Product References
Mast cells link immune sensing to antigen-avoidance behaviour.
Nature
Plum T,Binzberger R,Thiele R,Shang F,Postrach D,Fung C,Fortea M,Stakenborg N,Wang Z,Tappe-Theodor A,Poth T,MacLaren DAA,Boeckxstaens G,Kuner R,Pitzer C,Monyer H,Xin C,Bonventre JV,Tanaka S,Voehringer D,Vanden Berghe P,Strid J,Feyerabend TB,Rodewald HR
56-5321-82 was used in Flow cytometry/Cell sorting to identify the immunological sensor cell linking antigen recognition to avoidance behaviour.
Tue Aug 01 00:00:00 EDT 2023
Embryonic keratin19+ progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla.
Nature communications
Lucas B,White AJ,Klein F,Veiga-Villauriz C,Handel A,Bacon A,Cosway EJ,James KD,Parnell SM,Ohigashi I,Takahama Y,Jenkinson WE,Hollander GA,Lu WY,Anderson G
56-5321-82 was used in Flow cytometry/Cell sorting to identify and define a multipotent mTEC progenitor that emerges during embryogenesis to support mTEC diversity into adult life.
Wed Apr 12 00:00:00 EDT 2023
Prolonged dysbiosis and altered immunity under nutritional intervention in a physiological mouse model of severe acute malnutrition.
iScience
Hidalgo-Villeda F,Million M,Defoort C,Vannier T,Svilar L,Lagier M,Wagner C,Arroyo-Portilla C,Chasson L,Luciani C,Bossi V,Gorvel JP,Lelouard H,Tomas J
56-5321-82 was used in Flow cytometry/Cell sorting to provide a preclinical model of SAM and have identified key markers to target with future interventions during the education of the immune system to improve SAM whole defects.
Fri Jun 16 00:00:00 EDT 2023
CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity.
Nature immunology
Gressier E,Schulte-Schrepping J,Petrov L,Brumhard S,Stubbemann P,Hiller A,Obermayer B,Spitzer J,Kostevc T,Whitney PG,Bachem A,Odainic A,van de Sandt C,Nguyen THO,Ashhurst T,Wilson K,Oates CVL,Gearing LJ,Meischel T,Hochheiser K,Greyer M,Clarke M,Kreutzenbeck M,Gabriel SS,Kastenmüller W,Kurts C,Londrigan SL,Kallies A,Kedzierska K,Hertzog PJ,Latz E,Chen YE,Radford KJ,Chopin M,Schroeder J,Kurth F,Gebhardt T,Sander LE,Sawitzki B,Schultze JL,Schmidt SV,Bedoui S
56-5321-82 was used in Flow cytometry/Cell sorting to describe gradual interferon-α/interferon-β (IFNα/β)-induced transcriptional adaptations that endow APCs with the capacity to rapidly activate the transcriptional regulators p65, IRF1 and FOS after CD4+ T cell-mediated CD40 stimulation.
Thu Jun 01 00:00:00 EDT 2023
Plasmodium infection disrupts the T follicular helper cell response to heterologous immunization.
eLife
Fontana MF,Ollmann Saphire E,Pepper M
56-5321-82 was used in Flow cytometry/Cell sorting to provide mechanistic insight into the development of both Plasmodium-specific and heterologous adaptive responses in hosts with malaria.
Mon Jan 30 00:00:00 EST 2023
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2.
Cell
Afkhami S,D'Agostino MR,Zhang A,Stacey HD,Marzok A,Kang A,Singh R,Bavananthasivam J,Ye G,Luo X,Wang F,Ang JC,Zganiacz A,Sankar U,Kazhdan N,Koenig JFE,Phelps A,Gameiro SF,Tang S,Jordana M,Wan Y,Mossman KL,Jeyanathan M,Gillgrass A,Medina MFC,Smaill F,Lichty BD,Miller MS,Xing Z
56-5321-82 was used in Flow Cytometry to indicate that respiratory mucosal delivery of Ad-vectored multivalent vaccine represents an effective next-generation COVID-19 vaccine strategy to induce all-around mucosal immunity against current and future VOC.
Thu Mar 03 00:00:00 EST 2022
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Immunity
Simpson DS,Pang J,Weir A,Kong IY,Fritsch M,Rashidi M,Cooney JP,Davidson KC,Speir M,Djajawi TM,Hughes S,Mackiewicz L,Dayton M,Anderton H,Doerflinger M,Deng Y,Huang AS,Conos SA,Tye H,Chow SH,Rahman A,Norton RS,Naderer T,Nicholson SE,Burgio G,Man SM,Groom JR,Herold MJ,Hawkins ED,Lawlor KE,Strasser A,Silke J,Pellegrini M,Kashkar H,Feltham R,Vince JE
56-5321-82 was used in Flow Cytometry to reveal that iNOS selectively licenses programmed cell death, which may explain how nitric oxide impacts disease severity in SARS-CoV-2 infection and other iNOS-associated inflammatory conditions.
Tue Mar 08 00:00:00 EST 2022
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine.
Nature immunology
Li C,Lee A,Grigoryan L,Arunachalam PS,Scott MKD,Trisal M,Wimmers F,Sanyal M,Weidenbacher PA,Feng Y,Adamska JZ,Valore E,Wang Y,Verma R,Reis N,Dunham D,O'Hara R,Park H,Luo W,Gitlin AD,Kim P,Khatri P,Nadeau KC,Pulendran B
56-5321-82 was used in Flow Cytometry to provide insights into the molecular mechanisms by which the BNT162b2 vaccine stimulates immune responses.
Fri Apr 01 00:00:00 EDT 2022
A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice.
Nature communications
Lee A,Scott MKD,Wimmers F,Arunachalam PS,Luo W,Fox CB,Tomai M,Khatri P,Pulendran B
56-5321-82 was used in Flow Cytometry to profile the kinetics, transcriptomics and epigenomics of innate immune cells in murine draining lymph nodes following 3M-052-Alum/Ovalbumin immunization.
Thu Jan 27 00:00:00 EST 2022
RXRα Regulates the Development of Resident Tissue Macrophages.
ImmunoHorizons
Philpott J,Kazimierczyk S,Korgaonkar P,Bordt E,Zois J,Vasudevan C,Meng D,Bhatia I,Lu N,Jimena B,Porter C,Cherayil BJ,Jain N
56-5321-82 was used in Flow cytometry/Cell sorting to show that the ligand-activated nuclear hormone receptor, retinoid X receptor (RXR)α, is a key regulator of murine RTM development.
Wed Jun 22 00:00:00 EDT 2022
CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia.
Nature communications
Allouch A,Voisin L,Zhang Y,Raza SQ,Lecluse Y,Calvo J,Selimoglu-Buet D,de Botton S,Louache F,Pflumio F,Solary E,Perfettini JL
56-5321-82 was used in Flow cytometry/Cell sorting to reveal p21 as a trigger of phagocytosis-guided pro-inflammatory TAM reprogramming and highlight the potential for p21TD-Mo-based cellular therapy as a cancer immunotherapy.
Tue Nov 08 00:00:00 EST 2022
Toll-like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-induced Gastric Metaplasias.
Gastroenterology
Ding L,Chakrabarti J,Sheriff S,Li Q,Thi Hong HN,Sontz RA,Mendoza ZE,Schreibeis A,Helmrath MA,Zavros Y,Merchant JL
56-5321-82 was used in Flow Cytometry to propose that individuals with a more robust response to damage-activated molecular patterns and increased Toll-like receptor 9 (TLR9) expression are predisposed to the neoplastic complications of Helicobacter infection.
Mon Aug 01 00:00:00 EDT 2022
A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis.
Immunology and cell biology
Zhang L,Feng X,Shen Y,Wang Y,Liu Z,Ma Y,Gu Y,Guo G,Duan L,Lu L,Liang Y,Lawrence T,Huang R
56-5321-82 was used in Flow cytometry/Cell sorting to demonstrate that the ZsGreen-expressing YUMM1.7 melanoma model provides a valuable tool for the study of phagocytosis in vivo.
Sat Oct 01 00:00:00 EDT 2022
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Jul 08 00:00:00 EDT 2021
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Jul 08 00:00:00 EDT 2021
Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies.
Cell host & microbe
Huang X,Hurabielle C,Drummond RA,Bouladoux N,Desai JV,Sim CK,Belkaid Y,Lionakis MS,Segre JA
56-5321-82 was used in Flow Cytometry to develop a murine skin topical exposure model for C. auris to dissect risk factors for colonization and to test interventions that might protect patients.
Wed Feb 10 00:00:00 EST 2021
Skin inflammation activates intestinal stromal fibroblasts and promotes colitis.
The Journal of clinical investigation
Dokoshi T,Seidman JS,Cavagnero KJ,Li F,Liggins MC,Taylor BC,Olvera J,Knight R,Chang JT,Salzman NH,Gallo RL
56-5321-82 was used in Flow Cytometry to understand whether fibroblasts participate in the pathogenesis of inflammatory bowel diseases and if hyaluronan could act as a signal from the skin to alter intestinal immune function through effects on fat cell differentiation.
Mon Nov 01 00:00:00 EDT 2021
Regionally diverse astrocyte subtypes and their heterogeneous response to EAE.
Glia
Borggrewe M,Grit C,Vainchtein ID,Brouwer N,Wesseling EM,Laman JD,Eggen BJL,Kooistra SM,Boddeke EWGM
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages.
Immune network
Sim H,Jeong D,Kim HI,Pak S,Thapa B,Kwon HJ,Lee K
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2.
Cell death discovery
Zhou N,Liu W,Zhang W,Liu Y,Li X,Wang Y,Zheng R,Zhang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.
Scientific reports
Mittal A,Wang M,Vidyarthi A,Yanez D,Pizzurro G,Thakral D,Tracy E,Colegio OR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon May 24 00:00:00 EDT 2021
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.
Scientific reports
Flamant M,Mougenot N,Balse E,Le Fèvre L,Atassi F,Gautier EL,Le Goff W,Keck M,Nadaud S,Combadière C,Boissonnas A,Pavoine C
56-5321-82 was used in Flow Cytometry to characterize macrophages (Mφ) in hearts early infused with isoproterenol as compared to control and failing hearts and evaluate the role of upregulated CX3CL1 in cardiac remodeling.
Thu Sep 09 00:00:00 EDT 2021
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.
Scientific reports
Flamant M,Mougenot N,Balse E,Le Fèvre L,Atassi F,Gautier EL,Le Goff W,Keck M,Nadaud S,Combadière C,Boissonnas A,Pavoine C
56-5321-82 was used in Flow Cytometry to characterize macrophages (Mφ) in hearts early infused with isoproterenol as compared to control and failing hearts and evaluate the role of upregulated CX3CL1 in cardiac remodeling.
Thu Sep 09 00:00:00 EDT 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP.B to the brain in a mouse model of amyloidosis.
Molecular therapy. Methods & clinical development
Kofoed RH,Heinen S,Silburt J,Dubey S,Dibia CL,Maes M,Simpson EM,Hynynen K,Aubert I
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunocytochemistry
Fri Dec 10 00:00:00 EST 2021
A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.
Med (New York, N.Y.)
Silva-Cayetano A,Foster WS,Innocentin S,Belij-Rammerstorfer S,Spencer AJ,Burton OT,Fra-Bidó S,Le Lee J,Thakur N,Conceicao C,Wright D,Barrett J,Evans-Bailey N,Noble C,Bailey D,Liston A,Gilbert SC,Lambe T,Linterman MA
56-5321-82 was used in Flow Cytometry to show that ChAdOx1 nCoV-19 induces both cellular and humoral immunity in adult and aged mice and suggest a prime-boost strategy is a rational approach to enhance immunogenicity in older persons.
Fri Mar 12 00:00:00 EST 2021
Sensitive and Quantitative Detection of MHC-I Displayed Neoepitopes Using a Semiautomated Workflow and TOMAHAQ Mass Spectrometry.
Molecular & cellular proteomics : MCP
Pollock SB,Rose CM,Darwish M,Bouziat R,Delamarre L,Blanchette C,Lill JR
56-5321-82 was used in Flow Cytometry to describe a robust and quantitative method whereby peptides derived from MHC-I complexes from a variety of cell lines, including challenging adherent lines such as MC38, can be enriched in a semi-automated fashion on reusable, dry-storage, customized antibody cartridges.
Mon Mar 21 00:00:00 EDT 2022
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
Journal for immunotherapy of cancer
Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes.
Cell reports
Sano T,Kageyama T,Fang V,Kedmi R,Martinez CS,Talbot J,Chen A,Cabrera I,Gorshko O,Kurakake R,Yang Y,Ng C,Schwab SR,Littman DR
56-5321-82 was used in Flow Cytometry to show that intestine-draining mesenteric lymph nodes (MLNs), not intestine proper, are the dominant site of SFB-induced intestinal Th17 cell differentiation.
Tue Aug 24 00:00:00 EDT 2021
Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity.
Cell
Giampazolias E,Schulz O,Lim KHJ,Rogers NC,Chakravarty P,Srinivasan N,Gordon O,Cardoso A,Buck MD,Poirier EZ,Canton J,Zelenay S,Sammicheli S,Moncaut N,Varsani-Brown S,Rosewell I,Reis e Sousa C
56-5321-82 was used in Immunocytochemistry to reveal a natural barrier to cross-presentation of cancer antigens that dampens anti-tumor CD8+ T cell responses.
Thu Jul 22 00:00:00 EDT 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Feb 28 00:00:00 EST 2022
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii.
eLife
Clark JT,Christian DA,Gullicksrud JA,Perry JA,Park J,Jacquet M,Tarrant JC,Radaelli E,Silver J,Hunter CA
56-5321-82 was used in Flow cytometry/Cell sorting to investigate the role of IL-33 in innate resistance to the parasite Toxoplasma gondii.
Fri Apr 30 00:00:00 EDT 2021
Systemic Inflammation Accelerates Changes in Microglial and Synaptic Markers in an Experimental Model of Chronic Neurodegeneration.
Frontiers in neuroscience
Chouhan JK,Püntener U,Booth SG,Teeling JL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Sat Jan 22 00:00:00 EST 2022
Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.
Cell
Zhang L,Li Z,Skrzypczynska KM,Fang Q,Zhang W,O'Brien SA,He Y,Wang L,Zhang Q,Kim A,Gao R,Orf J,Wang T,Sawant D,Kang J,Bhatt D,Lu D,Li CM,Rapaport AS,Perez K,Ye Y,Wang S,Hu X,Ren X,Ouyang W,Shen Z,Egen JG,Zhang Z,Yu X
56-5321-82 was used in Flow Cytometry to identify critical cellular interactions regulating tumor immunity and defines mechanisms underlying myeloid-targeted immunotherapies currently undergoing clinical testing.
Thu Apr 16 00:00:00 EDT 2020
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Immunity
Bosteels C,Neyt K,Vanheerswynghels M,van Helden MJ,Sichien D,Debeuf N,De Prijck S,Bosteels V,Vandamme N,Martens L,Saeys Y,Louagie E,Lesage M,Williams DL,Tang SC,Mayer JU,Ronchese F,Scott CL,Hammad H,Guilliams M,Lambrecht BN
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Jun 16 00:00:00 EDT 2020
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Immunity
Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL
56-5321 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).
Tue Sep 15 00:00:00 EDT 2020
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.
Immunity
Soni C,Perez OA,Voss WN,Pucella JN,Serpas L,Mehl J,Ching KL,Goike J,Georgiou G,Ippolito GC,Sisirak V,Reizis B
56-5321-82 was used in Flow Cytometry to establish extrafollicular B cell differentiation into short-lived AFCs as a key mechanism of anti-DNA autoreactivity and reveal a major contribution of pDCs, endosomal Toll-like receptors (TLRs), and IFN-I to this pathway.
Tue Jun 16 00:00:00 EDT 2020
SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution.
Cell metabolism
Argüello RJ,Combes AJ,Char R,Gigan JP,Baaziz AI,Bousiquot E,Camosseto V,Samad B,Tsui J,Yan P,Boissonneau S,Figarella-Branger D,Gatti E,Tabouret E,Krummel MF,Pierre P
56-5321-82 was used in Flow Cytometry to analyze myeloid cells in solid tumors from patients and identified variable metabolic profiles, in ways that are not linked to their lineage or their activation phenotype.
Tue Dec 01 00:00:00 EST 2020
Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure.
Cell host & microbe
Giamarellos-Bourboulis EJ,Netea MG,Rovina N,Akinosoglou K,Antoniadou A,Antonakos N,Damoraki G,Gkavogianni T,Adami ME,Katsaounou P,Ntaganou M,Kyriakopoulou M,Dimopoulos G,Koutsodimitropoulos I,Velissaris D,Koufargyris P,Karageorgos A,Katrini K,Lekakis V,Lupse M,Kotsaki A,Renieris G,Theodoulou D,Panou V,Koukaki E,Koulouris N,Gogos C,Koutsoukou A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2020
Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer.
The Journal of experimental medicine
Etzerodt A,Moulin M,Doktor TK,Delfini M,Mossadegh-Keller N,Bajenoff M,Sieweke MH,Moestrup SK,Auphan-Anezin N,Lawrence T
56-5321 was used in Flow cytometry/Cell sorting to describe a specific role for tissue-resident macrophages in the invasive progression of metastatic ovarian cancer.
Mon Apr 06 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
Podocytes present antigen to activate specific T cell immune responses in inflammatory renal disease.
The Journal of pathology
Li S,Liu Y,He Y,Rong W,Zhang M,Li L,Liu Z,Zen K
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells.
Glia
Aires ID,Ribeiro-Rodrigues T,Boia R,Catarino S,Girão H,Ambrósio AF,Santiago AR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunocytochemistry
Tue Dec 01 00:00:00 EST 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Induced pluripotent stem cells reprogrammed from primary dendritic cells provide an abundant source of immunostimulatory dendritic cells for use in immunotherapy.
Stem cells (Dayton, Ohio)
Horton C,Davies TJ,Lahiri P,Sachamitr P,Fairchild PJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Airway Macrophages Mediate Mucosal Vaccine-Induced Trained Innate Immunity against Mycobacterium tuberculosis in Early Stages of Infection.
Journal of immunology (Baltimore, Md. : 1950)
D'Agostino MR,Lai R,Afkhami S,Khera A,Yao Y,Vaseghi-Shanjani M,Zganiacz A,Jeyanathan M,Xing Z
56-5321-82 was used in Flow Cytometry to reveal an important role of AwM in innate immune protection in early stages of M. tuberculosis infection in the lung.
Sun Nov 15 00:00:00 EST 2020
IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity.
Innate immunity
Karimi Y,Giles EC,Vahedi F,Chew MV,Nham T,Loukov D,Lee AJ,Bowdish DM,Ashkar AA
56-5321 was used in Flow cytometry/Cell sorting to elucidate differences in the effect of type I IFN signalling on macrophage functioning in the context of TLR activation.
Wed Apr 01 00:00:00 EDT 2020
IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity.
Innate immunity
Karimi Y,Giles EC,Vahedi F,Chew MV,Nham T,Loukov D,Lee AJ,Bowdish DM,Ashkar AA
56-5321 was used in Flow cytometry/Cell sorting to elucidate differences in the effect of type I IFN signalling on macrophage functioning in the context of TLR activation.
Wed Apr 01 00:00:00 EDT 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications
Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G
56-5321 was used in Flow cytometry/Cell sorting to study the mechanism that controls the development of αβ T cell lineages in the thymus.
Mon May 04 00:00:00 EDT 2020
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications
Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G
56-5321 was used in Flow cytometry/Cell sorting to study the mechanism that controls the development of αβ T cell lineages in the thymus.
Mon May 04 00:00:00 EDT 2020
Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis.
JCI insight
Lu S,Jolly AJ,Strand KA,Dubner AM,Mutryn MF,Moulton KS,Nemenoff RA,Majesky MW,Weiser-Evans MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Immunomodulatory Effects of Recombinant Mycobacterium smegmatis Expressing Antigen-85B Epitopes in Infected J774A.1 Murine Macrophages.
Pathogens (Basel, Switzerland)
Kadir NA,Acosta A,Sarmiento ME,Norazmi MN
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Sun Nov 29 00:00:00 EST 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Optimized Protocol for Isolation of Small Extracellular Vesicles from Human and Murine Lymphoid Tissues.
International journal of molecular sciences
Bordas M,Genard G,Ohl S,Nessling M,Richter K,Roider T,Dietrich S,Maaß KK,Seiffert M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Optimized Protocol for Isolation of Small Extracellular Vesicles from Human and Murine Lymphoid Tissues.
International journal of molecular sciences
Bordas M,Genard G,Ohl S,Nessling M,Richter K,Roider T,Dietrich S,Maaß KK,Seiffert M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.
Stem cell research & therapy
Martins L,Gallo CC,Honda TSB,Alves PT,Stilhano RS,Rosa DS,Koh TJ,Han SW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Nov 06 00:00:00 EST 2020
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications
Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Aug 11 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
56-5321 was used in flow cytometry to analyse the myeloid populations in various mouse tissues by flow cytometry.
Fri Jun 19 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
56-5321 was used in flow cytometry to analyse the myeloid populations in various mouse tissues by flow cytometry.
Fri Jun 19 00:00:00 EDT 2020
RON Expression Mediates Lipopolysaccharide-Mediated Dendritic Cell Maturation via March-I.
Frontiers in cellular and infection microbiology
Huang L,Fang X,Zhang X,Wu W,Yao H,Fang Q
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunoprecipitation
Sun Apr 02 00:00:00 EDT 2023
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
eLife
Kim EH,Woodruff MC,Grigoryan L,Maier B,Lee SH,Mandal P,Cortese M,Natrajan MS,Ravindran R,Ma H,Merad M,Gitlin AD,Mocarski ES,Jacob J,Pulendran B
56-5321 was used in Flow cytometry/Cell sorting to demonstrate that squalene emulsion-based vaccine adjuvants induce antigen-specific CD8 T cell and antibody responses, through RIPK3-dependent and-independent pathways, respectively.
Tue Jun 09 00:00:00 EDT 2020
CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner.
Theranostics
Zhang QF,Li J,Jiang K,Wang R,Ge JL,Yang H,Liu SJ,Jia LT,Wang L,Chen BL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer.
Scientific reports
Moufarrij S,Srivastava A,Gomez S,Hadley M,Palmer E,Austin PT,Chisholm S,Diab N,Roche K,Yu A,Li J,Zhu W,Lopez-Acevedo M,Villagra A,Chiappinelli KB
56-5321-82 was used in Flow Cytometry to find that combining DNMTi and HDAC6i results in an amplified type I interferon response, leading to increased cytokine and chemokine expression and higher expression of the MHC I antigen presentation complex in human and mouse ovarian cancer cell lines.
Wed Feb 26 00:00:00 EST 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
56-5321-82 was used in Flow Cytometry to show drainage of gut-draining lymph nodes can resolve conflicting tolerogenic and inflammatory intestinal responses by encouraging antigen targeting to specific gut segments.
Wed May 01 00:00:00 EDT 2019
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.
Immunity
Bonnardel J,T'Jonck W,Gaublomme D,Browaeys R,Scott CL,Martens L,Vanneste B,De Prijck S,Nedospasov SA,Kremer A,Van Hamme E,Borghgraef P,Toussaint W,De Bleser P,Mannaerts I,Beschin A,van Grunsven LA,Lambrecht BN,Taghon T,Lippens S,Elewaut D,Saeys Y,Guilliams M
56-5321-82 was used in Flow Cytometry to show that the Kupffer cell niche is composed of stellate cells, hepatocytes, and endothelial cells that together imprint the liver-specific macrophage identity.
Tue Oct 15 00:00:00 EDT 2019
Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.
Immunity
Dmitrieva-Posocco O,Dzutsev A,Posocco DF,Hou V,Yuan W,Thovarai V,Mufazalov IA,Gunzer M,Shilovskiy IP,Khaitov MR,Trinchieri G,Waisman A,Grivennikov SI
56-5321-82 was used in Flow Cytometry to examine the impact of IL-1 signaling, a key regulator of the IL-17 pathway, in different cell types within the CRC microenvironment.
Tue Jan 15 00:00:00 EST 2019
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.
Cell host & microbe
Leech JM,Dhariwala MO,Lowe MM,Chu K,Merana GR,Cornuot C,Weckel A,Ma JM,Leitner EG,Gonzalez JR,Vasquez KS,Diep BA,Scharschmidt TC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Dec 11 00:00:00 EST 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
The Journal of experimental medicine
Etzerodt A,Tsalkitzi K,Maniecki M,Damsky W,Delfini M,Baudoin E,Moulin M,Bosenberg M,Graversen JH,Auphan-Anezin N,Moestrup SK,Lawrence T
56-5321 was used in Flow cytometry/Cell sorting to study the immune-suppressive function for CD163+ TAM in melanoma that is independent of the PD-1/PD-L1 axis.
Mon Oct 07 00:00:00 EDT 2019
IGF1 Treatment Improves Cardiac Remodeling after Infarction by Targeting Myeloid Cells.
Molecular therapy : the journal of the American Society of Gene Therapy
Heinen A,Nederlof R,Panjwani P,Spychala A,Tschaidse T,Reffelt H,Boy J,Raupach A,Gödecke S,Petzsch P,Köhrer K,Grandoch M,Petz A,Fischer JW,Alter C,Vasilevska J,Lang P,Gödecke A
56-5321 was used in Flow cytometry/Cell sorting to demonstrate that short-term insulin-like growth factor 1 treatment for 3 days after acute myocardial infarction improved cardiac function after 1 and 4 weeks.
Wed Jan 02 00:00:00 EST 2019
STING pathway stimulation results in a differentially activated innate immune phenotype associated with low nitric oxide and enhanced antibody titers in young and aged mice.
Vaccine
Darling RJ,Senapati S,Kelly SM,Kohut ML,Narasimhan B,Wannemuehler MJ
56-5321-82 was used in Flow Cytometry to demonstrate that cyclic dinucleotides induce differential innate activation and enhance vaccine induced antibody responses in both young and aged mice.
Mon May 06 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
Intravitreal injection of adenosine A2A receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice.
Scientific reports
Aires ID,Madeira MH,Boia R,Rodrigues-Neves AC,Martins JM,Ambrósio AF,Santiago AR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Wed Nov 20 00:00:00 EST 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.
Cell reports
Shikatani EA,Besla R,Ensan S,Upadhye A,Khyzha N,Li A,Emoto T,Chiu F,Degousee N,Moreau JM,Perry HM,Thayaparan D,Cheng HS,Pacheco S,Smyth D,Noyan H,Zavitz CCJ,Bauer CMT,Hilgendorf I,Libby P,Swirski FK,Gommerman JL,Fish JE,Stampfli MR,Cybulsky MI,Rubin BB,Paige CJ,Bender TP,McNamara CA,Husain M,Robbins CS
56-5321-82 was used in Flow Cytometry to identify the nuclear transcription factor c-Myb as an important mediator of atherosclerotic disease in mice.
Tue May 21 00:00:00 EDT 2019
Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production.
Frontiers in immunology
Kiss MG,Ozsvár-Kozma M,Porsch F,Göderle L,Papac-Miličević N,Bartolini-Gritti B,Tsiantoulas D,Pickering MC,Binder CJ
56-5321-82 was used in Flow Cytometry to indicate that CFH, through its function as a complement repressor, acts as a negative regulator of BCR signaling and limits autoimmunity.
Tue Oct 13 00:00:00 EDT 2020
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5.
The Journal of experimental medicine
Buxadé M,Huerga Encabo H,Riera-Borrull M,Quintana-Gallardo L,López-Cotarelo P,Tellechea M,Martínez-Martínez S,Redondo JM,Martín-Caballero J,Flores JM,Bosch E,Rodríguez-Fernández JL,Aramburu J,López-Rodríguez C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Nov 05 00:00:00 EST 2018
The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes.
The EMBO journal
Fletcher K,Ulferts R,Jacquin E,Veith T,Gammoh N,Arasteh JM,Mayer U,Carding SR,Wileman T,Beale R,Florey O
56-5321 was used in Flow cytometry/Cell sorting to demonstrate activation of non-canonical autophagy dependent on the WD40 CTD during influenza A virus infection.
Thu Feb 15 00:00:00 EST 2018
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Glia
Kim S,Bielawski J,Yang H,Kong Y,Zhou B,Li J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunocytochemistry
Thu Mar 01 00:00:00 EST 2018
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Glia
Kim S,Bielawski J,Yang H,Kong Y,Zhou B,Li J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunocytochemistry
Thu Mar 01 00:00:00 EST 2018
Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
Frontiers in aging neuroscience
Klein B,Mrowetz H,Barker CM,Lange S,Rivera FJ,Aigner L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Thu Oct 01 00:00:00 EDT 2020
Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
Frontiers in aging neuroscience
Klein B,Mrowetz H,Barker CM,Lange S,Rivera FJ,Aigner L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Thu Oct 01 00:00:00 EDT 2020
SunRiSE - measuring translation elongation at single-cell resolution by means of flow cytometry.
Journal of cell science
Argüello RJ,Reverendo M,Mendes A,Camosseto V,Torres AG,Ribas de Pouplana L,van de Pavert SA,Gatti E,Pierre P
56-5321 was used in Flow cytometry/Cell sorting to demonstrate that, in mouse embryonic fibroblasts, eEF2 phosphorylation by eEF2 kinase (eEF2K) mostly affects translation engagement, but has a surprisingly small effect on elongation, except after proteotoxic stress induction.
Thu May 31 00:00:00 EDT 2018
FACS isolation of live mouse eosinophils at high purity via a protocol that does not target Siglec F.
Journal of immunological methods
Geslewitz WE,Percopo CM,Rosenberg HF
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
Nature communications
Bonacina F,Coe D,Wang G,Longhi MP,Baragetti A,Moregola A,Garlaschelli K,Uboldi P,Pellegatta F,Grigore L,Da Dalt L,Annoni A,Gregori S,Xiao Q,Caruso D,Mitro N,Catapano AL,Marelli-Berg FM,Norata GD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Aug 06 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Lin-CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade.
Nature communications
Flores CT,Wildes TJ,Drake JA,Moore GL,Dean BD,Abraham RS,Mitchell DA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Oct 17 00:00:00 EDT 2018
Macrophages orchestrate breast cancer early dissemination and metastasis.
Nature communications
Linde N,Casanova-Acebes M,Sosa MS,Mortha A,Rahman A,Farias E,Harper K,Tardio E,Reyes Torres I,Jones J,Condeelis J,Merad M,Aguirre-Ghiso JA
56-5321 was used in Flow cytometry/Cell sorting to show that, in pre-malignant lesions, CCL2 produced by cancer cells and myeloid cells attracts CD206+/Tie2+macrophages and induces Wnt-1 upregulation that in turn downregulates E-cadherin junctions in the HER2+early cancer cells.
Tue Jan 02 00:00:00 EST 2018
Hyaluronidase inhibits reactive adipogenesis and inflammation of colon and skin.
JCI insight
Dokoshi T,Zhang LJ,Nakatsuji T,Adase CA,Sanford JA,Paladini RD,Tanaka H,Fujiya M,Gallo RL
56-5321 was used in Flow cytometry/Cell sorting to suggest hyaluronidase plays an important role in reactive adipogenesis and host defense after injury.
Fri Nov 02 00:00:00 EDT 2018
Nippostrongylus brasiliensis infection leads to impaired reference memory and myeloid cell interference.
Scientific reports
Brombacher TM,De Gouveia KS,Cruywagen L,Makena N,Booley F,Tamgue O,Brombacher F
56-5321 was used in Flow cytometry/Cell sorting to identify cognitive changes during Nippostrongylus brasiliensis infection.
Tue Feb 13 00:00:00 EST 2018
Early Resistance of Non-virulent Mycobacterial Infection in C57BL/6 Mice Is Associated With Rapid Up-Regulation of Antimicrobial Cathelicidin Camp.
Frontiers in immunology
Adam L,López-González M,Björk A,Pålsson S,Poux C,Wahren-Herlenius M,Fernández C,Spetz AL
56-5321 was used in Flow cytometry/Cell sorting to assess the early innate immune events locally in the lungs to identify factors that may contribute to the control of non-virulent mycobacterial burden.
Wed Sep 18 00:00:00 EDT 2019
Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
Nature
Camell CD,Sander J,Spadaro O,Lee A,Nguyen KY,Wing A,Goldberg EL,Youm YH,Brown CW,Elsworth J,Rodeheffer MS,Schultze JL,Dixit VD
56-5321 was used in Flow cytometry/Cell sorting to show that adipose tissue macrophages regulate the age-related reduction in adipocyte lipolysis in mice by lowering the bioavailability of noradrenaline.
Thu Oct 05 00:00:00 EDT 2017
Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.
Cell
Berry MR,Mathews RJ,Ferdinand JR,Jing C,Loudon KW,Wlodek E,Dennison TW,Kuper C,Neuhofer W,Clatworthy MR
56-5321-82 was used in Flow Cytometry to reveal a critical accessory role for the homeostatic function of a vital organ in optimizing tissue defense.
Thu Aug 24 00:00:00 EDT 2017
Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections.
Immunity
Roquilly A,McWilliam HEG,Jacqueline C,Tian Z,Cinotti R,Rimbert M,Wakim L,Caminschi I,Lahoud MH,Belz GT,Kallies A,Mintern JD,Asehnoune K,Villadangos JA
56-5321 was used in Flow cytometry/Cell sorting to study the mechanisms underlying sepsis- and trauma-induced immunosuppression, reveal prognostic markers of susceptibility to secondary infections and identify potential targets for therapeutic intervention.
Tue Jul 18 00:00:00 EDT 2017
Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.
Immunity
Goudot C,Coillard A,Villani AC,Gueguen P,Cros A,Sarkizova S,Tang-Huau TL,Bohec M,Baulande S,Hacohen N,Amigorena S,Segura E
56-5321 was used in Flow cytometry/Cell sorting to elucidate the role of the aryl hydrocarbon receptor as a molecular switch for monocyte fate specification in response to micro-environmental factors.
Tue Sep 19 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Mucosal immunology
Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
56-5321 was used in Flow cytometry/Cell sorting to show how CCR2(-) and CCR2(+) corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Fri Sep 01 00:00:00 EDT 2017
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Journal of immunology (Baltimore, Md. : 1950)
Dolina JS,Cechova S,Rudy CK,Sung SJ,Tang WW,Lee J,Hahn YS,Le TH
56-5321 was used in Flow cytometry/Cell sorting to identify the functional role of collectrin in the liver.
Wed Mar 15 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Frontiers in cellular neuroscience
Cruz SA,Hari A,Qin Z,Couture P,Huang H,Lagace DC,Stewart AFR,Chen HH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis.
PloS one
McDonald LT,Johnson SD,Russell DL,Young MRI,LaRue AC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Sep 25 00:00:00 EDT 2017
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Mon Feb 06 00:00:00 EST 2017
CD24 induces changes to the surface receptors of B cell microvesicles with variable effects on their RNA and protein cargo.
Scientific reports
Ayre DC,Chute IC,Joy AP,Barnett DA,Hogan AM,Grüll MP,Peña-Castillo L,Lang AS,Lewis SM,Christian SL
56-5321 was used in Flow cytometry/Cell sorting to perform a systematic characterisation of B cell microvesicles released from WEHI-231 B lymphoma cells in response to CD24 stimulation.
Thu Aug 17 00:00:00 EDT 2017
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells.
Nature communications
Maschalidi S,Nunes-Hasler P,Nascimento CR,Sallent I,Lannoy V,Garfa-Traore M,Cagnard N,Sepulveda FE,Vargas P,Lennon-Duménil AM,van Endert P,Capiod T,Demaurex N,Darrasse-Jèze G,Manoury B
56-5321 was used in Flow cytometry/Cell sorting to show that UNC93B1 interacts with the calcium sensor STIM1 in the endoplasmic reticulum, a critical step for STIM1 oligomerisation and activation.
Tue Nov 21 00:00:00 EST 2017
IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis.
Scientific reports
Peshkova IO,Fatkhullina AR,Mikulski Z,Ley K,Koltsova EK
56-5321 was used in Flow cytometry/Cell sorting to study the role of IL-27R in controlling myeloid cell accumulation and activation in atherosclerosis.
Tue May 23 00:00:00 EDT 2017
Microglial brain region-dependent diversity and selective regional sensitivities to aging.
Nature neuroscience
Grabert K,Michoel T,Karavolos MH,Clohisey S,Baillie JK,Stevens MP,Freeman TC,Summers KM,McColl BW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Glia
Guglielmetti C,Le Blon D,Santermans E,Salas-Perdomo A,Daans J,De Vocht N,Shah D,Hoornaert C,Praet J,Peerlings J,Kara F,Bigot C,Mai Z,Goossens H,Hens N,Hendrix S,Verhoye M,Planas AM,Berneman Z,van der Linden A,Ponsaerts P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Thu Dec 01 00:00:00 EST 2016
Microglia are less pro-inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus.
Glia
Vinet J,Vainchtein ID,Spano C,Giordano C,Bordini D,Curia G,Dominici M,Boddeke HW,Eggen BJ,Biagini G
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Mon Aug 01 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis.
Laboratory investigation; a journal of technical methods and pathology
Connor AL,Kelley PM,Tempero RM
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Tue Mar 01 00:00:00 EST 2016
Brucella discriminates between mouse dendritic cell subsets upon in vitro infection.
Virulence
Papadopoulos A,Gagnaire A,Degos C,de Chastellier C,Gorvel JP
56-5321 was used in Flow cytometry/Cell sorting to compare Brucella interaction with several in vitro bone marrow-derived dendritic cell models.
Thu Oct 20 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
TLR Tolerance as a Treatment for Central Nervous System Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Anstadt EJ,Fujiwara M,Wasko N,Nichols F,Clark RB
56-5321 was used in Flow cytometry/Cell sorting to assess the role of Toll-like receptor 2 signalling in central nervous system autoimmune diseases, and the potential of inducing TLR tolerance to ameliorate disease.
Thu Sep 15 00:00:00 EDT 2016
Effects of ketanserin on experimental colitis in mice and macrophage function.
International journal of molecular medicine
Xiao J,Shao L,Shen J,Jiang W,Feng Y,Zheng P,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
American journal of translational research
Wang H,Hu W,Liang Z,Zeng L,Li J,Yan H,Yang P,Liu Z,Wang L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Evaluation of the irritancy and hypersensitivity potential following topical application of didecyldimethylammonium chloride.
Journal of immunotoxicology
Anderson SE,Shane H,Long C,Lukomska E,Meade BJ,Marshall NB
56-5321 was used in Flow cytometry/Cell sorting to investigate the irritancy and hypersensivity potential of didecyldimethylammonium chloride (DDAC).
Fri Jul 01 00:00:00 EDT 2016
Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.
Frontiers in cellular neuroscience
Klein B,Mrowetz H,Thalhamer J,Scheiblhofer S,Weiss R,Aigner L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Fri Jul 22 00:00:00 EDT 2016
Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.
Aging
McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Epidermal RAF prevents allergic skin disease.
eLife
Raguz J,Jeric I,Niault T,Nowacka JD,Kuzet SE,Rupp C,Fischer I,Biggi S,Borsello T,Baccarini M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model.
Journal of neuroinflammation
Le Blon D,Guglielmetti C,Hoornaert C,Quarta A,Daans J,Dooley D,Lemmens E,Praet J,De Vocht N,Reekmans K,Santermans E,Hens N,Goossens H,Verhoye M,Van der Linden A,Berneman Z,Hendrix S,Ponsaerts P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Wed Nov 09 00:00:00 EST 2016
Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration.
eLife
Lopes Pinheiro MA,Kamermans A,Garcia-Vallejo JJ,van Het Hof B,Wierts L,O'Toole T,Boeve D,Verstege M,van der Pol SM,van Kooyk Y,de Vries HE,Unger WW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Scientific reports
Ying W,Tseng A,Chang RC,Wang H,Lin YL,Kanameni S,Brehm T,Morin A,Jones B,Splawn T,Criscitiello M,Golding MC,Bazer FW,Safe S,Zhou B
56-5321 was used in Flow cytometry/Cell sorting to demonstrate a role for miR-150 in regulating B cell functions in adipose tissue.
Mon Feb 01 00:00:00 EST 2016
Proteomic Analysis of Excretory-Secretory Products of Mesocestoides corti Metacestodes Reveals Potential Suppressors of Dendritic Cell Functions.
PLoS neglected tropical diseases
Vendelova E,Camargo de Lima J,Lorenzatto KR,Monteiro KM,Mueller T,Veepaschit J,Grimm C,Brehm K,Hrčková G,Lutz MB,Ferreira HB,Nono JK
56-5321 was used in Flow cytometry/Cell sorting to study the immunomodulatory effects of excretory-secretory products derived from M. corti tetrathyridia.
Sat Oct 01 00:00:00 EDT 2016
Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.
Scientific reports
Li SX,Barrett BS,Guo K,Kassiotis G,Hasenkrug KJ,Dittmer U,Gibbert K,Santiago ML
56-5321 was used in Flow cytometry/Cell sorting to investigate the role of Tetherin in counteracting retrovirus replication in vivo.
Fri Feb 05 00:00:00 EST 2016
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
eLife
Pearson C,Thornton EE,McKenzie B,Schaupp AL,Huskens N,Griseri T,West N,Tung S,Seddon BP,Uhlig HH,Powrie F
56-5321 was used in Immunofluorescence to investigate how a small population of innate lymphoid cells (ILCs) has large effects on immune homeostasis, showing that ILC3s produce GM-CSF to orchestrate acute intestinal inflammation.
Mon Jan 18 00:00:00 EST 2016
Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice.
PloS one
Schmidt D,Peterlik D,Reber SO,Lechner A,Männel DN
56-5321 was used in Flow cytometry/Cell sorting to observe the immunological effects of chronic psychosocial stress in mice.
Fri Aug 18 00:00:00 EDT 2017
Dendritic cell-derived nitric oxide inhibits the differentiation of effector dendritic cells.
Oncotarget
Si C,Zhang R,Wu T,Lu G,Hu Y,Zhang H,Xu F,Wei P,Chen K,Tang H,Yeretssian G,Xiong H
56-5321 was used in Flow cytometry/Cell sorting to demonstrate that DC-derived nitric oxide restrains effector DC development to treat autoimmune and inflammatory diseases.
Tue Nov 15 00:00:00 EST 2016
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Sep 14 00:00:00 EDT 2015
Benefits of Neuronal Preferential Systemic Gene Therapy for Neurotransmitter Deficiency.
Molecular therapy : the journal of the American Society of Gene Therapy
Lee NC,Muramatsu S,Chien YH,Liu WS,Wang WH,Cheng CH,Hu MK,Chen PW,Tzen KY,Byrne BJ,Hwu WL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2015
The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
The Journal of investigative dermatology
Sparber F,Tripp CH,Komenda K,Scheffler JM,Clausen BE,Huber LA,Romani N,Stoitzner P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Brucella CβG induces a dual pro- and anti-inflammatory response leading to a transient neutrophil recruitment.
Virulence
Degos C,Gagnaire A,Banchereau R,Moriyón I,Gorvel JP
56-5321 was used in Flow cytometry/Cell sorting to study the consequence of dual pro- and anti-inflammatory signals triggered by Brucella Β-1,2 cyclic glucan.
Tue Feb 09 00:00:00 EST 2016
Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
van Blijswijk J,Schraml BU,Rogers NC,Whitney PG,Zelenay S,Acton SE,Reis e Sousa C
56-5321 was used in Flow cytometry/Cell sorting to report that mice in which DTR is expressed on DCs display lymph node hypocellularity and reduced frequency of DCs in the same organs.
Thu Jan 01 00:00:00 EST 2015
Dynamics and Transcriptomics of Skin Dendritic Cells and Macrophages in an Imiquimod-Induced, Biphasic Mouse Model of Psoriasis.
Journal of immunology (Baltimore, Md. : 1950)
Terhorst D,Chelbi R,Wohn C,Malosse C,Tamoutounour S,Jorquera A,Bajenoff M,Dalod M,Malissen B,Henri S
56-5321 was used in Flow cytometry/Cell sorting to develop and characterise an improved mouse model of psoriasis using imiquimod, showing that the dynamics and transcriptomics of skin dendritic cells and macrophages are similar to those seen in human pathology.
Sun Nov 15 00:00:00 EST 2015
Triclosan Induces Thymic Stromal Lymphopoietin in Skin Promoting Th2 Allergic Responses.
Toxicological sciences : an official journal of the Society of Toxicology
Marshall NB,Lukomska E,Long CM,Kashon ML,Sharpnack DD,Nayak AP,Anderson KL,Jean Meade B,Anderson SE
56-5321 was used in Flow cytometry/Cell sorting to examine the effects of dermal triclosan exposure on the skin and lymph nodes of mice and in a human skin model to identify mechanisms for augmenting allergic responses.
Tue Sep 01 00:00:00 EDT 2015
Genetically Modified Live Attenuated Leishmania donovani Parasites Induce Innate Immunity through Classical Activation of Macrophages That Direct the Th1 Response in Mice.
Infection and immunity
Bhattacharya P,Dey R,Dagur PK,Kruhlak M,Ismail N,Debrabant A,Joshi AB,Akue A,Kukuruga M,Takeda K,Selvapandiyan A,McCoy JP,Nakhasi HL
56-5321 was used in Flow cytometry/Cell sorting to suggest that infection with live attenuated parasites promotes a state of classical activation (M1 dominant) in macrophages that leads to the generation of protective Th1 responses in BALB/c mice.
Thu Oct 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Tue Aug 18 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Tue Aug 18 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Tue Aug 18 00:00:00 EDT 2015
Gene expression profiling of the Peyer's patch mononuclear phagocyte system.
Genomics data
Bonnardel J,Da Silva C,Masse M,Montañana-Sanchis F,Gorvel JP,Lelouard H
56-5321 was used in Flow cytometry/Cell sorting to investigate the gene expression profile of the Peyer's patch mononuclear phagocyte system.
Tue Sep 01 00:00:00 EDT 2015
Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization.
Nature communications
Lu G,Zhang R,Geng S,Peng L,Jayaraman P,Chen C,Xu F,Yang J,Li Q,Zheng H,Shen K,Wang J,Liu X,Wang W,Zheng Z,Qi CF,Si C,He JC,Liu K,Lira SA,Sikora AG,Li L,Xiong H
56-5321 was used in Flow cytometry/Cell sorting to show that iNOS-deficient mice display enhanced classically activated M1 macrophage polarization without major effects on alternatively activated M2 macrophages.
Fri Mar 27 00:00:00 EDT 2015
Apoptotic cell clearance of Leishmania major-infected neutrophils by dendritic cells inhibits CD8⁺ T-cell priming in vitro by Mer tyrosine kinase-dependent signaling.
Cell death & disease
Ribeiro-Gomes FL,Romano A,Lee S,Roffê E,Peters NC,Debrabant A,Sacks D
56-5321 was used in Flow cytometry/Cell sorting to define the clearance of infected neutrophils by dendritic cells as central to the early immune evasion strategies of L. major.
Thu Dec 10 00:00:00 EST 2015
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.
Nature
Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Thu Feb 27 00:00:00 EST 2014
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Nature
Schulz MD,Atay C,Heringer J,Romrig FK,Schwitalla S,Aydin B,Ziegler PK,Varga J,Reindl W,Pommerenke C,Salinas-Riester G,Böck A,Alpert C,Blaut M,Polson SC,Brandl L,Kirchner T,Greten FR,Polson SW,Arkan MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Oct 23 00:00:00 EDT 2014
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.
The Journal of experimental medicine
Madireddi S,Eun SY,Lee SW,Nemčovičová I,Mehta AK,Zajonc DM,Nishi N,Niki T,Hirashima M,Croft M
56-5321 was used in Flow cytometry/Cell sorting to delineate the mechanism of action of agonist anti-4-1BB in suppressing autoimmune and allergic inflammation.
Mon Jun 30 00:00:00 EDT 2014
CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.
The Journal of experimental medicine
Longman RS,Diehl GE,Victorio DA,Huh JR,Galan C,Miraldi ER,Swaminath A,Bonneau R,Scherl EJ,Littman DR
56-5321 was used in Flow cytometry/Cell sorting to study the role of CX3CR1+ mononuclear phagocytes in the development of colitis and disease progression following Citrobacter rodentium infection.
Mon Jul 28 00:00:00 EDT 2014
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
The Journal of experimental medicine
Weber GF,Chousterman BG,Hilgendorf I,Robbins CS,Theurl I,Gerhardt LM,Iwamoto Y,Quach TD,Ali M,Chen JW,Rothstein TL,Nahrendorf M,Weissleder R,Swirski FK
56-5321 was used in Flow cytometry/Cell sorting to study the migration and release of immunoglobulin M by B1a B cells in response to lung infection.
Mon Jun 02 00:00:00 EDT 2014
Targeting intestinal inflammation with CD98 siRNA/PEI-loaded nanoparticles.
Molecular therapy : the journal of the American Society of Gene Therapy
Laroui H,Geem D,Xiao B,Viennois E,Rakhya P,Denning T,Merlin D
56-5321 was used in Flow cytometry/Cell sorting to show that CD98 was effectively down-regulated in the intestinal epithelial cells and intestinal macrophages of treated mice.
Wed Jan 01 00:00:00 EST 2014
C/EBPβ expression is an independent predictor of overall survival in breast cancer patients by MHCII/CD4-dependent mechanism of metastasis formation.
Oncogenesis
Kurzejamska E,Johansson J,Jirström K,Prakash V,Ananthaseshan S,Boon L,Fuxe J,Religa P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Mon Nov 03 00:00:00 EST 2014
Helping themselves: optimal virus-specific CD4 T cell responses require help via CD4 T cell licensing of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Olson MR,Seah SG,Cullen J,Greyer M,Edenborough K,Doherty PC,Bedoui S,Lew AM,Turner SJ
56-5321 was used in Flow cytometry/Cell sorting to investigate whether induction of CD4(+) Th responses postinfection are also dependent on CD4(+) T cell help.
Mon Dec 01 00:00:00 EST 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunoprecipitation
Wed Jan 01 00:00:00 EST 2014
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunoprecipitation
Wed Jan 01 00:00:00 EST 2014
Carbohydrate-functionalized nanovaccines preserve HIV-1 antigen stability and activate antigen presenting cells.
Journal of biomaterials science. Polymer edition
Vela Ramirez JE,Roychoudhury R,Habte HH,Cho MW,Pohl NL,Narasimhan B
56-5321 was used in Flow cytometry/Cell sorting to develop an optimised process for carbohydrate functionalisation of HIV-1 antigen-loaded polyanhydride nanoparticles, and evaluate the effect of these nanoparticles on dendritic cell activation.
Mon Apr 20 00:00:00 EDT 2015
Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis.
Infection and immunity
Christian DA,Koshy AA,Reuter MA,Betts MR,Boothroyd JC,Hunter CA
56-5321 was used in Flow cytometry/Cell sorting to study the cell types which secrete IL-12p40 during Toxoplasma gondii infection.
Wed Oct 01 00:00:00 EDT 2014
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
PloS one
Assi H,Espinosa J,Suprise S,Sofroniew M,Doherty R,Zamler D,Lowenstein PR,Castro MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Jan 23 00:00:00 EST 2015
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
PloS one
Assi H,Espinosa J,Suprise S,Sofroniew M,Doherty R,Zamler D,Lowenstein PR,Castro MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Jan 23 00:00:00 EST 2015
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis.
PloS one
Wenzel UA,Magnusson MK,Rydström A,Jonstrand C,Hengst J,Johansson ME,Velcich A,Öhman L,Strid H,Sjövall H,Hansson GC,Wick MJ
56-5321 was used in Flow cytometry/Cell sorting to support the comparison of colon immune cell compartment in Muc2-/- mice and ulcerative colitis patients as an ulcerative colitis model.
Thu Mar 12 00:00:00 EDT 2015
Modulation of innate antigen-presenting cell function by pre-patent schistosome infection.
PLoS neglected tropical diseases
Ferragine CE,Walls CD,Davies SJ
56-5321 was used in Flow cytometry/Cell sorting to show that CD11b+ cells exposed to prepatent schistosome infection are impaired in their ability to stimulate CD4+ T cells.
Wed Aug 28 00:00:00 EDT 2013
Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.
Immunity
Kinnebrew MA,Buffie CG,Diehl GE,Zenewicz LA,Leiner I,Hohl TM,Flavell RA,Littman DR,Pamer EG
56-5321 was used in Flow cytometry/Cell sorting to demonstrate cytokine expression by certain DCs drives IL-22-dependent RegIIIγ production for protection from bacterial colonisation.
Fri Feb 24 00:00:00 EST 2012
Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance.
Immunity
Hadeiba H,Lahl K,Edalati A,Oderup C,Habtezion A,Pachynski R,Nguyen L,Ghodsi A,Adler S,Butcher EC
56-5321 was used in Flow cytometry/Cell sorting to explore the mechanisms underlying the contribution to immune tolerance conducted by peripheral dendritic cells.
Fri Mar 23 00:00:00 EDT 2012
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood
He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Thu Oct 11 00:00:00 EDT 2012
Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis.
The Journal of clinical investigation
Koltsova EK,Garcia Z,Chodaczek G,Landau M,McArdle S,Scott SR,von Vietinghoff S,Galkina E,Miller YI,Acton ST,Ley K
56-5321 was used in Flow cytometry/Cell sorting to conclude that antigen presentation to CD4+ cells causes local T cell activation and the production of proinflammatory cytokines.
Sat Sep 01 00:00:00 EDT 2012
Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response.
PLoS pathogens
Ribeiro-Gomes FL,Peters NC,Debrabant A,Sacks DL
56-5321 was used in Flow cytometry/Cell sorting to study how exploitation of immunosuppressive effects by L.major following rapid uptake by skin neutrophils allows inhibition of acquired resistance.
Wed Feb 01 00:00:00 EST 2012
CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization.
Journal of immunology (Baltimore, Md. : 1950)
Langlet C,Tamoutounour S,Henri S,Luche H,Ardouin L,Grégoire C,Malissen B,Guilliams M
56-5321 was used in Flow cytometry/Cell sorting to define the distinct DC subsets that reside in skeletal muscles and identify their migratory counterparts in draining LNs.
Wed Feb 15 00:00:00 EST 2012
Evaluation of recombinant Leishmania polyprotein plus glucopyranosyl lipid A stable emulsion vaccines against sand fly-transmitted Leishmania major in C57BL/6 mice.
Journal of immunology (Baltimore, Md. : 1950)
Peters NC,Bertholet S,Lawyer PG,Charmoy M,Romano A,Ribeiro-Gomes FL,Stamper LW,Sacks DL
56-5321 was used in Flow cytometry/Cell sorting to assess the immunity generated by recombinant Leishmania polyprotein with GLA vaccination following challenge with L. major.
Thu Nov 15 00:00:00 EST 2012
Preferential colonization of metastases by oncolytic vaccinia virus strain GLV-1h68 in a human PC-3 prostate cancer model in nude mice.
PloS one
Donat U,Weibel S,Hess M,Stritzker J,Härtl B,Sturm JB,Chen NG,Gentschev I,Szalay AA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunofluorescence
Tue May 07 00:00:00 EDT 2013
Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells.
PloS one
Cheng CC,Lian WS,Hsiao FS,Liu IH,Lin SP,Lee YH,Chang CC,Xiao GY,Huang HY,Cheng CF,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2012
Shape-based tracking allows functional discrimination of two immune cell subsets expressing the same fluorescent tag in mouse lung explant.
PloS one
Fiole D,Touvrey C,Quesnel-Hellmann A,Douady J,Tournier JN
56-5321 was used in Flow cytometry/Cell sorting to demonstrate a novel method for discrimination between DCs and closely related cell lineages in mouse lungs.
Fri Nov 30 00:00:00 EST 2012
Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen.
Blood
McGaha TL,Chen Y,Ravishankar B,van Rooijen N,Karlsson MC
56-5321 was used in Flow cytometry/Cell sorting to support the hypothesis that MZMs are central in the clearance of apoptotic cells to minimize the immunogenicity of autoantigens.
Thu May 19 00:00:00 EDT 2011
CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice.
The Journal of clinical investigation
Medina-Contreras O,Geem D,Laur O,Williams IR,Lira SA,Nusrat A,Parkos CA,Denning TL
56-5321 was used in Flow cytometry/Cell sorting to investigate the relative contributions of different APC populations in IBD, showing that CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses.
Thu Dec 01 00:00:00 EST 2011
The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
European journal of immunology
Luche H,Ardouin L,Teo P,See P,Henri S,Merad M,Ginhoux F,Malissen B
56-5321 was used in Flow cytometry/Cell sorting to provide evidence that myeloid-restricted progenitors generate the whole constellation of DCs present in the body, including the thymus.
Mon Aug 01 00:00:00 EDT 2011
Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization.
Journal of immunology (Baltimore, Md. : 1950)
Denning TL,Norris BA,Medina-Contreras O,Manicassamy S,Geem D,Madan R,Karp CL,Pulendran B
56-5321 was used in Flow cytometry/Cell sorting to systematically evaluate the phenotype, function and regional localisation of intestinal APCs.
Fri Jul 15 00:00:00 EDT 2011
Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery.
Frontiers in immunology
Bouvier I,Jusforgues-Saklani H,Lim A,Lemaître F,Lemercier B,Auriau C,Nicola MA,Leroy S,Law HK,Bandeira A,Moon JJ,Bousso P,Albert ML
56-5321 was used in Flow cytometry/Cell sorting to highlight the importance of considering the timing and persistence of antigen presentation for vaccination.
Thu Aug 23 00:00:00 EDT 2012
Disrupted lymph node and splenic stroma in mice with induced inflammatory melanomas is associated with impaired recruitment of T and dendritic cells.
PloS one
Soudja SM,Henri S,Mello M,Chasson L,Mas A,Wehbe M,Auphan-Anezin N,Leserman L,Van den Eynde B,Schmitt-Verhulst AM
56-5321 was used in Flow cytometry/Cell sorting to study the influence of tumour-associated inflammation on secondary lymphoid organ organisation.
Mon Dec 05 00:00:00 EST 2011
Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme.
Gastroenterology
Lelouard H,Henri S,De Bovis B,Mugnier B,Chollat-Namy A,Malissen B,Méresse S,Gorvel JP
56-5321 was used in Flow cytometry/Cell sorting to investigate the expression of lysozyme in the Peyer's patches, showing that pathogenic bacteria and dead cells are internalised by a unique subset of dendritic cells expressing lysozyme.
Fri Jan 01 00:00:00 EST 2010
IL-37 is a fundamental inhibitor of innate immunity.
Nature immunology
Nold MF,Nold-Petry CA,Zepp JA,Palmer BE,Bufler P,Dinarello CA
56-5321 was used in Flow cytometry/Cell sorting to determine the function of interleukin 37.
Mon Nov 01 00:00:00 EDT 2010
Diabetic mice display a delayed adaptive immune response to Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950)
Vallerskog T,Martens GW,Kornfeld H
56-5321 was used in Flow cytometry/Cell sorting to conclude that TB increased susceptibility in DM results from a delayed innate immune response to the presence of M. tuberculosis-infected alveolar macrophages.
Tue Jun 01 00:00:00 EDT 2010
Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses.
Journal of immunology (Baltimore, Md. : 1950)
Larson RP,Zimmerli SC,Comeau MR,Itano A,Omori M,Iseki M,Hauser C,Ziegler SF
56-5321 was used in Flow cytometry/Cell sorting to demonstrate a role for TSLP in a Th2 model of contact hypersensitivity in mice.
Mon Mar 15 00:00:00 EDT 2010
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tait ED,Jordan KA,Dupont CD,Harris TH,Gregg B,Wilson EH,Pepper M,Dzierszinski F,Roos DS,Hunter CA
56-5321 was used in Flow cytometry/Cell sorting to show the dendritic cell response to T.gondii alters levels of CD8+ T cells which ultimately determine the outcome of infection.
Sun Aug 01 00:00:00 EDT 2010
Vector transmission of leishmania abrogates vaccine-induced protective immunity.
PLoS pathogens
Peters NC,Kimblin N,Secundino N,Kamhawi S,Lawyer P,Sacks DL
56-5321 was used in Flow cytometry/Cell sorting to identify the critical immunological factors influencing vaccine efficacy following natural transmissions of Leishmania.
Mon Jun 01 00:00:00 EDT 2009
Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection.
Cellular immunology
Pecora ND,Fulton SA,Reba SM,Drage MG,Simmons DP,Urankar-Nagy NJ,Boom WH,Harding CV
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Flow Cytometry
Fri Jan 02 00:00:00 EST 2009
Infiltration of inflammatory cells plays an important role in matrix metalloproteinase expression and activation in the heart during sepsis.
The American journal of pathology
Cuenca J,Martín-Sanz P,Alvarez-Barrientos AM,Boscá L,Goren N
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 56-5321-82) in Immunohistochemistry
Wed Nov 01 00:00:00 EST 2006
