Product References
Selective Inhibition of Soluble Tumor Necrosis Factor Alters the Neuroinflammatory Response following Moderate Spinal Cord Injury in Mice.
Biology
Lund MC,Ellman DG,Nielsen PV,Raffaele S,Fumagalli M,Guzman R,Degn M,Brambilla R,Meyer M,Clausen BH,Lambertsen KL
A-21294 was used in Immunohistochemistry to suggest that selective targeting of solTNF time-dependently modulates the neuroinflammatory response by favoring a pro-regenerative environment in the lesioned spinal cord, leading to improved functional outcomes.
Mon Jun 12 00:00:00 EDT 2023
The Inflammatory Response after Moderate Contusion Spinal Cord Injury: A Time Study.
Biology
Lund MC,Ellman DG,Nissen M,Nielsen PS,Nielsen PV,Jørgensen C,Andersen DC,Gao H,Brambilla R,Degn M,Clausen BH,Lambertsen KL
A-21294 was used in Immunocytochemistry, Immunohistochemistry to support the consensus that future neuroprotective immunotherapies should aim to selectively neutralize detrimental immune signaling while sustaining pro-regenerative processes.
Mon Jun 20 00:00:00 EDT 2022
Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis.
Frontiers in neuroscience
O'Sullivan SJ,Malahias E,Park J,Srivastava A,Reyes BAS,Gorky J,Vadigepalli R,Van Bockstaele EJ,Schwaber JS
Published figure using GFAP monoclonal antibody (Product # A-21294) in Immunocytochemistry
Thu Oct 01 00:00:00 EDT 2020
Aberrant expression of the pore-forming KATP channel subunit Kir6.2 in hippocampal reactive astrocytes in the 3xTg-AD mouse model and human Alzheimer's disease.
Neuroscience
Griffith CM,Xie MX,Qiu WY,Sharp AA,Ma C,Pan A,Yan XX,Patrylo PR
A21294 was used in immunohistochemistry to ask if Kir6.1 and Kir6.2 are altered in the hippocampus in a cell type-specific manner in Alzheimer's disease
Sat Nov 12 00:00:00 EST 2016
Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways.
Journal of virology
Steffensen MA,Fenger C,Christensen JE,Jørgensen CK,Bassi MR,Christensen JP,Finsen B,Thomsen AR
A-21294 was used in immunohistochemistry (frozen) to study mechanisms regulating SOCS expression during viral infection.
Mon Dec 01 00:00:00 EST 2014
Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways.
Journal of virology
Steffensen MA,Fenger C,Christensen JE,Jørgensen CK,Bassi MR,Christensen JP,Finsen B,Thomsen AR
A-21294 was used in immunohistochemistry (frozen) to study mechanisms regulating SOCS expression during viral infection.
Mon Dec 01 00:00:00 EST 2014
Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species.
Neurobiology of aging
Ghosh D,LeVault KR,Brewer GJ
A-21294 was used in immunocytochemistry to investigate the role of reactive oxygen species in neuron loss, aging, and Alzheimer's disease.
Wed Jan 01 00:00:00 EST 2014
Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3.
Frontiers in neural circuits
Brewer GJ,Boehler MD,Leondopulos S,Pan L,Alagapan S,DeMarse TB,Wheeler BC
Published figure using GFAP monoclonal antibody (Product # A-21294) in Immunofluorescence
Tue Apr 08 00:00:00 EDT 2014
IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival.
Clinical cancer research : an official journal of the American Association for Cancer Research
Wainwright DA,Balyasnikova IV,Chang AL,Ahmed AU,Moon KS,Auffinger B,Tobias AL,Han Y,Lesniak MS
A-21294 was used in immunohistochemistry (frozen) to study the role of indoleamine 2,3 dioxygenase in brain tumors and the impact on Treg recruitment.
Thu Nov 15 00:00:00 EST 2012
Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery.
Journal of virology
Christensen JE,Fenger C,Issazadeh-Navikas S,Krug A,Liljestrøm P,Goriely S,Paludan SR,Finsen B,Christensen JP,Thomsen AR
A-21294 was used in immunohistochemistry (frozen) to elucidate mechanisms involved in virus-induced central nervous system inflammation.
Sun Jul 01 00:00:00 EDT 2012
Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery.
Journal of virology
Christensen JE,Fenger C,Issazadeh-Navikas S,Krug A,Liljestrøm P,Goriely S,Paludan SR,Finsen B,Christensen JP,Thomsen AR
A-21294 was used in immunohistochemistry (frozen) to elucidate mechanisms involved in virus-induced central nervous system inflammation.
Sun Jul 01 00:00:00 EDT 2012
A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells.
Journal of neuroinflammation
Furr SR,Chauhan VS,Moerdyk-Schauwecker MJ,Marriott I
A-21294 was used in flow cytometry to investigate the expression and role of DAI in the inflammatory responses of resident CNS cells to neurotropic DNA viruses.
Fri Aug 12 00:00:00 EDT 2011
Vesicular stomatitis virus infects resident cells of the central nervous system and induces replication-dependent inflammatory responses.
Virology
Chauhan VS,Furr SR,Sterka DG,Nelson DA,Moerdyk-Schauwecker M,Marriott I,Grdzelishvili VZ
A-21294 was used in flow cytometry to investigate the effect of vesicular stomatitis virus infection on CNS system and inflammation induction
Mon May 10 00:00:00 EDT 2010
Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy.
Neuroscience letters
Wainwright DA,Xin J,Mesnard NA,Sanders VM,Jones KJ
A-21294 was used in immunohistochemistry - frozen section to explore role of TLR2 in the facial motoneuron response to axotomy
Fri Feb 26 00:00:00 EST 2010
A new method to isolate microglia from adult mice and culture them for an extended period of time.
Journal of neuroscience methods
Moussaud S,Draheim HJ
A-21294 was used in flow cytometry to isolate and characterize microglia from adult mouse brains
Tue Mar 30 00:00:00 EDT 2010
The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma.
PloS one
Wainwright DA,Sengupta S,Han Y,Ulasov IV,Lesniak MS
A-21294 was used in immunohistochemistry - frozen section to study Th17 cells in glia-derived tumors of the central nervous system
Sat Oct 23 00:00:00 EDT 2010
Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade.
Journal of immunology (Baltimore, Md. : 1950)
Christensen JE,Simonsen S,Fenger C,Sørensen MR,Moos T,Christensen JP,Finsen B,Thomsen AR
A-21294 was used in immunohistochemistry - frozen section to address the mechanisms regulating the expression of CXCL10 in the central nervous system of lymphocytic choriomeningitis virus -infected mice
Thu Jan 15 00:00:00 EST 2009
Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice.
Journal of neuroimmunology
Wainwright DA,Xin J,Mesnard NA,Politis CM,Sanders VM,Jones KJ
A-21294 was used in immunohistochemistry - frozen section to investigate the role of CXCL11 in facial motoneuron survival
Mon Nov 30 00:00:00 EST 2009
Monitoring the protective effects of minocycline treatment with radiolabeled annexin V in an experimental model of focal cerebral ischemia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Tang XN,Wang Q,Koike MA,Cheng D,Goris ML,Blankenberg FG,Yenari MA
A-21294 was used in immunohistochemistry - frozen section to assess the use of (99m)Tc-annexin V with SPECT to monitor the antiapoptotic effects of minocycline therapy
Thu Nov 01 00:00:00 EDT 2007
