Invitrogen

ATG7 Polyclonal Antibody

View all (29) ATG7 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-35204

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100
-

Immunocytochemistry (ICC/IF)

1:25
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 540-569 amino acids from the C-terminal region of human ATG7
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2552514

Product Specific Information

This antibody is predicted to react with chicken, mouse and rat based on sequence homology.

Target Information

This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: APG7-like; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; DKFZp434N0735; hAGP7; Ubiquitin-activating enzyme E1-like protein; Ubiquitin-like modifier-activating enzyme ATG7

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Gene Aliases: 1810013K23Rik; Agp7; APG7-LIKE; APG7L; ATG7; Atg7l; Gm21553; GSA7

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UniProt ID: (Human) O95352, (Mouse) Q9D906

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Entrez Gene ID: (Human) 10533, (Mouse) 74244

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Function(s)
ubiquitin activating enzyme activity protein binding transcription factor binding Atg12 activating enzyme activity Atg8 activating enzyme activity protein homodimerization activity small protein activating enzyme activity ubiquitin-protein ligase
Process(es)
cellular protein modification process protein lipidation C-terminal protein lipidation cellular response to nitrogen starvation cellular response to starvation positive regulation of autophagy protein transport macroautophagy positive regulation of macroautophagy protein ubiquitination positive regulation of protein modification process piecemeal microautophagy of nucleus suppression by virus of host autophagy positive regulation of apoptotic process late nucleophagy positive regulation of protein catabolic process defense response to virus membrane fusion cellular response to hyperoxia regulation of mitophagy autophagosome assembly mitophagy liver development cellular amino acid metabolic process transport autophagy organelle organization mitochondrion organization adult walking behavior post-embryonic development cerebellar Purkinje cell layer development pyramidal neuron development central nervous system neuron axonogenesis cerebral cortex development protein catabolic process neuron projection development regulation of protein ubiquitination protein modification by small protein conjugation negative stranded viral RNA replication response to starvation negative regulation of apoptotic process neurological system process cardiac muscle cell development regulation of cell development negative regulation of cell death membrane organization positive regulation of mucus secretion regulation of hemopoiesis negative regulation of histone H4-K16 acetylation
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