Product References
Characterization of T Follicular Helper Cells and T Follicular Regulatory Cells in HIV-Infected and Sero-Negative Individuals.
Cells
Salvatore B,Resop RS,Gordon BR,Epeldegui M,Martinez-Maza O,Comin-Anduix B,Lam A,Wu TT,Uittenbogaart CH
45-0458-42 was used in Flow cytometry/Cell sorting to identify cytokines in peripheral blood T follicular helper cells and T follicular regulatory cells.
Thu Jan 12 00:00:00 EST 2023
Abnormally high expression of D1-like dopamine receptors on lupus CD4+ T cells promotes Tfh cell differentiation.
Lupus science & medicine
Wu F,Xiang Z,He Z,Yi P,Yang M,Wu H,Hu M
45-0458-42 was used in Flow cytometry/Cell sorting to explore the relationship between DRDs and Tfh cells, and analyse the relationship between DRD expression on Tfh cells and the course of SLE.
Tue Aug 01 00:00:00 EDT 2023
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
The Journal of experimental medicine
Louka E,Povinelli B,Rodriguez-Meira A,Buck G,Wen WX,Wang G,Sousos N,Ashley N,Hamblin A,Booth CAG,Roy A,Elliott N,Iskander D,de la Fuente J,Fordham N,O'Byrne S,Inglott S,Norfo R,Salio M,Thongjuea S,Rao A,Roberts I,Mead AJ
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Differences in Maturation Status and Immune Phenotypes of Circulating Helios+ and Helios- Tregs and Their Disrupted Correlations With Monocyte Subsets in Autoantibody-Positive T1D Individuals.
Frontiers in immunology
Zhang Y,Zhang J,Shi Y,Shen M,Lv H,Chen S,Feng Y,Chen H,Xu X,Yang T,Xu K
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Wed Sep 15 00:00:00 EDT 2021
Pre-existing immunity and vaccine history determine hemagglutinin-specific CD4 T cell and IgG response following seasonal influenza vaccination.
Nature communications
Wild K,Smits M,Killmer S,Strohmeier S,Neumann-Haefelin C,Bengsch B,Krammer F,Schwemmle M,Hofmann M,Thimme R,Zoldan K,Boettler T
45-0458-42 was used in Flow cytometry/Cell sorting to conclude that both pre-existing immunity and vaccine history contribute to the response to seasonal influenza vaccines.
Thu Nov 18 00:00:00 EST 2021
Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets.
Molecular cell
Psaila B,Wang G,Rodriguez-Meira A,Li R,Heuston EF,Murphy L,Yee D,Hitchcock IS,Sousos N,O'Sullivan J,Anderson S,Senis YA,Weinberg OK,Calicchio ML,Iskander D,Royston D,Milojkovic D,Roberts I,Bodine DM,Thongjuea S,Mead AJ
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Thu May 07 00:00:00 EDT 2020
The downregulated membrane expression of CD18 in CD34+ cells defines a primitive population of human hematopoietic stem cells.
Stem cell research & therapy
Mesa-Núñez C,Leon-Rico D,Aldea M,Damián C,Sanchez-Baltasar R,Sanchez R,Alberquilla O,Segovia JC,Bueren JA,Almarza E
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro.
Scientific reports
Papagno L,Kuse N,Lissina A,Gostick E,Price DA,Appay V,Nicoli F
45-0458-42 was used in Flow Cytometry to show that TLR9L is unlikely to be a good candidate for the optimal induction of de novo CD8+ T-cell responses, in contrast to adjuvants that operate via discrete PRRs.
Wed Jul 15 00:00:00 EDT 2020
Health-Related Quality of Life Among Homeless Smokers: Risk and Protective Factors of Latent Class Membership.
Behavioral medicine (Washington, D.C.)
Garey L,Reitzel LR,Neisler J,Kendzor DE,Zvolensky MJ,Neighbors C,Hernandez DC,Businelle MS
45-0458 was used in Flow cytometry/Cell sorting to characterize common classes of HRQoL among adult, homeless smokers, a particularly vulnerable group of the larger population, and to evaluate risk and protective factors of HRQoL class membership.
Tue Aug 06 00:00:00 EDT 2019
MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.
Molecular medicine reports
Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.
Nature communications
Bell CC,Fennell KA,Chan YC,Rambow F,Yeung MM,Vassiliadis D,Lara L,Yeh P,Martelotto LG,Rogiers A,Kremer BE,Barbash O,Mohammad HP,Johanson TM,Burr ML,Dhar A,Karpinich N,Tian L,Tyler DS,MacPherson L,Shi J,Pinnawala N,Yew Fong C,Papenfuss AT,Grimmond SM,Dawson SJ,Allan RS,Kruger RG,Vakoc CR,Goode DL,Naik SH,Gilan O,Lam EYN,Marine JC,Prinjha RK,Dawson MA
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Thu Jun 20 00:00:00 EDT 2019
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.
Nature immunology
Kong XF,Martinez-Barricarte R,Kennedy J,Mele F,Lazarov T,Deenick EK,Ma CS,Breton G,Lucero KB,Langlais D,Bousfiha A,Aytekin C,Markle J,Trouillet C,Jabot-Hanin F,Arlehamn CSL,Rao G,Picard C,Lasseau T,Latorre D,Hambleton S,Deswarte C,Itan Y,Abarca K,Moraes-Vasconcelos D,Ailal F,Ikinciogullari A,Dogu F,Benhsaien I,Sette A,Abel L,Boisson-Dupuis S,Schröder B,Nussenzweig MC,Liu K,Geissmann F,Tangye SG,Gros P,Sallusto F,Bustamante J,Casanova JL
45-0458-42 was used in Flow Cytometry to suggest that inherited SPPL2a deficiency in humans underlies mycobacterial disease by decreasing the numbers of cDC2s and impairing IFN-γ production by mycobacterium-specific memory TH1* cells.
Sat Sep 01 00:00:00 EDT 2018
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.
Nature
Eyquem J,Mansilla-Soto J,Giavridis T,van der Stegen SJ,Hamieh M,Cunanan KM,Odak A,Gönen M,Sadelain M
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Thu Mar 02 00:00:00 EST 2017
Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.
Blood
Hou TZ,Verma N,Wanders J,Kennedy A,Soskic B,Janman D,Halliday N,Rowshanravan B,Worth A,Qasim W,Baxendale H,Stauss H,Seneviratne S,Neth O,Olbrich P,Hambleton S,Arkwright PD,Burns SO,Walker LS,Sansom DM
45-0458 was used in Flow cytometry/Cell sorting to develop assays capable of distinguishing a variety of defects in the CTLA-4 pathway.
Thu Mar 16 00:00:00 EDT 2017
The distribution and function of human memory T cell subsets in lung cancer.
Immunologic research
Sheng SY,Gu Y,Lu CG,Zou JY,Hong H,Wang R
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia.
Oncoimmunology
Catakovic K,Gassner FJ,Ratswohl C,Zaborsky N,Rebhandl S,Schubert M,Steiner M,Gutjahr JC,Pleyer L,Egle A,Hartmann TN,Greil R,Geisberger R
Published figure using CD45RA monoclonal antibody (Product # 45-0458-42) in Flow Cytometry
Sat Jan 29 00:00:00 EST 2022
A distinct plasmablast and naïve B-cell phenotype in primary immune thrombocytopenia.
Haematologica
Flint SM,Gibson A,Lucas G,Nandigam R,Taylor L,Provan D,Newland AC,Savage CO,Henderson RB
45-0458 was used in Flow cytometry/Cell sorting to characterise the B- and T- cell compartments in patients with primary immune thrombocytopenia.
Wed Jun 01 00:00:00 EDT 2016
Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.
PLoS neglected tropical diseases
Katawa G,Layland LE,Debrah AY,von Horn C,Batsa L,Kwarteng A,Arriens S,W Taylor D,Specht S,Hoerauf A,Adjobimey T
45-0458 was used in Flow cytometry/Cell sorting to provide initial evidence that elevated frequencies of Th17 and Th2 cells form part of the immune network instigating the development of severe onchocerciasis.
Thu Jan 01 00:00:00 EST 2015
Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis.
PLoS pathogens
Le Saout C,Hasley RB,Imamichi H,Tcheung L,Hu Z,Luckey MA,Park JH,Durum SK,Smith M,Rupert AW,Sneller MC,Lane HC,Catalfamo M
45-0458 was used in Flow cytometry/Cell sorting to define the mechanisms behind immune cell maintenance in HIV infected individuals.
Sat Mar 01 00:00:00 EST 2014
Delta-like 1-mediated Notch signaling enhances the in vitro conversion of human memory CD4 T cells into FOXP3-expressing regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Mota C,Nunes-Silva V,Pires AR,Matoso P,Victorino RM,Sousa AE,Caramalho I
45-0458 was used in Flow cytometry/Cell sorting to investigate novel strategies to generate in vitro-induced Tregs.
Mon Dec 15 00:00:00 EST 2014
Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.
The Journal of allergy and clinical immunology
Ives ML,Ma CS,Palendira U,Chan A,Bustamante J,Boisson-Dupuis S,Arkwright PD,Engelhard D,Averbuch D,Magdorf K,Roesler J,Peake J,Wong M,Adelstein S,Choo S,Smart JM,French MA,Fulcher DA,Cook MC,Picard C,Durandy A,Tsumura M,Kobayashi M,Uzel G,Casanova JL,Tangye SG,Deenick EK
45-0458 was used in Flow cytometry/Cell sorting to investigate the role of IL-21 and associated pathways in CD8(+) T-cell immunity in humans, showing that STAT3 mutations impair CD8(+) T-cell memory formation and function.
Thu Aug 01 00:00:00 EDT 2013
Long-term immune reconstitution of naive and memory t cell pools after haploidentical hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Azevedo RI,Soares MV,Albuquerque AS,Tendeiro R,Soares RS,Martins M,Ligeiro D,Victorino RM,Lacerda JF,Sousa AE
45-0458 was used in Flow cytometry/Cell sorting to show that long-term immune reconstitution was successfully achieved after haploidentical hematopoietic stem cell transplantation, a process that appears to have largely relied on de novo T cell production.
Wed May 01 00:00:00 EDT 2013
DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice.
The Journal of experimental medicine
Randall KL,Chan SS,Ma CS,Fung I,Mei Y,Yabas M,Tan A,Arkwright PD,Al Suwairi W,Lugo Reyes SO,Yamazaki-Nakashimada MA,Garcia-Cruz Mde L,Smart JM,Picard C,Okada S,Jouanguy E,Casanova JL,Lambe T,Cornall RJ,Russell S,Oliaro J,Tangye SG,Bertram EM,Goodnow CC
45-0458 was used in Flow cytometry/Cell sorting to study the role of DOCK8 in the survival and function of human and mouse CD8 T cells.
Mon Oct 24 00:00:00 EDT 2011