Product References
Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.
Cellular & molecular biology letters
Meng Y,Pospiech M,Ali A,Chandwani R,Vergel M,Onyemaechi S,Yaghmour G,Lu R,Alachkar H
50-0341-82 was used in Flow cytometry/Cell sorting to investigate whether targeting CD36 has any detrimental impact on normal hematopoietic cells.
Wed May 24 00:00:00 EDT 2023
A Myb enhancer-guided analysis of basophil and mast cell differentiation.
Nature communications
Matsumura T,Totani H,Gunji Y,Fukuda M,Yokomori R,Deng J,Rethnam M,Yang C,Tan TK,Karasawa T,Kario K,Takahashi M,Osato M,Sanda T,Suda T
50-0341-82 was used in Flow Cytometry to identify the Myb -68 enhancer, a regulatory element which marks basophils and mast cells, and show a population of granulocyte-macrophage progenitors with higher potential to differentiate into basophils and mast cells.
Fri Nov 18 00:00:00 EST 2022
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging.
Nature communications
Palla AR,Hilgendorf KI,Yang AV,Kerr JP,Hinken AC,Demeter J,Kraft P,Mooney NA,Yucel N,Burns DM,Wang YX,Jackson PK,Blau HM
50-0341-82 was used in Flow Cytometry to provide fresh insights into the signaling dysfunction in aged MuSCs and identify the ciliary Hedgehog signaling pathway as a potential therapeutic target to counter the loss of muscle regenerative capacity which accompanies aging.
Thu Mar 17 00:00:00 EDT 2022
Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution.
Scientific reports
Rossi G,Giger S,Hübscher T,Lutolf MP
50-0341-82 was used in Flow cytometry/Cell sorting to capture features of embryonic blood development through a combination of immunophenotyping, detailed transcriptomics analysis, and identification of blood stem/progenitor cell potency.
Thu Aug 04 00:00:00 EDT 2022
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
50-0341-82 was used in Flow Cytometry to determine response to chemical signalling caused by endogenous retrovirus in skin microbiota.
Thu Jul 08 00:00:00 EDT 2021
HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.
Cell stem cell
Lv K,Gong C,Antony C,Han X,Ren JG,Donaghy R,Cheng Y,Pellegrino S,Warren AJ,Paralkar VR,Tong W
50-0341-82 was used in Flow cytometry/Cell sorting to reveal a role of the E3 ubiquitin ligase HectD1 in regulating HSC function via ribosome assembly and protein translation.
Thu Jul 01 00:00:00 EDT 2021
Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation.
Cell stem cell
Cordero-Espinoza L,Dowbaj AM,Kohler TN,Strauss B,Sarlidou O,Belenguer G,Pacini C,Martins NP,Dobie R,Wilson-Kanamori JR,Butler R,Prior N,Serup P,Jug F,Henderson NC,Hollfelder F,Huch M
50-0341-82 was used in Flow cytometry/Cell sorting to expand the concept of the cellular niche in epithelial tissues, whereby not only soluble factors but also cell-cell contacts are the key regulatory cues involved in the control of cellular behaviors, suggesting a critical role for cell-cell contacts during regeneration.
Thu Nov 04 00:00:00 EDT 2021
In Lyl1-/- mice, adipose stem cell vascular niche impairment leads to premature development of fat tissues.
Stem cells (Dayton, Ohio)
Hussain A,Deleuze V,El Kebriti L,Turali H,Pirot N,Glasson Y,Mathieu D,Pinet V
50-0341 was used in Flow cytometry/Cell sorting to highlight the major structural role of the adipose tissue vascular niche in coordinating stem cell self-renewal and differentiation into adipocytes.
Fri Jan 01 00:00:00 EST 2021
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell reports
Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R
50-0341-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.
Tue Jul 13 00:00:00 EDT 2021
Hydrogels Containing Gradients in Vascular Density Reveal Dose-Dependent Role of Angiocrine Cues on Stem Cell Behavior.
Advanced functional materials
Ngo MT,Barnhouse VR,Gilchrist AE,Mahadik BP,Hunter CJ,Hensold JN,Petrikas N,Harley BAC
50-0341-82 was used in Flow cytometry/Cell sorting to report the successful development of a microfluidic device to generate hydrogels containing lateral gradients in vascular density as a means to identify angiocrine signals underlying hematopoietic stem cell culture ex vivo.
Thu Dec 16 00:00:00 EST 2021
Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells.
Cell
Shwartz Y,Gonzalez-Celeiro M,Chen CL,Pasolli HA,Sheu SH,Fan SM,Shamsi F,Assaad S,Lin ET,Zhang B,Tsai PC,He M,Tseng YH,Lin SJ,Hsu YC
50-0341-82 was used in Flow Cytometry to demonstrate sympathetic nerves can modulate stem cells through synapse-like connections and neurotransmitters to couple tissue production with demands.
Thu Aug 06 00:00:00 EDT 2020
Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.
Cell metabolism
Kim CS,Ding X,Allmeroth K,Biggs LC,Kolenc OI,L'Hoest N,Chacón-Martínez CA,Edlich-Muth C,Giavalisco P,Quinn KP,Denzel MS,Eming SA,Wickström SA
50-0341-82 was used in Flow Cytometry to highlight the importance of spatiotemporal control of SC metabolic states in organ homeostasis.
Tue Oct 06 00:00:00 EDT 2020
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Cell stem cell
Shen C,Sheng Y,Zhu AC,Robinson S,Jiang X,Dong L,Chen H,Su R,Yin Z,Li W,Deng X,Chen Y,Hu YC,Weng H,Huang H,Prince E,Cogle CR,Sun M,Zhang B,Chen CW,Marcucci G,He C,Qian Z,Chen J
50-0341-82 was used in Flow Cytometry to reveal crucial functions of ALKBH5 in leukemogenesis and LSC/LIC self-renewal/maintenance and highlight the therapeutic potential of targeting the ALKBH5/m6A axis.
Thu Jul 02 00:00:00 EDT 2020
The aging skin microenvironment dictates stem cell behavior.
Proceedings of the National Academy of Sciences of the United States of America
Ge Y,Miao Y,Gur-Cohen S,Gomez N,Yang H,Nikolova M,Polak L,Hu Y,Verma A,Elemento O,Krueger JG,Fuchs E
50-0341 was used in Flow cytometry/Cell sorting to highlight the importance of SC:niche interactions and favor a model where youthfulness of the niche microenvironment plays a dominant role in dictating the properties of its SCs and tissue health and fitness.
Tue Mar 10 00:00:00 EDT 2020
Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform.
The Analyst
Pastrana-Otero I,Majumdar S,Gilchrist AE,Gorman BL,Harley BAC,Kraft ML
50-0341-82 was used in Flow Cytometry to show that the spectra acquired from individual living cells on functionalized PA gels attached to our custom substrates were of sufficient quality to enable accurate identification of cell phenotypes using PLS-DA models of the cell spectra.
Mon Oct 26 00:00:00 EDT 2020
Explant culture: A relevant tool for the study of telocytes.
Cell biology international
Sanches BDA,Maldarine JDS,Tamarindo GH,Da Silva ADT,Lima MLD,Rahal P,Góes RM,Taboga SR,Carvalho HF
50-0341-82 was used in Immunocytochemistry to elucidate the nature of telocytes and their functions.
Tue Dec 01 00:00:00 EST 2020
An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration.
Molecular biology of the cell
Su S,Begum S,Ezratty EJ
50-0341 was used in Flow cytometry/Cell sorting to examine the role of intraflagellar transport (IFT) 20 (Ift20) during polarized migration of epidermal cells.
Sat Aug 01 00:00:00 EDT 2020
miR‑210 enhances mesenchymal stem cell‑modulated neural precursor cell migration.
Molecular medicine reports
Wang F,Zhu J,Zheng J,Duan W,Zhou Z
50-0341 was used in Flow cytometry/Cell sorting to study the effects of bone marrow-derived mesenchymal stem cells (BMSCs) on neural precursor cell (NPC) migration.
Mon Jun 01 00:00:00 EDT 2020
Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche.
Integrative biology : quantitative biosciences from nano to macro
Gilchrist AE,Harley BAC
50-0341-82 was used in Flow Cytometry to investigate the mechanism of how marrow-derived mesenchymal stromal and progenitor cells impacts hematopoietic stem cells fate decisions.
Fri Jul 10 00:00:00 EDT 2020
Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice.
Molecular brain
Tribble JR,Harder JM,Williams PA,John SWM
50-0341 was used in Flow cytometry/Cell sorting to demonstrate that prophylactic radiation therapy of DBA/2 J mice potently abolishes these microglia metabolic transcriptomic changes at the same time points.
Mon May 25 00:00:00 EDT 2020
Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS.
Journal of neuroinflammation
Hohsfield LA,Najafi AR,Ghorbanian Y,Soni N,Hingco EE,Kim SJ,Jue AD,Swarup V,Inlay MA,Green KN
50-0341 was used in Flow Cytometry to characterize the role and complexity of myeloid cells in the regulation of CNS cells and functional outcomes in the brain.
Sun Sep 20 00:00:00 EDT 2020
Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.
Cell reports
Hidalgo San Jose L,Sunshine MJ,Dillingham CH,Chua BA,Kruta M,Hong Y,Hatters DM,Signer RAJ
50-0341 was used in Flow cytometry/Cell sorting to show that hematopoietic stem cells (HSCs) are dependent on low protein synthesis to maintain proteostasis, which promotes their self-renewal.
Tue Jan 07 00:00:00 EST 2020
Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice.
Journal of lipid research
LeBlond ND,Ghorbani P,O'Dwyer C,Ambursley N,Nunes JRC,Smith TKT,Trzaskalski NA,Mulvihill EE,Viollet B,Foretz M,Fullerton MD
50-0341 was used in Flow cytometry/Cell sorting to clarify and female mice made acutely atherosclerotic by injection of AAV vector encoding a gain-of-function mutant PCSK9 (PCSK9-AAV) and WD feeding.
Tue Dec 01 00:00:00 EST 2020
Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding.
Cell stem cell
Pei W,Shang F,Wang X,Fanti AK,Greco A,Busch K,Klapproth K,Zhang Q,Quedenau C,Sauer S,Feyerabend TB,Höfer T,Rodewald HR
50-0341 was used in Flow cytometry/Cell sorting to develop the PolyloxExpress allele, enabling Cre-recombinase-dependent RNA barcoding in situ.
Thu Sep 03 00:00:00 EDT 2020
Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth.
Cell reports
Davidson S,Efremova M,Riedel A,Mahata B,Pramanik J,Huuhtanen J,Kar G,Vento-Tormo R,Hagai T,Chen X,Haniffa MA,Shields JD,Teichmann SA
50-0341-82 was used in Immunohistochemistry to identify complex interplays and increase stromal diversity as a tumor develops, revealing that stromal cells acquire the capacity to modulate immune landscapes from early disease.
Tue May 19 00:00:00 EDT 2020
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Cell stem cell
Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R
50-0341-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.
Thu May 02 00:00:00 EDT 2019
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.
The Journal of clinical investigation
Soukup AA,Zheng Y,Mehta C,Wu J,Liu P,Cao M,Hofmann I,Zhou Y,Zhang J,Johnson KD,Choi K,Keles S,Bresnick EH
50-0341 was used in Flow cytometry/Cell sorting to study the mechanisms underlying how GATA2 enhancer disease mutations impact hematopoiesis and pathology.
Fri Mar 01 00:00:00 EST 2019
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
The Journal of clinical investigation
Abraham A,Qiu S,Chacko BK,Li H,Paterson A,He J,Agarwal P,Shah M,Welner R,Darley-Usmar VM,Bhatia R
50-0341 was used in Flow cytometry/Cell sorting to demonstrate an important role for SIRT1 in leukemia development.
Mon Jun 10 00:00:00 EDT 2019
Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation.
Cancer research
Li H,Petersen S,Garcia Mariscal A,Brakebusch C
50-0341-82 was used in Flow Cytometry to study how mice with a keratinocyte-restricted deletion of the actin-polymerization promoting molecule N-WASP display cyclic hair loss and skin inflammation.
Wed May 01 00:00:00 EDT 2019
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.
Cell stem cell
Vannini N,Campos V,Girotra M,Trachsel V,Rojas-Sutterlin S,Tratwal J,Ragusa S,Stefanidis E,Ryu D,Rainer PY,Nikitin G,Giger S,Li TY,Semilietof A,Oggier A,Yersin Y,Tauzin L,Pirinen E,Cheng WC,Ratajczak J,Canto C,Ehrbar M,Sizzano F,Petrova TV,Vanhecke D,Zhang L,Romero P,Nahimana A,Cherix S,Duchosal MA,Ho PC,Deplancke B,Coukos G,Auwerx J,Lutolf MP,Naveiras O
50-0341-82 was used in Flow Cytometry to demonstrate a positive effect of NAD+-boosting strategies on the most primitive blood stem cells, establishing a link between HSC mitochondrial stress, mitophagy, and stem-cell fate decision.
Thu Mar 07 00:00:00 EST 2019
Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.
Nature medicine
Maryanovich M,Zahalka AH,Pierce H,Pinho S,Nakahara F,Asada N,Wei Q,Wang X,Ciero P,Xu J,Leftin A,Frenette PS
50-0341 was used in Flow cytometry/Cell sorting to determine whether haematopoietic stem cell ageing depends on bone marrow innervation by the sympathetic nervous system.
Fri Jun 01 00:00:00 EDT 2018
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.
Immunity
Emgård J,Kammoun H,García-Cassani B,Chesné J,Parigi SM,Jacob JM,Cheng HW,Evren E,Das S,Czarnewski P,Sleiers N,Melo-Gonzalez F,Kvedaraite E,Svensson M,Scandella E,Hepworth MR,Huber S,Ludewig B,Peduto L,Villablanca EJ,Veiga-Fernandes H,Pereira JP,Flavell RA,Willinger T
50-0341-82 was used in Immunohistochemistry to show that GPR183 promotes lymphoid organ development and indicate that oxysterol-GPR183-dependent positioning within tissues controls ILC3 activity and intestinal homeostasis.
Tue Jan 16 00:00:00 EST 2018
Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.
Cell stem cell
Duarte D,Hawkins ED,Akinduro O,Ang H,De Filippo K,Kong IY,Haltalli M,Ruivo N,Straszkowski L,Vervoort SJ,McLean C,Weber TS,Khorshed R,Pirillo C,Wei A,Ramasamy SK,Kusumbe AP,Duffy K,Adams RH,Purton LE,Carlin LM,Lo Celso C
50-0341 was used in Flow cytometry/Cell sorting to suggest that preventing degradation of the endosteal vasculature may improve current paradigms for treating acute myeloid leukemia.
Thu Jan 04 00:00:00 EST 2018
RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism.
Small GTPases
García-Mariscal A,Peyrollier K,Basse A,Pedersen E,Rühl R,van Hengel J,Brakebusch C
50-0341 was used in Flow cytometry/Cell sorting to reveal a link between RhoA and retinoid signaling and uncover a pathway by which RhoA regulates gene expression.
Mon Sep 03 00:00:00 EDT 2018
MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity.
JCI insight
Lee-Sherick AB,Jacobsen KM,Henry CJ,Huey MG,Parker RE,Page LS,Hill AA,Wang X,Frye SV,Earp HS,Jordan CT,DeRyckere D,Graham DK
50-0341 was used in Flow cytometry/Cell sorting to demonstrate both the direct therapeutic effects of MERTK inhibition on leukaemia cells and the induction of anti-leukaemia immunity via suppression of the coinhibitory PD-1 axis.
Fri Nov 02 00:00:00 EDT 2018
Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M.
Nature communications
Sampath SC,Sampath SC,Ho ATV,Corbel SY,Millstone JD,Lamb J,Walker J,Kinzel B,Schmedt C,Blau HM
50-0341 was used in Flow cytometry/Cell sorting to identify Oncostatin M as a secreted niche factor responsible for quiescence induction.
Wed Apr 18 00:00:00 EDT 2018
Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis.
Cell death & disease
Feng Y,Liao Y,Huang W,Lai X,Luo J,Du C,Lin J,Zhang Z,Qiu D,Liu Q,Shen H,Xiang AP,Zhang Q
50-0341 was used in Flow cytometry/Cell sorting to study the role of matrix Gla protein as a novel mediator of mesenchymal stromal cell-mediated immunomodulation in treating Crohn's disease.
Thu Jun 07 00:00:00 EDT 2018
Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration.
Cell stem cell
Yu Z,Jiang K,Xu Z,Huang H,Qian N,Lu Z,Chen D,Di R,Yuan T,Du Z,Xie W,Lu X,Li H,Chai R,Yang Y,Zhu B,Kunieda T,Wang F,Chen T
50-0341 was used in Flow cytometry/Cell sorting to show that expression of Hoxc genes is sufficient to reprogram mesenchymal DP cells and alter the regenerative potential of epithelial stem cells.
Thu Oct 04 00:00:00 EDT 2018
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Cell
Cimmino L,Dolgalev I,Wang Y,Yoshimi A,Martin GH,Wang J,Ng V,Xia B,Witkowski MT,Mitchell-Flack M,Grillo I,Bakogianni S,Ndiaye-Lobry D,Martín MT,Guillamot M,Banh RS,Xu M,Figueroa ME,Dickins RA,Abdel-Wahab O,Park CY,Tsirigos A,Neel BG,Aifantis I
50-0341 was used in Flow cytometry/Cell sorting to determine the role of TET2 deficiency in leukaemia stem cell maintenance.
Thu Sep 07 00:00:00 EDT 2017
Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.
Cell
Ge Y,Gomez NC,Adam RC,Nikolova M,Yang H,Verma A,Lu CP,Polak L,Yuan S,Elemento O,Fuchs E
50-0341 was used in Flow cytometry/Cell sorting to investigate the homeostatic mechanisms of tissue regeneration and wound repair by tissue stem cells in the skin, that can be hijacked by cancer cells.
Thu May 04 00:00:00 EDT 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
50-0341 was used in Flow cytometry/Cell sorting to examine the significance of ubiquitin signalling in coordinating RNA processing by Toll-like receptor pathways during an immune response and in premalignant haematologic diseases.
Wed Feb 01 00:00:00 EST 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
50-0341 was used in Flow cytometry/Cell sorting to demonstrate that the effects of cytokines regulating haematopoietic stem cell functions are dependent on the producing cell sources.
Wed Mar 01 00:00:00 EST 2017
AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis.
Circulation research
Abdel Malik R,Zippel N,Frömel T,Heidler J,Zukunft S,Walzog B,Ansari N,Pampaloni F,Wingert S,Rieger MA,Wittig I,Fisslthaler B,Fleming I
50-0341 was used in Flow cytometry/Cell sorting to elucidate the role of the AMPKa2 catalytic subunit in vascular repair following ischemia.
Fri Jan 06 00:00:00 EST 2017
Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny.
The EMBO journal
Chacón-Martínez CA,Klose M,Niemann C,Glauche I,Wickström SA
50-0341 was used in Flow cytometry/Cell sorting to uncovers regulatory dynamics by which phenotypic plasticity of cells drives population-level homeostasis within a niche, and provides a discovery tool for studies on adult stem cell fate.
Tue Jan 17 00:00:00 EST 2017
CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury.
Proceedings of the National Academy of Sciences of the United States of America
Stzepourginski I,Nigro G,Jacob JM,Dulauroy S,Sansonetti PJ,Eberl G,Peduto L
50034182 was used in flow cytometry to discuss the relationship between CD34+ Gp38+ mesenchymal cells and Lgr5+ intestinal epithelial stem cells
Tue Jan 24 00:00:00 EST 2017
Notch4 signaling pathway in a Kawasaki disease mouse model induced by Lactobacillus casei cell wall extract.
Experimental and therapeutic medicine
Gao L,Fu S,Wang W,Xie C,Zhang Y,Gong F
50-0341 was used in Flow cytometry/Cell sorting to show the Notch4 signalling pathway participates in coronary artery lesions in Kawasaki disease animal models induced by Lactobacillus casei cell wall extract.
Thu Jun 01 00:00:00 EDT 2017
Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment.
Nature communications
Wong JJ,Gao D,Nguyen TV,Kwok CT,van Geldermalsen M,Middleton R,Pinello N,Thoeng A,Nagarajah R,Holst J,Ritchie W,Rasko JEJ
50-0341 was used in Flow cytometry/Cell sorting to determine whether intron retention is regulated by spliceosomal and DNA methylation changes and how they are linked.
Mon May 08 00:00:00 EDT 2017
Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment.
Nature communications
Wong JJ,Gao D,Nguyen TV,Kwok CT,van Geldermalsen M,Middleton R,Pinello N,Thoeng A,Nagarajah R,Holst J,Ritchie W,Rasko JEJ
50-0341 was used in Flow cytometry/Cell sorting to determine whether intron retention is regulated by spliceosomal and DNA methylation changes and how they are linked.
Mon May 08 00:00:00 EDT 2017
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.
Cell
Yu VWC,Yusuf RZ,Oki T,Wu J,Saez B,Wang X,Cook C,Baryawno N,Ziller MJ,Lee E,Gu H,Meissner A,Lin CP,Kharchenko PV,Scadden DT
50034182 was used in flow cytometry to study epigenetic heterogeneity in hematopoietic stem cells.
Thu Nov 17 00:00:00 EST 2016
Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin.
Cell
Keyes BE,Liu S,Asare A,Naik S,Levorse J,Polak L,Lu CP,Nikolova M,Pasolli HA,Fuchs E
50-0341 was used in Flow cytometry/Cell sorting to define age-related defects that underlie impaired re-epithelialisation after skin wounding in mice.
Thu Nov 17 00:00:00 EST 2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Nature cell biology
Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E
50-0341 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.
Wed Jun 01 00:00:00 EDT 2016
Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21(∗) in SCC progression.
Nature cell biology
Ge Y,Zhang L,Nikolova M,Reva B,Fuchs E
50-0341 was used in Flow cytometry/Cell sorting to identify which of the microRNAs abundantly expressed in squamous cell carcinoma are key drivers in malignant progression.
Fri Jan 01 00:00:00 EST 2016
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
50-0341 was used in Flow cytometry/Cell sorting to study how CD19 CAR immune pressure induces a B-precursor acute lymphoblastic leukaemia lineage switch.
Wed Jul 27 00:00:00 EDT 2016
Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis.
PloS one
Arcipowski KM,Bulic M,Gurbuxani S,Licht JD
50-0341 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which MLL3 loss contributes to myeloid malignancies, showing that it promotes aberrant myelopoiesis.
Mon Aug 28 00:00:00 EDT 2017
Isolation and Fluorescence-Activated Cell Sorting of Mouse Keratinocytes Expressing β-Galactosidase.
Methods in molecular biology (Clifton, N.J.)
Kasper M,Toftgård R,Jaks V
50-0341-82 was used in flow cytometry to provide a guideline for the isolation of viable murine epidermal cells expressing β-gal which can then be subjected to further characterization flow cytometry or flow cytometry.
Fri Jan 12 00:00:00 EST 2018
Tumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapy.
Science translational medicine
Moding EJ,Castle KD,Perez BA,Oh P,Min HD,Norris H,Ma Y,Cardona DM,Lee CL,Kirsch DG
50-0341 was used in Flow cytometry/Cell sorting to investigate the contribution of different cell types to tumour response to radiation.
Wed Mar 11 00:00:00 EDT 2015
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis.
Cell reports
Morgado-Palacin L,Varetti G,Llanos S,Gómez-López G,Martinez D,Serrano M
50-0341 was used in Flow cytometry/Cell sorting to conclude that Rpl11-deficient mice recapitulate DBA disorder, including cancer predisposition.
Tue Oct 27 00:00:00 EDT 2015
Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle.
eLife
Xu Z,Wang W,Jiang K,Yu Z,Huang H,Wang F,Zhou B,Chen T
50-0341 was used in Flow cytometry/Cell sorting to demonstrate that long-term hair follicle stem cells arise from embryonic progenitor cells, a process mediated by attenuated Wnt/β-catenin signaling.
Mon Dec 14 00:00:00 EST 2015
STAT3 signaling controls satellite cell expansion and skeletal muscle repair.
Nature medicine
Tierney MT,Aydogdu T,Sala D,Malecova B,Gatto S,Puri PL,Latella L,Sacco A
50-0341 was used in Flow cytometry/Cell sorting to indicate that pharmacological manipulation of STAT3 activity can be used to counteract the functional exhaustion of satellite cells in pathological conditions.
Wed Oct 01 00:00:00 EDT 2014
In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators.
Nature cell biology
Lien WH,Polak L,Lin M,Lay K,Zheng D,Fuchs E
50-0341 was used in Flow cytometry/Cell sorting to show that during hair follicle stem cell quiescence, TCF3, TCF4 and TLE bind coordinately and repress Wnt target genes.
Sat Feb 01 00:00:00 EST 2014
Wt1-expressing progenitors contribute to multiple tissues in the developing lung.
American journal of physiology. Lung cellular and molecular physiology
Cano E,Carmona R,Muñoz-Chápuli R
50-0341 was used in Flow cytometry/Cell sorting to report a novel role for embryonic mesothelium-derived cells in lung morphogenesis.
Thu Aug 15 00:00:00 EDT 2013
Cells derived from the coelomic epithelium contribute to multiple gastrointestinal tissues in mouse embryos.
PloS one
Carmona R,Cano E,Mattiotti A,Gaztambide J,Muñoz-Chápuli R
50-0341 was used in Immunofluorescence on frozen tissues to investigate the contribution of coelomic epithelium-derived cells to the intestinal development, showing that they contribute to multiple gastrointestinal tissues in mouse embryos.
Fri Aug 09 00:00:00 EDT 2013
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.
Stem cells (Dayton, Ohio)
Singh P,Yao Y,Weliver A,Broxmeyer HE,Hong SC,Chang CH
Tue Apr 01 00:00:00 EDT 2008
The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.
The Journal of biological chemistry
Palazuelos J,Davoust N,Julien B,Hatterer E,Aguado T,Mechoulam R,Benito C,Romero J,Silva A,Guzmán M,Nataf S,Galve-Roperh I
Fri May 09 00:00:00 EDT 2008
Hair cycle-dependent changes of alkaline phosphatase activity in the mesenchyme and epithelium in mouse vibrissal follicles.
Development, growth & differentiation
Iida M,Ihara S,Matsuzaki T
Sun Apr 01 00:00:00 EDT 2007
Adult mouse hematopoietic stem cells: purification and single-cell assays.
Nature protocols
Ema H,Morita Y,Yamazaki S,Matsubara A,Seita J,Tadokoro Y,Kondo H,Takano H,Nakauchi H
Mon Nov 05 00:00:00 EST 2007
