Product References
Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.
International journal of nanomedicine
Wang J,Tan Y,Dai Y,Hu K,Tan X,Jiang S,Li G,Zhang X,Kang L,Wang X,Xu B
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Thu Oct 05 00:00:00 EDT 2023
Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.
iScience
Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri Oct 20 00:00:00 EDT 2023
Neutrophil Extracellular Traps Release following Hypoxic-Ischemic Brain Injury in Newborn Rats Treated with Therapeutic Hypothermia.
International journal of molecular sciences
Bernis ME,Zweyer M,Maes E,Schleehuber Y,Sabir H
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri Feb 10 00:00:00 EST 2023
LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.
Journal for immunotherapy of cancer
Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Role of Annexin A1 Secreted by Neutrophils in Melanoma Metastasis.
Cells
Sandri S,Hebeda CB,Broering MF,de Paula Silva M,Moredo LF,de Barros E Silva MJ,Sapata Molina A,Lopes Pinto CA,Duprat Neto JP,Reutelingsperger CP,Gil CD,Farsky SHP
16-9668-82 was used in Immunohistochemistry-immunofluorescence to show that AnxA1 secreted by neutrophils favors melanoma metastasis evolution via FPR pathways, addressing AnxA1 as a potential biomarker for the detection or progression of melanoma.
Fri Jan 27 00:00:00 EST 2023
GPR84 regulates pulmonary inflammation by modulating neutrophil functions.
Acta pharmacologica Sinica
Wang SW,Zhang Q,Lu D,Fang YC,Yan XC,Chen J,Xia ZK,Yuan QT,Chen LH,Zhang YM,Nan FJ,Xie X
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Wed Feb 10 00:00:00 EST 2021
Eliminating mesothelioma by AAV-vectored, PD1-based vaccination in the tumor microenvironment.
Molecular therapy oncolytics
Tan Z,Chiu MS,Yan CW,Man K,Chen Z
16-9668-82 was used in Flow Cytometry to evaluate the potential of recombinant adeno-associated virus (rAAV)-vectored, PD1-based vaccination in the tumor microenvironment (TME) to activate antigen-specific T cell responses in the immune-competent murine mesothelioma model.
Fri Mar 26 00:00:00 EDT 2021
Alterations of macrophage and neutrophil content in skeletal muscle of aged versus young mice.
Muscle & nerve
Kawanishi N,Machida S
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence.
Cell death & disease
Sun SN,Ni SH,Li Y,Liu X,Deng JP,Chen ZX,Li H,Feng WJ,Huang YS,Li DN,Xian SX,Yang ZQ,Wang LJ,Lu L
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology.
Vaccines
DeMarco JK,Royal JM,Severson WE,Gabbard JD,Hume S,Morton J,Swope K,Simpson CA,Shepherd JW,Bratcher B,Palmer KE,Pogue GP
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Wed Nov 17 00:00:00 EST 2021
CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology.
Vaccines
DeMarco JK,Royal JM,Severson WE,Gabbard JD,Hume S,Morton J,Swope K,Simpson CA,Shepherd JW,Bratcher B,Palmer KE,Pogue GP
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Wed Nov 17 00:00:00 EST 2021
CCR2 deficiency alters activation of microglia subsets in traumatic brain injury.
Cell reports
Somebang K,Rudolph J,Imhof I,Li L,Niemi EC,Shigenaga J,Tran H,Gill TM,Lo I,Zabel BA,Schmajuk G,Wipke BT,Gyoneva S,Jandreski L,Craft M,Benedetto G,Plowey ED,Charo I,Campbell J,Ye CJ,Panter SS,Nakamura MC,Eckalbar W,Hsieh CL
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Tue Sep 21 00:00:00 EDT 2021
Actin fence therapy with exogenous V12Rac1 protects against acute lung injury.
JCI insight
Gusarova GA,Das SR,Islam MN,Westphalen K,Jin G,Shmarakov IO,Li L,Bhattacharya S,Bhattacharya J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Mon Mar 22 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity.
Frontiers in immunology
Callejas BE,Blyth GAD,Jendzjowsky N,Wang A,Babbar A,Koro K,Wilson RJA,Kelly MM,Cobo ER,McKay DM
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri Dec 17 00:00:00 EST 2021
Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity.
Frontiers in immunology
Callejas BE,Blyth GAD,Jendzjowsky N,Wang A,Babbar A,Koro K,Wilson RJA,Kelly MM,Cobo ER,McKay DM
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri Dec 17 00:00:00 EST 2021
STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer.
Journal for immunotherapy of cancer
Lee SJ,Yang H,Kim WR,Lee YS,Lee WS,Kong SJ,Lee HJ,Kim JH,Cheon J,Kang B,Chon HJ,Kim C
16-9668-82 was used in Flow Cytometry to elucidate the immune-evasion mechanisms during the peritoneal carcinomatosis of colon cancer and developed a novel immunotherapy by activating the stimulator of interferon genes (STING) pathway.
Tue Jun 01 00:00:00 EDT 2021
Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils.
Nature communications
Manriquez V,Nivoit P,Urbina T,Echenique-Rivera H,Melican K,Fernandez-Gerlinger MP,Flamant P,Schmitt T,Bruneval P,Obino D,Duménil G
16-9668-82 was used in Flow Cytometry to demonstrate how neutrophil recruitment contributes to resolution of Neisseria meningitidis in a humanized mouse model.
Tue Jul 27 00:00:00 EDT 2021
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Local sympathetic innervations modulate the lung innate immune responses.
Science advances
Liu T,Yang L,Han X,Ding X,Li J,Yang J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Local sympathetic innervations modulate the lung innate immune responses.
Science advances
Liu T,Yang L,Han X,Ding X,Li J,Yang J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Local sympathetic innervations modulate the lung innate immune responses.
Science advances
Liu T,Yang L,Han X,Ding X,Li J,Yang J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
A Simple and Effective Flow Cytometry-Based Method for Identification and Quantification of Tissue Infiltrated Leukocyte Subpopulations in a Mouse Model of Peripheral Arterial Disease.
International journal of molecular sciences
Kumaraswami K,Salei N,Beck S,Rambichler S,Kluever AK,Lasch M,Richter L,Schraml BU,Deindl E
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry (PFA fixed)
Tue May 19 00:00:00 EDT 2020
A Simple and Effective Flow Cytometry-Based Method for Identification and Quantification of Tissue Infiltrated Leukocyte Subpopulations in a Mouse Model of Peripheral Arterial Disease.
International journal of molecular sciences
Kumaraswami K,Salei N,Beck S,Rambichler S,Kluever AK,Lasch M,Richter L,Schraml BU,Deindl E
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry (PFA fixed)
Tue May 19 00:00:00 EDT 2020
Neutrophil extracellular traps promote scar formation in post-epidural fibrosis.
NPJ Regenerative medicine
Jin Z,Sun J,Song Z,Chen K,Nicolas YSM,Kc R,Ma Q,Liu J,Zhang M
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri Oct 30 00:00:00 EDT 2020
Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.
Cells
Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Tue Jul 07 00:00:00 EDT 2020
Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection.
Nature microbiology
Rowe SE,Wagner NJ,Li L,Beam JE,Wilkinson AD,Radlinski LC,Zhang Q,Miao EA,Conlon BP
16-9668 was used in Immunohistochemistry to show that macrophages not only fail to efficiently kill phagocytosed Staphylococcus aureus, but also induce tolerance to multiple antibiotics.
Sat Feb 01 00:00:00 EST 2020
Antimesothelioma Immunotherapy by CTLA-4 Blockade Depends on Active PD1-Based TWIST1 Vaccination.
Molecular therapy oncolytics
Tan Z,Chiu MS,Yan CW,Wong YC,Huang H,Man K,Chen Z
16-9668-82 was used in Flow Cytometry to demonstrate that TWIST1, the basic helix-loop-helix transcription factor, was associated with human mesothelioma tumorigenesis and is required for the invasion and metastasis of mesothelioma in the immune-competent murine AB1 model.
Fri Mar 27 00:00:00 EDT 2020
IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A+Foxp3+ Cells During Mucosal Infection and Is Dysregulated With Aging.
Frontiers in immunology
Bhaskaran N,Faddoul F,Paes da Silva A,Jayaraman S,Schneider E,Mamileti P,Weinberg A,Pandiyan P
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection.
Science advances
Park MY,Kim HS,Lee HY,Zabel BA,Bae YS
16-9668-82 was used in Flow Cytometry to find a previously unidentified pathogenic CD11b+Gr-1+ myeloid cell population that expresses stem cell antigen-1 (Sca-1) induced upon experimental infection with Staphylococcus aureus.
Wed Jan 01 00:00:00 EST 2020
Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses.
Science advances
Si Y,Tian Q,Zhao F,Kelly SH,Shores LS,Camacho DF,Sperling AI,Andrade MS,Collier JH,Chong AS
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Cell
Jin C,Lagoudas GK,Zhao C,Bullman S,Bhutkar A,Hu B,Ameh S,Sandel D,Liang XS,Mazzilli S,Whary MT,Meyerson M,Germain R,Blainey PC,Fox JG,Jacks T
16-9668-82 was used in Flow Cytometry to link local microbiota-immune crosstalk to lung tumor development and thereby define key cellular and molecular mediators that may serve as effective targets in lung cancer intervention.
Thu Feb 21 00:00:00 EST 2019
Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Blood
Albeituni S,Verbist KC,Tedrick PE,Tillman H,Picarsic J,Bassett R,Nichols KE
16-9668-82 was used in Flow Cytometry to show that ruxolitinib operates through IFN-γ-dependent and -independent mechanisms to dampen HLH by targeting the deleterious effects of T cells and neutrophils, with the latter representing an unappreciated and understudied cell type that contributes to HLH pathogenesis.
Thu Jul 11 00:00:00 EDT 2019
Neutrophil Extracellular Traps Effectively Control Acute Chikungunya Virus Infection.
Frontiers in immunology
Hiroki CH,Toller-Kawahisa JE,Fumagalli MJ,Colon DF,Figueiredo LTM,Fonseca BALD,Franca RFO,Cunha FQ
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Mon Nov 16 00:00:00 EST 2020
Neutrophil Extracellular Traps Effectively Control Acute Chikungunya Virus Infection.
Frontiers in immunology
Hiroki CH,Toller-Kawahisa JE,Fumagalli MJ,Colon DF,Figueiredo LTM,Fonseca BALD,Franca RFO,Cunha FQ
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Mon Nov 16 00:00:00 EST 2020
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Nature communications
Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
A phospholipase D2 inhibitor, CAY10594, ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.
Scientific reports
Lee SK,Bae GH,Kim YS,Kim HS,Lee M,Ghim J,Zabel BA,Ryu SH,Bae YS
16-9668-82 was used in Flow Cytometry to investigate acetaminophen-induced acute liver injury treatment.
Fri May 10 00:00:00 EDT 2019
Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells.
Journal for immunotherapy of cancer
Gao W,Zhang X,Yang W,Dou D,Zhang H,Tang Y,Zhong W,Meng J,Bai Y,Liu Y,Yang L,Chen S,Liu H,Yang C,Sun T
16-9668-82 was used in Flow Cytometry to investigate if a potential option for enhancing the efficacy of PD-1 inhibitors in clinical applications exists.
Wed Aug 28 00:00:00 EDT 2019
The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism.
Journal of immunology (Baltimore, Md. : 1950)
Fensterheim BA,Young JD,Luan L,Kleinbard RR,Stothers CL,Patil NK,McAtee-Pereira AG,Guo Y,Trenary I,Hernandez A,Fults JB,Williams DL,Sherwood ER,Bohannon JK
16-9668 was used in inhibition assays to demonstrate that MPLA prompts resistance to infection, in part, by inducing a sustained and dynamic metabolic program in macrophages.
Fri Jun 01 00:00:00 EDT 2018
Transformation of Fonsecaea pedrosoi into sclerotic cells links to the refractoriness of experimental chromoblastomycosis in BALB/c mice via a mechanism involving a chitin-induced impairment of IFN-γ production.
PLoS neglected tropical diseases
Dong B,Tong Z,Li R,Chen SC,Liu W,Liu W,Chen Y,Zhang X,Duan Y,Li D,Chen L
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis.
Nature communications
Rayes J,Lax S,Wichaiyo S,Watson SK,Di Y,Lombard S,Grygielska B,Smith SW,Skordilis K,Watson SP
16-9668 was used in Flow cytometry/Cell sorting to demonstrate, through two mouse models of sepsis, the anti-inflammatory role of the podoplanin-CLEC-2 axis.
Thu Dec 21 00:00:00 EST 2017
Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration.
Cell research
Cai Z,Zhang A,Choksi S,Li W,Li T,Zhang XM,Liu ZG
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE.
Basic research in cardiology
Tian Y,Pan D,Chordia MD,French BA,Kron IL,Yang Z
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunofluorescence
Tue Nov 01 00:00:00 EDT 2016
ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.
Frontiers in immunology
Zha QB,Wei HX,Li CG,Liang YD,Xu LH,Bai WJ,Pan H,He XH,Ouyang DY
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Neutrophil recruitment to lymph nodes limits local humoral response to Staphylococcus aureus.
PLoS pathogens
Kamenyeva O,Boularan C,Kabat J,Cheung GY,Cicala C,Yeh AJ,Chan JL,Periasamy S,Otto M,Kehrl JH
16-9668 was used in an ELISA assay to reveal that neutrophils mobilized from bone marrow after a bacterial challenge, dampen the early humoral response in the lymph node.
Wed Apr 01 00:00:00 EDT 2015
