Product References
A human receptor occupancy assay to measure anti-PD-1 binding in patients with prior anti-PD-1.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Junker F,Gulati P,Wessels U,Seeber S,Stubenrauch KG,Codarri-Deak L,Markert C,Klein C,Camillo Teixeira P,Kao H
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages.
Journal of inflammation research
Lai CY,Tseng PC,Chen CL,Satria RD,Wang YT,Lin CF
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Wed Apr 27 00:00:00 EDT 2022
Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation.
Scientific reports
Roberts A,Bentley L,Tang T,Stewart F,Pallini C,Juvvanapudi J,Wallace GR,Cooper AJ,Scott A,Thickett D,Lugg ST,Bancroft H,Hemming B,Ferris C,Langman G,Robinson A,Chapman J,Naidu B,Pinkney T,Taylor GS,Brock K,Stamataki Z,Brady CA,Curnow SJ,Gordon J,Qureshi O,Barnes NM
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Wed Feb 17 00:00:00 EST 2021
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Heliyon
Singh Y,Trautwein C,Fendel R,Krickeberg N,Berezhnoy G,Bissinger R,Ossowski S,Salker MS,Casadei N,Riess O
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Immunopeptidomics-Guided Warehouse Design for Peptide-Based Immunotherapy in Chronic Lymphocytic Leukemia.
Frontiers in immunology
Nelde A,Maringer Y,Bilich T,Salih HR,Roerden M,Heitmann JS,Marcu A,Bauer J,Neidert MC,Denzlinger C,Illerhaus G,Aulitzky WE,Rammensee HG,Walz JS
14-2799-80 was used in ELISA to develop an immunopeptidome-guided workflow for the design of tumor-associated off-the-shelf peptide warehouses for broadly applicable personalized therapeutics.
Mon Dec 20 00:00:00 EST 2021
E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases.
The Journal of clinical investigation
Wang Z,Zhao M,Yin J,Liu L,Hu L,Huang Y,Liu A,Ouyang J,Min X,Rao S,Zhou W,Wu H,Yoshimura A,Lu Q
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Risk-associated alterations in marrow T cells in pediatric leukemia.
JCI insight
Bailur JK,McCachren SS,Pendleton K,Vasquez JC,Lim HS,Duffy A,Doxie DB,Kaushal A,Foster C,DeRyckere D,Castellino S,Kemp ML,Qiu P,Dhodapkar MV,Dhodapkar KM
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Phase I Study of Ficlatuzumab and Cetuximab in Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Cancer.
Cancers
Bauman JE,Ohr J,Gooding WE,Ferris RL,Duvvuri U,Kim S,Johnson JT,Soloff AC,Wallweber G,Winslow J,Gaither-Davis A,Grandis JR,Stabile LP
14-2799-80 was used in Flow Cytometry to establish the recommended Phase II dose (RP2D). Secondary objectives included overall response rate (ORR), progression-free survival (PFS), and overall survival (OS).
Thu Jun 11 00:00:00 EDT 2020
The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.
The Journal of experimental medicine
Hill DL,Pierson W,Bolland DJ,Mkindi C,Carr EJ,Wang J,Houard S,Wingett SW,Audran R,Wallin EF,Jongo SA,Kamaka K,Zand M,Spertini F,Daubenberger C,Corcoran AE,Linterman MA
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Mon Aug 05 00:00:00 EDT 2019
mTORC2 deficiency in cutaneous dendritic cells potentiates CD8+ effector T cell responses and accelerates skin graft rejection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Watson AR,Dai H,Diaz-Perez JA,Killeen ME,Mathers AR,Thomson AW
14-2799-80 was used in Flow Cytometry to suggest that mTORC2 in skin DCs restrains effector CD8+ T cell responses and have implications for understanding of the influence of mTOR inhibitors that target mTORC2 in transplant.
Fri Mar 01 00:00:00 EST 2019
Expression patterns of programmed death-1 and programmed death-1 ligand-1 on T cells in gastric cancer.
Oncology letters
Kim JH,Kim SY,Shin EY,Jung JH,Choi HJ,Jun KH
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Immunohistochemistry
Sun Sep 01 00:00:00 EDT 2019
High PD-L1 Expression Predicts for Worse Outcome of Leukemia Patients with Concomitant NPM1 and FLT3 Mutations.
International journal of molecular sciences
Brodská B,Otevřelová P,Šálek C,Fuchs O,Gašová Z,Kuželová K
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Mon Jun 10 00:00:00 EDT 2019
Characterizing the Role of Monocytes in T Cell Cancer Immunotherapy Using a 3D Microfluidic Model.
Frontiers in immunology
Lee SWL,Adriani G,Ceccarello E,Pavesi A,Tan AT,Bertoletti A,Kamm RD,Wong SC
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Mon Jun 24 00:00:00 EDT 2019
MAdCAM costimulation through Integrin-α4β7 promotes HIV replication.
Mucosal immunology
Nawaz F,Goes LR,Ray JC,Olowojesiku R,Sajani A,Ansari AA,Perrone I,Hiatt J,Van Ryk D,Wei D,Waliszewski M,Soares MA,Jelicic K,Connors M,Migueles SA,Martinelli E,Villinger F,Cicala C,Fauci AS,Arthos J
14-2799 was used in Immunocytochemistry to study the MAdCAM-dependent costimulatory signalling to naive and memory CD4+ T cells following ligation with integrin α4Β7.
Sat Sep 01 00:00:00 EDT 2018
IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.
Nature communications
Belarif L,Mary C,Jacquemont L,Mai HL,Danger R,Hervouet J,Minault D,Thepenier V,Nerrière-Daguin V,Nguyen E,Pengam S,Largy E,Delobel A,Martinet B,Le Bas-Bernardet S,Brouard S,Soulillou JP,Degauque N,Blancho G,Vanhove B,Poirier N
14-2799 was used in Flow cytometry/Cell sorting to investigate the therapeutic efficacy and mechanism of new anti-human IL-7Rα monoclonal antibodies in non-human primates.
Fri Oct 26 00:00:00 EDT 2018
Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression.
Stem cells (Dayton, Ohio)
Davies LC,Heldring N,Kadri N,Le Blanc K
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Optimization of mass cytometry sample cryopreservation after staining.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Sumatoh HR,Teng KW,Cheng Y,Newell EW
14279980 was used in flow cytometry to demonstrate that freezing already-stained samples suspended in 10% DMSO in FBS is practical and efficient way to preserve already-stained samples for mass cytometry assessment
Sun Jan 01 00:00:00 EST 2017
Balancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine.
Clinical and vaccine immunology : CVI
Jensen K,Dela Pena-Ponce MG,Piatak M,Shoemaker R,Oswald K,Jacobs WR,Fennelly G,Lucero C,Mollan KR,Hudgens MG,Amedee A,Kozlowski PA,Estes JD,Lifson JD,Van Rompay KK,Larsen M,De Paris K
14-2799 was used in Flow cytometry/Cell sorting to develop a pediatric combination vaccine to protect the vulnerable infant population against human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) infections.
Sun Jan 01 00:00:00 EST 2017
Analysis of the cross-talk of Epstein-Barr virus-infected B cells with T cells in the marmoset.
Clinical & translational immunology
Dunham J,van Driel N,Eggen BJ,Paul C,'t Hart BA,Laman JD,Kap YS
14-2799-80 was used in Flow Cytometry to examine the ex vivo cross-talk between lymph node mononuclear cells from EAE marmosets and (semi-) autologous EBV-infected B-lymphoblastoid cell lines.
Wed Feb 01 00:00:00 EST 2017
Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Dunham J,Lee LF,van Driel N,Laman JD,Ni I,Zhai W,Tu GH,Lin JC,Bauer J,'t Hart BA,Kap YS
14279980 was used in flow cytometry to test a therapeutic antibody against CD127 in a mouse model of experimental autoimmune encephalomyelitis
Tue Mar 01 00:00:00 EST 2016
Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1.
Journal of immunology (Baltimore, Md. : 1950)
Garcia-Bates TM,Kim E,Concha-Benavente F,Trivedi S,Mailliard RB,Gambotto A,Ferris RL
14279980 was used in flow cytometry to generate adenoviral vaccines that express HPV-16 E6 and E7 epitopes alone or fused with p16 and assess immune responses
Tue Mar 15 00:00:00 EDT 2016
Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Das R,Verma R,Sznol M,Boddupalli CS,Gettinger SN,Kluger H,Callahan M,Wolchok JD,Halaban R,Dhodapkar MV,Dhodapkar KM
14-2799 was used in Flow cytometry/Cell sorting to show that combination blockade of CTLA-4 and PD-1l eads to nonoverlapping changes in gene expression, including proliferation-associated and chemokine genes.
Sun Feb 01 00:00:00 EST 2015
OMIP-025: evaluation of human T- and NK-cell responses including memory and follicular helper phenotype by intracellular cytokine staining.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Moncunill G,Dobaño C,McElrath MJ,De Rosa SC
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100.
Blood
Lee CE,Fulcher DA,Whittle B,Chand R,Fewings N,Field M,Andrews D,Goodnow CC,Cook MC
14-2799 was used in Flow cytometry/Cell sorting to report 3 related individuals with a novel form of severe B-cell deficiency associated with partial persistence of serum immunoglobulin arising from a missense mutation in NFKB2.
Thu Nov 06 00:00:00 EST 2014
A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.
Journal of virology
Van Rompay KK,Hunter Z,Jayashankar K,Peabody J,Montefiori D,LaBranche CC,Keele BF,Jensen K,Abel K,Chackerian B
14-2799 was used in Flow cytometry/Cell sorting to investigate whether prophylactic immunisation of rhesus macaques with a vaccine against CCR5 could prevent or suppress SIV.
Sat Feb 01 00:00:00 EST 2014
Cytokine/Chemokine responses in activated CD4+ and CD8+ T cells isolated from peripheral blood, bone marrow, and axillary lymph nodes during acute simian immunodeficiency virus infection.
Journal of virology
Kenway-Lynch CS,Das A,Lackner AA,Pahar B
14-2799 was used in Flow cytometry/Cell sorting to study CD4(+) and CD8(+) T cell cytokine and chemokine production following simian immunodeficiency virus (SIV) infection.
Fri Aug 01 00:00:00 EDT 2014
Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.
mAbs
Thaventhiran T,Alhumeed N,Yeang HX,Sethu S,Downey JS,Alghanem AF,Olayanju A,Smith EL,Cross MJ,Webb SD,Williams DP,Bristow A,Ball C,Stebbings R,Sathish JG
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Flow Cytometry
Mon Aug 24 00:00:00 EDT 2015
CD20+ B cell depletion alters T cell homing.
Journal of immunology (Baltimore, Md. : 1950)
Kap YS,van Driel N,Laman JD,Tak PP,'t Hart BA
14-2799 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms of CD20 depletion in the treatment of autoimmune inflammatory disorders, showing that CD20+ B cell depletion alters T cell homing.
Thu May 01 00:00:00 EDT 2014
Adoptive TIL transfer in the adjuvant setting for melanoma: long-term patient survival.
Journal of immunology research
Khammari A,Knol AC,Nguyen JM,Bossard C,Denis MG,Pandolfino MC,Quéreux G,Bercegeay S,Dréno B
14-2799 was used in Immunohistochemistry to confirm association of long-term patient survival with the presence of specific TILs and a decrease in Foxp3 expression.
Wed Jan 07 00:00:00 EST 2015
Short communication: HIV+ viremic slow progressors maintain low regulatory T cell numbers in rectal mucosa but exhibit high T cell activation.
AIDS research and human retroviruses
Shaw JM,Hunt PW,Critchfield JW,McConnell DH,Garcia JC,Pollard RB,Somsouk M,Deeks SG,Shacklett BL
14-2799 was used in Flow cytometry/Cell sorting to suggest that the HIV+ viremic slow progressor phenotype is associated with high immune activation but low numbers of mucosal regulatory T-cells.
Tue Jan 01 00:00:00 EST 2013
Trauma patients' elevated tumor necrosis related apoptosis inducing ligand (TRAIL) contributes to increased T cell apoptosis.
Clinical immunology (Orlando, Fla.)
Bandyopadhyay G,Bankey PE,Miller-Graziano CL
14-2799 was used in Flow cytometry/Cell sorting to study the contribution of elevated tumor necrosis related apoptosis inducing ligand (TRAIL) in trauma patients to increased T cell apoptosis.
Mon Oct 01 00:00:00 EDT 2012
Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.
Retrovirology
Van Rompay KK,Trott KA,Jayashankar K,Geng Y,LaBranche CC,Johnson JA,Landucci G,Lipscomb J,Tarara RP,Canfield DR,Heneine W,Forthal DN,Montefiori D,Abel K
14-2799 was used in Flow cytometry/Cell sorting to provide hope for a functional cure of HIV infection via immunotherapeutic strategies that boost antiviral immunity and reduce the need for continuous antiretroviral therapy.
Tue Jul 17 00:00:00 EDT 2012
Tissue biomarkers in melanoma patients treated with TIL.
PloS one
Knol AC,Nguyen JM,Pandolfino MC,Quéreux G,Brocard A,Peuvrel L,Saint-Jean M,Saiagh S,Khammari A,Dréno B
14-2799 was used in Immunohistochemistry to determine differences in the characteristics of TIL populations obtained from an early stage III and a more advanced stage III.
Mon Jun 17 00:00:00 EDT 2013
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy.
BMC cancer
Ghebeh H,Barhoush E,Tulbah A,Elkum N,Al-Tweigeri T,Dermime S
Published figure using CD279 (PD-1) monoclonal antibody (Product # 14-2799-80) in Immunohistochemistry
Sat Feb 23 00:00:00 EST 2008
