Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
25-0051-81 was used in Flow cytometry/Cell sorting to demonstrate that, in a dose-dependent manner CQ, suppresses the RANKL-induced osteoclastogenesis (p 0.001) as well as inhibiting the osteoclast functional activity (p 0.001) in mouse bone marrow cells (BMCs).
Wed Jan 04 00:00:00 EST 2023
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
25-0051-81 was used in Flow cytometry/Cell sorting to demonstrate that, in a dose-dependent manner CQ, suppresses the RANKL-induced osteoclastogenesis (p 0.001) as well as inhibiting the osteoclast functional activity (p 0.001) in mouse bone marrow cells (BMCs).
Wed Jan 04 00:00:00 EST 2023
IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection.
Nature communications
Xu L,Wei C,Chen Y,Wu Y,Shou X,Chen W,Lu D,Sun H,Li W,Yu B,Wang X,Zhang X,Yu Y,Lei Z,Tang R,Zhu J,Li Y,Lu L,Zhou H,Zhou S,Su C,Chen X
Published figure using CD5 monoclonal antibody (Product # 25-0051-81) in Flow Cytometry
Sat Nov 12 00:00:00 EST 2022
Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells (Bregs).
Frontiers in immunology
Sapra L,Shokeen N,Porwal K,Saini C,Bhardwaj A,Mathew M,Mishra PK,Chattopadhyay N,Dar HY,Verma B,Srivastava RK
25-0051-81 was used in Enzyme-linked immunosorbent assay to establish a novel osteo-protective and immunomodulatory potential of BL in augmenting bone health under osteoporotic conditions.
Tue Jun 14 00:00:00 EDT 2022
Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development.
Immunity
New JS,Dizon BLP,Fucile CF,Rosenberg AF,Kearney JF,King RG
25-0051-81 was used in Flow Cytometry to show that exposure to microbial antigens in early life determines the clonality of the mature B-1 B cell repertoire and ensuing antibody responses, with implications for vaccination approaches and schedules.
Tue Jul 14 00:00:00 EDT 2020
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
The Journal of clinical investigation
Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS
25-0051 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.
Wed Jul 01 00:00:00 EDT 2020
The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae.
Frontiers in immunology
Ercoli G,Ramos-Sevillano E,Nakajima R,de Assis RR,Jasinskas A,Goldblatt D,Felgner P,Weckbecker G,Brown J
Published figure using CD5 monoclonal antibody (Product # 25-0051-81) in Flow Cytometry
Tue Jun 22 00:00:00 EDT 2021
Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow.
Immunity
Walker JA,Clark PA,Crisp A,Barlow JL,Szeto A,Ferreira ACF,Rana BMJ,Jolin HE,Rodriguez-Rodriguez N,Sivasubramaniam M,Pannell R,Cruickshank J,Daly M,Haim-Vilmovsky L,Teichmann SA,McKenzie ANJ
25-0051 was used in Flow cytometry/Cell sorting to identify a discrete ILC2-committed population and delineated transition states between early progenitors and a highly heterogeneous ILC1, ILC3, and NK precursor cell cluster.
Tue Jul 16 00:00:00 EDT 2019
Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis.
Journal of virology
Niemeyer BF,Oko LM,Medina EM,Oldenburg DG,White DW,Cool CD,Clambey ET,van Dyk LF
Published figure using CD5 monoclonal antibody (Product # 25-0051-81) in Flow Cytometry
Thu Mar 15 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD5 monoclonal antibody (Product # 25-0051-81) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression.
Molecular cell
Ren G,Jin W,Cui K,Rodrigez J,Hu G,Zhang Z,Larson DR,Zhao K
Published figure using CD5 monoclonal antibody (Product # 25-0051-81) in Flow Cytometry
Thu Sep 21 00:00:00 EDT 2017
Naïve helper T cells with high CD5 expression have increased calcium signaling.
PloS one
Freitas CMT,Hamblin GJ,Raymond CM,Weber KS
Published figure using CD5 monoclonal antibody (Product # 25-0051-81) in Flow Cytometry
Tue Sep 26 00:00:00 EDT 2017
Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms.
Blood
Lykken JM,Horikawa M,Minard-Colin V,Kamata M,Miyagaki T,Poe JC,Tedder TF
25-0051 was used in Flow cytometry/Cell sorting to elucidate the mechanisms through which non-Hodgkin lymphomas initially resist or gain resistance to immunotherapy.
Thu Apr 14 00:00:00 EDT 2016
BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia.
Leukemia
Chen SS,Chang BY,Chang S,Tong T,Ham S,Sherry B,Burger JA,Rai KR,Chiorazzi N
25-0051 was used in Flow cytometry/Cell sorting to identify CXCR4 as a key regulator in BTK-mediated CLL-cell retention.
Fri Apr 01 00:00:00 EDT 2016
IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.
The Journal of investigative dermatology
Rak GD,Osborne LC,Siracusa MC,Kim BS,Wang K,Bayat A,Artis D,Volk SW
25-0051 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous injury promotes an IL-33-dependent group 2 ILC response and that abrogation of this response can impair efficient wound closure.
Mon Feb 01 00:00:00 EST 2016
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
25-0051 was used in Flow cytometry/Cell sorting to indicate a close link between NFATc1 and IL-10 expression in B cells, suggesting that NFATc1 may be a potential target to treat human psoriasis.
Wed May 25 00:00:00 EDT 2016
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD5 monoclonal antibody (Product # 25-0051-81) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Immune targeting of the pleural space by intercostal approach.
BMC pulmonary medicine
Weber GF
25-0051 was used in Flow cytometry/Cell sorting to develop an experimental technique that allows for an in vivo analysis of pleural space immune cells participating in the host defense during airway disease.
Wed Feb 18 00:00:00 EST 2015
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
The Journal of experimental medicine
Weber GF,Chousterman BG,Hilgendorf I,Robbins CS,Theurl I,Gerhardt LM,Iwamoto Y,Quach TD,Ali M,Chen JW,Rothstein TL,Nahrendorf M,Weissleder R,Swirski FK
25-0051 was used in Flow cytometry/Cell sorting to study the migration and release of immunoglobulin M by B1a B cells in response to lung infection.
Mon Jun 02 00:00:00 EDT 2014
Mast cells control the expansion and differentiation of IL-10-competent B cells.
Journal of immunology (Baltimore, Md. : 1950)
Mion F,D'Incà F,Danelli L,Toffoletto B,Guarnotta C,Frossi B,Burocchi A,Rigoni A,Gerdes N,Lutgens E,Tripodo C,Colombo MP,Rivera J,Vitale G,Pucillo CE
25-0051 was used in Flow cytometry/Cell sorting to investigate whether mast cells could play a role in the expansion of IL-10-competent B cells.
Sat Nov 01 00:00:00 EDT 2014
Developmental stage determines efficiency of gene transfer to muscle satellite cells by in utero delivery of adeno-associated virus vector serotype 2/9.
Molecular therapy. Methods & clinical development
Stitelman DH,Brazelton T,Bora A,Traas J,Merianos D,Limberis M,Davey M,Flake AW
25-0051 was used in Flow cytometry/Cell sorting to study the efficiency of gene transfer via adeno-associated virus vector serotype 2/9 to muscle satellite cells at different developmental stages, to show that higher efficiency of transfer occurs at E16 when satellite cells (muscle stem cells) migrate.
Wed May 27 00:00:00 EDT 2015
Type 2 innate lymphoid cells control eosinophil homeostasis.
Nature
Nussbaum JC,Van Dyken SJ,von Moltke J,Cheng LE,Mohapatra A,Molofsky AB,Thornton EE,Krummel MF,Chawla A,Liang HE,Locksley RM
25-0051 was used in Flow cytometry/Cell sorting to investigate the processes underlying regulation of cytokine and chemokines for eosinophil development and survival, showing that type 2 innate lymphoid cells control eosinophil homeostasis.
Thu Oct 10 00:00:00 EDT 2013
CD5-dependent CK2 activation pathway regulates threshold for T cell anergy.
Journal of immunology (Baltimore, Md. : 1950)
Sestero CM,McGuire DJ,De Sarno P,Brantley EC,Soldevila G,Axtell RC,Raman C
25-0051 was used in Flow cytometry/Cell sorting to determine the physiological significance of CD5-dependent casein kinase 2 activation in T cells.
Sat Sep 15 00:00:00 EDT 2012
Induction of IL-10-producing CD1dhighCD5+ regulatory B cells following Babesia microti-infection.
PloS one
Jeong YI,Hong SH,Cho SH,Lee WJ,Lee SE
25-0051 was used in Flow cytometry/Cell sorting to demonstrate the expansion of Bregs following infection by an intraerythrocytic protozoan parasite.
Tue Apr 02 00:00:00 EDT 2013
Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia.
Leukemia
Sanchez-Aguilera A,Rattmann I,Drew DZ,Müller LU,Summey V,Lucas DM,Byrd JC,Croce CM,Gu Y,Cancelas JA,Johnston P,Moritz T,Williams DA
25-0051 was used in Flow cytometry/Cell sorting to investigate the function of RhoH in the B-cell lineage, showing that RhoH is involved in the development of B-cell chronic lymphocytic leukemia.
Fri Jan 01 00:00:00 EST 2010
