattractive for stem/progenitor spermatogonia, and that production of specific chemokines is regulated by ETV5.
Fri Oct 01 00:00:00 EDT 2010
Time-dependent disruption of oviduct pacemaker cells by Chlamydia infection in mice.
Biology of reproduction
Dixon RE,Ramsey KH,Schripsema JH,Sanders KM,Ward SM
14-1172 was used in Immunohistochemistry to examine the inflammatory mediator responsible for damage to oviduct interstitial cells of Cajal networks and pacemaker activity, during Chlamydia trachomatis infection.
Sun Aug 01 00:00:00 EDT 2010
Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo.
Neurogastroenterology and motility
Tharayil VS,Wouters MM,Stanich JE,Roeder JL,Lei S,Beyder A,Gomez-Pinilla PJ,Gershon MD,Maroteaux L,Gibbons SJ,Farrugia G
14-1172 was used in Immunohistochemistry to suggest that 5-HT2B receptor signaling is required for maintenance of interstitial cells of Cajal networks.
Thu Apr 01 00:00:00 EDT 2010
Increased aortic atherosclerotic plaque development in female apolipoprotein E-null mice is associated with elevated thromboxane A2 and decreased prostacyclin production.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Smith DD,Tan X,Tawfik O,Milne G,Stechschulte DJ,Dileepan KN
14-1172 was used in Immunohistochemistry to identify TXA(2) and PGI(2) production as gender-related proatherogenic risk factors.
Tue Jun 01 00:00:00 EDT 2010
Bone marrow derivation of interstitial cells of cajal in small intestine following intestinal injury.
Journal of biomedicine & biotechnology
Liu D,Wang F,Zou Z,Dong S,Wang J,Ran X,Li C,Shi C,Su Y
14-1172 was used in Immunocytochemistry to study whether bone marrow-derived cells can differentiate into Interstitial cells of Cajal and contribute to their regeneration using GFP-transgenic mice.
Tue Jul 13 00:00:00 EDT 2010
The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage.
Nature
Lancrin C,Sroczynska P,Stephenson C,Allen T,Kouskoff V,Lacaud G
14-1172 was used in Immunohistochemistry to merge the two a priori conflicting theories on the origin of haematopoietic development into a single linear developmental process.
Thu Feb 12 00:00:00 EST 2009
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Cancer cell
Erler JT,Bennewith KL,Cox TR,Lang G,Bird D,Koong A,Le QT,Giaccia AJ
14-1172 was used in Immunofluorescence to demonstrate a critical role for LOX in premetastatic niche formation.
Tue Jan 06 00:00:00 EST 2009
MLL5 contributes to hematopoietic stem cell fitness and homeostasis.
Blood
Zhang Y,Wong J,Klinger M,Tran MT,Shannon KM,Killeen N
14-1172 was used in Flow cytometry/Cell sorting to show that inactivation of the Mll5 gene in mice results in the reduction in frequency and function of haematopoietic stem cells.
Thu Feb 12 00:00:00 EST 2009
Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues.
The American journal of pathology
Vitsky A,Waire J,Pawliuk R,Bond A,Matthews D,Lacasse E,Hawes ML,Nelson C,Richards S,Piepenhagen PA,Garman RD,Andrews L,Thurberg BL,Lonning S,Ledbetter S,Ruzek MC
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 14-1172-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2009
Identification of TRPM7 channels in human intestinal interstitial cells of Cajal.
World journal of gastroenterology
Kim BJ,Park KJ,Kim HW,Choi S,Jun JY,Chang IY,Jeon JH,So I,Kim SJ
14-1172 was used in Immunohistochemistry-immunofluorescence to investigate the characteristics of slow electrical waves and the presence of transient receptor potential melastatin-type 7 in the human gastrointestinal tract.
Mon Dec 14 00:00:00 EST 2009
Ca2+-activated K+ current in freshly isolated c-Kit positive cells in guinea-pig stomach.
Journal of Korean medical science
Kim YC,Suzuki H,Xu WX,Choi W,Kim SH,Lee SJ
14-1172 was used in Immunohistochemistry to identify and elucidate the physiological relevance of Ca2+-activated K+ currents in freshly isolated guinea pig interstitial cells of Cajal.
Mon Jun 01 00:00:00 EDT 2009
Stem cell factor functions as an outgrowth-promoting factor to enable axon exit from the midline intermediate target.
Neuron
Gore BB,Wong KG,Tessier-Lavigne M
14-1172 was used in Immunohistochemistry to examine the role and mechanisms of stem cell factor as a guidance cue in the central nervous system.
Thu Feb 28 00:00:00 EST 2008
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy.
The American journal of pathology
Wallace GQ,Lapidos KA,Kenik JS,McNally EM
14-1172 was used in Flow cytometry/Cell sorting to examine the capacity of single injections of adult muscle mononuclear cells to provide long-term benefit for muscular dystrophy in delta-sarcoglycan-null dystrophic immunocompetent mice.
Mon Sep 01 00:00:00 EDT 2008
Voltage-dependent Ca Current Identified in Freshly Isolated Interstitial Cells of Cajal (ICC) of Guinea-pig Stomach.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Kim YC,Suzuki H,Xu WX,Hashitani H,Choi W,Yun HY,Park SM,Youn SJ,Lee SJ,Lee SJ
14-1172 was used in Immunohistochemistry to demonstrate that ICC-MY potently produce dihydropiridine sensitive L-type voltage-dependent Ca(2+) currents.
Mon Dec 01 00:00:00 EST 2008
Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors.
Gastroenterology
Wouters MM,Gibbons SJ,Roeder JL,Distad M,Ou Y,Strege PR,Szurszewski JH,Farrugia G
14-1172-82 was used in Immunocytochemistry to examine whether 5-hydroxytryptamine plays a role in regulating the proliferation of interstitial cells of Cajal.
Sat Sep 01 00:00:00 EDT 2007
Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche.
Cell stem cell
Yoshihara H,Arai F,Hosokawa K,Hagiwara T,Takubo K,Nakamura Y,Gomei Y,Iwasaki H,Matsuoka S,Miyamoto K,Miyazaki H,Takahashi T,Suda T
14-1172 was used in Immunohistochemistry to investigate the role of signalling via THPO and its receptor, MPL, in the interaction of quiescent HSCs with their niche.
Thu Dec 13 00:00:00 EST 2007
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment.
Immunity
Nagai Y,Garrett KP,Ohta S,Bahrun U,Kouro T,Akira S,Takatsu K,Kincade PW
14-1172 was used in Flow cytometry/Cell sorting to investigate the expression of toll-like receptors on different hematopoietic stem cells and the mechanism by which they stimulate innate immune system replenishment.
Thu Jun 01 00:00:00 EDT 2006
Melastatin-type transient receptor potential channel 7 is required for intestinal pacemaking activity.
Gastroenterology
Kim BJ,Lim HH,Yang DK,Jun JY,Chang IY,Park CS,So I,Stanfield PR,Kim KW
14-1172 was used in Immunohistochemistry to demonstrate that melastatin-type transient receptor potential channel 7 is necessary for intestinal pacemaking.
Tue Nov 01 00:00:00 EST 2005
Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility.
Journal of cell science
Nakayama S,Ohya S,Liu HN,Watanabe T,Furuzono S,Wang J,Nishizawa Y,Aoyama M,Murase N,Matsubara T,Ito Y,Imaizumi Y,Kajioka S
14-1172 was used in Immunofluorescence to suggest that sulphonylurea receptors (SUR) can modulate pacemaker [Ca2+]i oscillations via voltage-independent mechanism(s).
Thu Sep 15 00:00:00 EDT 2005
