Product References
Direct and Indirect Effects of Filamin A on Tau Pathology in Neuronal Cells.
Molecular neurobiology
Levert S,Pilliod J,Aumont É,Armanville S,Tremblay C,Calon F,Leclerc N
44-768G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that in Tauopathies, FLNA could contribute to Tau pathology by acting on Tau and annexin A2.
Wed Feb 01 00:00:00 EST 2023
Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice.
Neural regeneration research
Yan F,Liu J,Chen MX,Zhang Y,Wei SJ,Jin H,Nie J,Fu XL,Shi JS,Zhou SY,Jin F
44-768G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that icariin can improve learning and memory impairments in the mouse model of Alzheimer's disease by regulating brain insulin signaling and glucose transporters.
Sun Jan 01 00:00:00 EST 2023
RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.
Acta neuropathologica
Kim YA,Siddiqui T,Blaze J,Cosacak MI,Winters T,Kumar A,Tein E,Sproul AA,Teich AF,Bartolini F,Akbarian S,Kizil C,Hargus G,Santa-Maria I
44-768G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that neuronal NSun2 deficiency promotes dysregulation of miR-125b and tau phosphorylation in AD and highlights a novel avenue for therapeutic targeting.
Sun Jan 01 00:00:00 EST 2023
Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy.
Molecular neurodegeneration
Brody AH,Nies SH,Guan F,Smith LM,Mukherjee B,Salazar SA,Lee S,Lam TKT,Strittmatter SM
Published figure using Phospho-Tau (Ser199, Ser202) polyclonal antibody (Product # 44-768G) in Western Blot
Tue May 03 00:00:00 EDT 2022
High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner.
Journal of neuroinflammation
Gannon OJ,Robison LS,Salinero AE,Abi-Ghanem C,Mansour FM,Kelly RD,Tyagi A,Brawley RR,Ogg JD,Zuloaga KL
44-768G was used in Western Blotting to indicate that High-fat diet had a wider array of metabolic, cognitive, and neuropathological consequences in AD and MxD females compared to males.
Sat May 14 00:00:00 EDT 2022
Tau protein is differentially phosphorylated in young- and old-aged rats with experimentally induced hyperthyroidism.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Tan B,Babur E,Toy N,Günaydın B,Dursun N,Süer C
44-768G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to study long-term potentiation (LTP) and accompanying phosphorylation of Tau protein in different residues in the hippocampus of young and old rats with experimentally induced hyperthyroidism.
Tue Nov 01 00:00:00 EDT 2022
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease.
Acta pharmacologica Sinica
Wang XJ,Qi L,Cheng YF,Ji XF,Chi TY,Liu P,Zou LB
44-768G was used in Western Blotting to support a critical role of PINK1-mediated mitophagy in controlling mitochondrial quality, tau hyperphosphorylation, and oxidative stress in a rat model of Alzheimer's disease.
Mon Aug 01 00:00:00 EDT 2022
PKR kinase directly regulates tau expression and Alzheimer's disease-related tau phosphorylation.
Brain pathology (Zurich, Switzerland)
Reimer L,Betzer C,Kofoed RH,Volbracht C,Fog K,Kurhade C,Nilsson E,Överby AK,Jensen PH
44-768G was used in Western Blot to indicate that PKR, independent of other kinases and upon acute brain inflammation, is capable of triggering pathological modulation of tau, which, in turn, might form the initial pathologic seed in several tauopathies such as Alzheimer's disease and Chronic traumatic encephalopathy where inflammation is severe.
Fri Jan 01 00:00:00 EST 2021
Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease.
Biochimica et biophysica acta. Molecular cell research
Alavi MV
Mon Nov 01 00:00:00 EDT 2021
A high fat, sugar, and salt Western diet induces motor-muscular and sensory dysfunctions and neurodegeneration in mice during aging: Ameliorative action of metformin.
CNS neuroscience & therapeutics
Hong S,Nagayach A,Lu Y,Peng H,Duong QA,Pham NB,Vuong CA,Bazan NG
44-768G was used in Immunohistochemistry to assess cerebral cortex abnormalities associated with sensory and motor dysfunctions and cellular and molecular insights in brains using HFSS-fed mice during aging.
Wed Dec 01 00:00:00 EST 2021
Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice.
The Journal of pathology
Wijesekara N,Gonçalves RA,Ahrens R,Ha K,De Felice FG,Fraser PE
44-768G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to validate that tau and IAPP amyloid act co-ordinately to impair beta cell function and glucose homeostasis, suggesting that combined pathological actions of these proteins may be a potential mechanism connecting AD and T2D.
Thu Jul 01 00:00:00 EDT 2021
Phosphorylated tau interactome in the human Alzheimer's disease brain.
Brain : a journal of neurology
Drummond E,Pires G,MacMurray C,Askenazi M,Nayak S,Bourdon M,Safar J,Ueberheide B,Wisniewski T
44-768G was used in Immunoprecipitation to determine the phosphorylated tau interactome.
Tue Sep 01 00:00:00 EDT 2020
Noncanonical function of an autophagy protein prevents spontaneous Alzheimer's disease.
Science advances
Heckmann BL,Teubner BJW,Boada-Romero E,Tummers B,Guy C,Fitzgerald P,Mayer U,Carding S,Zakharenko SS,Wileman T,Green DR
44-768G was used in Immunocytochemistry to find that loss of WD domain of the autophagy protein Atg16L drives spontaneous Alzheimer's disease in mice.
Sat Aug 01 00:00:00 EDT 2020
Noncanonical function of an autophagy protein prevents spontaneous Alzheimer's disease.
Science advances
Heckmann BL,Teubner BJW,Boada-Romero E,Tummers B,Guy C,Fitzgerald P,Mayer U,Carding S,Zakharenko SS,Wileman T,Green DR
44-768G was used in Immunocytochemistry to find that loss of WD domain of the autophagy protein Atg16L drives spontaneous Alzheimer's disease in mice.
Sat Aug 01 00:00:00 EDT 2020
Noncanonical function of an autophagy protein prevents spontaneous Alzheimer's disease.
Science advances
Heckmann BL,Teubner BJW,Boada-Romero E,Tummers B,Guy C,Fitzgerald P,Mayer U,Carding S,Zakharenko SS,Wileman T,Green DR
44-768G was used in Immunocytochemistry to find that loss of WD domain of the autophagy protein Atg16L drives spontaneous Alzheimer's disease in mice.
Sat Aug 01 00:00:00 EDT 2020
Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in.
Neurobiology of disease
Chiasseu M,Fesharaki-Zadeh A,Saito T,Saido TC,Strittmatter SM
44-768G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal that rmCHI enhances accumulation of amyloid-β and hyperphosphorylated tau inclusions, as well as neuroinflammation in AppNL-F/NL-F mice.
Sun Nov 01 00:00:00 EDT 2020
Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion.
The Journal of biological chemistry
Pilliod J,Desjardins A,Pernègre C,Jamann H,Larochelle C,Fon EA,Leclerc N
44-768G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Dot Blot to indicate that VAMP8 could be used to increase tau and α-synuclein clearance to prevent their intracellular accumulation.
Fri Dec 18 00:00:00 EST 2020
LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.
Cell
Heckmann BL,Teubner BJW,Tummers B,Boada-Romero E,Harris L,Yang M,Guy CS,Zakharenko SS,Green DR
44-768G was used in Immunohistochemistry-immunofluorescence to support a protective role for LANDO in microglia in neurodegenerative pathologies resulting from β-amyloid deposition.
Thu Jul 25 00:00:00 EDT 2019
DNA damage as a marker of brain damage in individuals with history of concussions.
Laboratory investigation; a journal of technical methods and pathology
Schwab N,Tator C,Hazrati LN
44-768G was used in Immunohistochemistry to investigate the DNA damage caused by mild traumatic brain injuries in two men with a history of concussions. Immunohistochemistry revealed extensive DNA damage throughout the frontal cortex, hippocampus, and brainstem areas.
Mon Jul 01 00:00:00 EDT 2019
A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer's disease brain.
Acta neuropathologica communications
Ercan-Herbst E,Ehrig J,Schöndorf DC,Behrendt A,Klaus B,Gomez Ramos B,Prat Oriol N,Weber C,Ehrnhoefer DE
Published figure using Phospho-Tau (Ser199, Ser202) polyclonal antibody (Product # 44-768G) in ELISA
Tue Dec 03 00:00:00 EST 2019
DNA repair deficiency and senescence in concussed professional athletes involved in contact sports.
Acta neuropathologica communications
Schwab N,Grenier K,Hazrati LN
44-768G was used in Immunohistochemistry to assess clinical presentation, neuropathological changes, load of DNA damage, morphological markers of cellular senescence, and expression of genes involved in DNA damage signaling, DNA repair, and cellular senescence including the senescence-associated secretory phenotype (SASP) in 38 professional athletes.
Thu Nov 14 00:00:00 EST 2019
Rab7A regulates tau secretion.
Journal of neurochemistry
Rodriguez L,Mohamed NV,Desjardins A,Lippé R,Fon EA,Leclerc N
Published figure using Phospho-Tau (Ser199, Ser202) polyclonal antibody (Product # 44-768G) in Western Blot
Mon May 01 00:00:00 EDT 2017
Liraglutide Improves Water Maze Learning and Memory Performance While Reduces Hyperphosphorylation of Tau and Neurofilaments in APP/PS1/Tau Triple Transgenic Mice.
Neurochemical research
Chen S,Sun J,Zhao G,Guo A,Chen Y,Fu R,Deng Y
44768G was used in western blot to elucidate how liraglutide affects disease and cognitive function in a mouse model of Alzheimer disease
Tue Aug 01 00:00:00 EDT 2017
Tau secretion is correlated to an increase of Golgi dynamics.
PloS one
Mohamed NV,Desjardins A,Leclerc N
Published figure using Phospho-Tau (Ser199, Ser202) polyclonal antibody (Product # 44-768G) in Western Blot
Mon Sep 18 00:00:00 EDT 2017
A validated antibody panel for the characterization of tau post-translational modifications.
Molecular neurodegeneration
Ercan E,Eid S,Weber C,Kowalski A,Bichmann M,Behrendt A,Matthes F,Krauss S,Reinhardt P,Fulle S,Ehrnhoefer DE
Published figure using Phospho-Tau (Ser199, Ser202) polyclonal antibody (Product # 44-768G) in Western Blot
Tue Nov 21 00:00:00 EST 2017
Chronic Traumatic Encephalopathy-Like Abnormalities in a Routine Neuropathology Service.
Journal of neuropathology and experimental neurology
Noy S,Krawitz S,Del Bigio MR
44768G was used in immunohistochemistry - paraffin section to evaluate chronic traumatic encephalopathy-like changes during routine neuropathology services
Thu Dec 01 00:00:00 EST 2016
Fyn inhibition rescues established memory and synapse loss in Alzheimer mice.
Annals of neurology
Kaufman AC,Salazar SV,Haas LT,Yang J,Kostylev MA,Jeng AT,Robinson SA,Gunther EC,van Dyck CH,Nygaard HB,Strittmatter SM
44-768G was used in western blot to assess the Src family kinase inhibitor, AZD0530, for treatment of Alzheimer's disease.
Mon Jun 01 00:00:00 EDT 2015
The choice of general anesthetics may not affect neuroinflammation and impairment of learning and memory after surgery in elderly rats.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Zhang J,Tan H,Jiang W,Zuo Z
44-768G was used in western blot to test if anesthetic choice affects cognitive impairment and neuroinflammation in elderly rat
Sun Mar 01 00:00:00 EST 2015
Human APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer model.
Human molecular genetics
Zhao W,Dumanis SB,Tamboli IY,Rodriguez GA,Jo Ladu M,Moussa CE,William Rebeck G
Sat Mar 01 00:00:00 EST 2014
Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice.
Neurobiology of aging
Ordóñez-Gutiérrez L,Torres JM,Gavín R,Antón M,Arroba-Espinosa AI,Espinosa JC,Vergara C,Del Río JA,Wandosell F
44-768G was used in western blot to test if β-amyloid accumulation affects prion infectivity and if different amounts of PrP affect β-amyloid accumulation.
Sun Dec 01 00:00:00 EST 2013
Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation.
Brain : a journal of neurology
Petratos S,Ozturk E,Azari MF,Kenny R,Lee JY,Magee KA,Harvey AR,McDonald C,Taghian K,Moussa L,Mun Aui P,Siatskas C,Litwak S,Fehlings MG,Strittmatter SM,Bernard CC
Fri Jun 01 00:00:00 EDT 2012
Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats.
Behavioural brain research
Lin D,Cao L,Wang Z,Li J,Washington JM,Zuo Z
44-768G was used in western blot to study the contribution of general anesthesia/anesthetics to post-operative cognitive dysfunction.
Sat Mar 17 00:00:00 EDT 2012
Transient focal cerebral ischemia/reperfusion induces early and chronic axonal changes in rats: its importance for the risk of Alzheimer's disease.
PloS one
Zhang Q,Gao T,Luo Y,Chen X,Gao G,Gao X,Zhou Y,Dai J
44-768G was used in Immunohistochemistry to suggest that transient cerebral ischemia/reperfusion induce early and chronic axonal changes.
Fri Aug 03 00:00:00 EDT 2012
Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction.
Journal of neuroscience research
Spatara ML,Robinson AS
44-768G was used in western blot to elucidate the between tau aggregation and the unfolded protein response in neurodegenerative disorders
Thu Jul 01 00:00:00 EDT 2010
Use of inhibitors in the study of MAP kinases.
Methods in molecular biology (Clifton, N.J.)
Burkhard K,Shapiro P
44-768G was used in western blot to discuss current methods to assess and inhibit MAP kinase signaling
Tue Dec 14 00:00:00 EST 2010
Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.
Endocrinology
Kim B,Backus C,Oh S,Hayes JM,Feldman EL
44-768G was used in immunohistochemistry and western blot to assess tau modification in type 1 and type 2 mouse models of diabetes
Tue Dec 01 00:00:00 EST 2009
A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons.
The EMBO journal
Zheng YL,Kesavapany S,Gravell M,Hamilton RS,Schubert M,Amin N,Albers W,Grant P,Pant HC
Wed Jan 12 00:00:00 EST 2005
