Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.
Nature cell biology
Mitchell CA,Verovskaya EV,Calero-Nieto FJ,Olson OC,Swann JW,Wang X,Hérault A,Dellorusso PV,Zhang SY,Svendsen AF,Pietras EM,Bakker ST,Ho TT,Göttgens B,Passegué E
12-0193-82 was used in Flow cytometry/Cell sorting to characterize the inflammatory milieu that drives both niche and haematopoietic remodelling.
Sun Jan 01 00:00:00 EST 2023
Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.
Investigative ophthalmology & visual science
Finburgh EN,Mauduit O,Noguchi T,Bu JJ,Abbas AA,Hakim DF,Bellusci S,Meech R,Makarenkova HP,Afshari NA
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
A single-cell atlas reveals the heterogeneity of meningeal immunity in a mouse model of Methyl CpG binding protein 2 deficiency.
Frontiers in immunology
Li H,Hu M,Huang Z,Wang Y,Xu Y,Deng J,Zhu M,Feng W,Xu X
12-0193-82 was used in Flow cytometry/Cell sorting to provide novel insights into meningeal immunity, which is a less studied aspect of neuroimmune interactions in Mecp2-mutated diseases, and offer an essential resource for comparative analyses and data exploration to better understand the functional role of meningeal immunity in RTT.
Tue Jan 31 00:00:00 EST 2023
High-yield enrichment of mouse small intestine intraepithelial lymphocytes by immunomagnetic depletion of EpCAM+ cells.
STAR protocols
Prakhar P,Gonzalez V,Park JH
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Fri Mar 18 00:00:00 EDT 2022
Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound.
eLife
Roy R,Zayas J,Singh SK,Delgado K,Wood SJ,Mohamed MF,Frausto DM,Albalawi YA,Price TP,Estupinian R,Giurini EF,Kuzel TM,Zloza A,Reiser J,Shafikhani SH
12-0193-82 was used in Flow cytometry/Cell sorting to posit that CCL3 may have therapeutic potential for the treatment of diabetic foot ulcers if it is applied topically after the surgical debridement process which is intended to reset chronic ulcers into acute fresh wounds.
Thu Feb 03 00:00:00 EST 2022
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.
Autophagy
Liu J,Li S,Fei X,Nan X,Shen Y,Xiu H,Cormier SA,Lu C,Guo C,Wang S,Cai Z,Wang P
12-0193-82 was used in Flow cytometry/Cell sorting to demonstrate the central role of PM-induced neutrophil recruitment in promoting lung cancer metastasis.
Sun May 01 00:00:00 EDT 2022
Krüppel-like factor 2 controls IgA plasma cell compartmentalization and IgA responses.
Mucosal immunology
Wittner J,Schulz SR,Steinmetz TD,Berges J,Hauke M,Channell WM,Cunningham AF,Hauser AE,Hutloff A,Mielenz D,Jäck HM,Schuh W
12-0193-82 was used in Flow cytometry/Cell sorting to conclude that KLF2 not only orchestrates the localization of IgA plasma cells by fine-tuning chemokine receptors and adhesion molecules but also controls IgA responses to Salmonella flagellin.
Fri Apr 01 00:00:00 EDT 2022
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Functional human IgA targets a conserved site on malaria sporozoites.
Science translational medicine
Tan J,Cho H,Pholcharee T,Pereira LS,Doumbo S,Doumtabe D,Flynn BJ,Schön A,Kanatani S,Aylor SO,Oyen D,Vistein R,Wang L,Dillon M,Skinner J,Peterson M,Li S,Idris AH,Molina-Cruz A,Zhao M,Olano LR,Lee PJ,Roth A,Sinnis P,Barillas-Mury C,Kayentao K,Ongoiba A,Francica JR,Traore B,Wilson IA,Seder RA,Crompton PD
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Characterization of p190-Bcr-Abl chronic myeloid leukemia reveals specific signaling pathways and therapeutic targets.
Leukemia
Adnan-Awad S,Kim D,Hohtari H,Javarappa KK,Brandstoetter T,Mayer I,Potdar S,Heckman CA,Kytölä S,Porkka K,Doma E,Sexl V,Kankainen M,Mustjoki S
12-0193 was used in Flow cytometry/Cell sorting to provide novel insights into the mechanisms underlying the distinct features of p190Bcr-Abl CML and promising therapeutic targets for this high-risk patient group.
Thu Jul 01 00:00:00 EDT 2021
The gammaherpesvirus 68 viral cyclin facilitates expression of LANA.
PLoS pathogens
Niemeyer BF,Sanford B,Gibson JE,Berger JN,Oko LM,Medina E,Clambey ET,van Dyk LF
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Regulatory B Cells (Bregs) Inhibit Osteoclastogenesis and Play a Potential Role in Ameliorating Ovariectomy-Induced Bone Loss.
Frontiers in immunology
Sapra L,Bhardwaj A,Mishra PK,Garg B,Verma B,Mishra GC,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu Nov 04 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21.
Nature communications
Zotos D,Quast I,Li-Wai-Suen CSN,McKenzie CI,Robinson MJ,Kan A,Smyth GK,Hodgkin PD,Tarlinton DM
12-0193-82 was used in Flow Cytometry to investigate regulation of cell cycle and germinal centres.
Thu Dec 09 00:00:00 EST 2021
Arthritis flares mediated by tissue-resident memory T cells in the joint.
Cell reports
Chang MH,Levescot A,Nelson-Maney N,Blaustein RB,Winden KD,Morris A,Wactor A,Balu S,Grieshaber-Bouyer R,Wei K,Henderson LA,Iwakura Y,Clark RA,Rao DA,Fuhlbrigge RC,Nigrovic PA
12-0193-82 was used in Flow Cytometry to establish long-lived synovial resident memory T cells as a targetable mediator of disease chronicity in autoimmune arthritis.
Tue Oct 26 00:00:00 EDT 2021
Optimized protocol for immunophenotyping of melanoma and tumor-bearing skin from mouse.
STAR protocols
Krisna SS,Goncalves C,Gagnon N,Huang F,Plourde D,Miller WH,Fritz JH,Del Rincon SV
12-0193-82 was used in Flow cytometry/Cell sorting to determine a protocol for mouse skin isolation and immune cell isolation.
Fri Sep 17 00:00:00 EDT 2021
IL-33/ST2 Axis Plays a Protective Effect in Streptococcus pyogenes Infection through Strengthening of the Innate Immunity.
International journal of molecular sciences
Kuo CF,Chen WY,Yu HH,Tsai YH,Chang YC,Chang CP,Tsao N
12-0193-82 was used in Flow Cytometry to examine the effect of the IL-33/ST2 axis on GAS-induced necrotizing fasciitis.
Wed Sep 29 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
Sadik A,Somarribas Patterson LF,Öztürk S,Mohapatra SR,Panitz V,Secker PF,Pfänder P,Loth S,Salem H,Prentzell MT,Berdel B,Iskar M,Faessler E,Reuter F,Kirst I,Kalter V,Foerster KI,Jäger E,Guevara CR,Sobeh M,Hielscher T,Poschet G,Reinhardt A,Hassel JC,Zapatka M,Hahn U,von Deimling A,Hopf C,Schlichting R,Escher BI,Burhenne J,Haefeli WE,Ishaque N,Böhme A,Schäuble S,Thedieck K,Trump S,Seiffert M,Opitz CA
12-0193 was used in Flow cytometry/Cell sorting to show that IL4I1 blockade opens new avenues for cancer therapy.
Thu Sep 03 00:00:00 EDT 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.
PLoS biology
Kobia FM,Preusse K,Dai Q,Weaver N,Hass MR,Chaturvedi P,Stein SJ,Pear WS,Yuan Z,Kovall RA,Kuang Y,Eafergen N,Sprinzak D,Gebelein B,Brunskill EW,Kopan R
12-0193 was used in Flow cytometry/Cell sorting to highlight the role of the environment in malignancy and colitis and is consistent with Notch-dependent anti-parasite immune responses being compromised in Notch dimer-deficient animals.
Thu Oct 01 00:00:00 EDT 2020
Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.
Stem cells international
Zhao AG,Shah K,Freitag J,Cromer B,Sumer H
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2020
Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis.
Frontiers in immunology
Zhou B,Yang W,Li W,He L,Lu L,Zhang L,Liu Z,Wang Y,Chao T,Huang R,Gu Y,Jia T,Liu Q,Tian S,Pierre P,Maeda T,Liang Y,Kong E
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.
PloS one
Parra M,Weitner M,Yang A,Akue A,Liu X,Schmidt T,Allman WR,Akkoyunlu M,Derrick SC
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state.
Nature communications
Kawabe T,Yi J,Kawajiri A,Hilligan K,Fang D,Ishii N,Yamane H,Zhu J,Jankovic D,Kim KS,Trinchieri G,Sher A
12-0193 was used in Flow cytometry/Cell sorting to study whether MP CD4+ T cells are functionally heterogeneous and, if so, what signals specify the differentiation of MP cell subpopulations under homeostatic conditions.
Mon Jul 06 00:00:00 EDT 2020
CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.
Nature communications
Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ
12-0193 was used in Flow cytometry/Cell sorting to demonstrate the stimulatory effect of CD40L-overexpressing CAR T cells on innate and adaptive immune cells, and provide a rationale for using CD40L-overexpressing CAR T cells to improve immunotherapy responses.
Wed Dec 02 00:00:00 EST 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment.
Nature
Calvanese V,Nguyen AT,Bolan TJ,Vavilina A,Su T,Lee LK,Wang Y,Lay FD,Magnusson M,Crooks GM,Kurdistani SK,Mikkola HKA
12-0193 was used in Flow cytometry/Cell sorting to identify MLLT3 (also known as AF9) as a crucial regulator of HSCs that is highly enriched in human fetal, neonatal and adult HSCs, but downregulated in culture.
Sun Dec 01 00:00:00 EST 2019
Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.
Frontiers in immunology
Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Aug 17 00:00:00 EDT 2020
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Scientific reports
Goldstein JM,Valido A,Lewandowski JP,Walker RG,Mills MJ,Messemer KA,Besseling P,Lee KH,Wattrus SJ,Cho M,Lee RT,Wagers AJ
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Dec 09 00:00:00 EST 2019
Mutations in topoisomerase IIβ result in a B cell immunodeficiency.
Nature communications
Broderick L,Yost S,Li D,McGeough MD,Booshehri LM,Guaderrama M,Brydges SD,Kucharova K,Patel NC,Harr M,Hakonarson H,Zackai E,Cowell IG,Austin CA,Hügle B,Gebauer C,Zhang J,Xu X,Wang J,Croker BA,Frazer KA,Putnam CD,Hoffman HM
12-0193-82 was used in Flow Cytometry to identify mutations in type II topoisomerase as a driver of defective proliferation and survival of B2 cells, leading to a B cell immunodeficiency.
Tue Aug 13 00:00:00 EDT 2019
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
12-0193 was used in Flow cytometry/Cell sorting to demonstrate that the clinical use of blocking CCL5 may induce other chemokine signals such as CXCL1-CXCR2 to induce further enhanced hepatic infiltration of neutrophils.
Tue Jun 04 00:00:00 EDT 2019
Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection.
Cell reports
Anderson CK,Reilly EC,Lee AY,Brossay L
12-0193 was used in Flow cytometry/Cell sorting to study compensatory mechanisms in immune responses to viruses when classical T cell immunity has been evaded.
Tue Apr 09 00:00:00 EDT 2019
IGFBP2 promotes immunosuppression associated with its mesenchymal induction and FcγRIIB phosphorylation in glioblastoma.
PloS one
Liu Y,Song C,Shen F,Zhang J,Song SW
12-0193-82 was used in Flow Cytometry to investigate the effect of IGFBP2 on GBM exposed immune cells and its association with the mesenchymal induction, using a syngeneic mouse GBM model, human GBM samples, and cancer-immune cell co-culture experiments.
Thu Apr 02 00:00:00 EDT 2020
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Cancer discovery
Dominguez PM,Ghamlouch H,Rosikiewicz W,Kumar P,Béguelin W,Fontán L,Rivas MA,Pawlikowska P,Armand M,Mouly E,Torres-Martin M,Doane AS,Calvo Fernandez MT,Durant M,Della-Valle V,Teater M,Cimmino L,Droin N,Tadros S,Motanagh S,Shih AH,Rubin MA,Tam W,Aifantis I,Levine RL,Elemento O,Inghirami G,Green MR,Figueroa ME,Bernard OA,Aoufouchi S,Li S,Shaknovich R,Melnick AM
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.
Molecular cell
Ribeiro de Almeida C,Dhir S,Dhir A,Moghaddam AE,Sattentau Q,Meinhart A,Proudfoot NJ
12-0193 was used in Flow cytometry/Cell sorting to provide evidence for how S-region transcripts interconvert between G4 and R-loop structures to promote IgH class switch recombination.
Thu May 17 00:00:00 EDT 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The Role of Allograft Inflammatory Factor-1 in the Effects of Experimental Diabetes on B Cell Functions in the Heart.
Frontiers in cardiovascular medicine
Sarkar A,Shukla SK,Alqatawni A,Kumar A,Addya S,Tsygankov AY,Rafiq K
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Dec 06 00:00:00 EST 2021
Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing.
The American journal of pathology
Prystaz K,Kaiser K,Kovtun A,Haffner-Luntzer M,Fischer V,Rapp AE,Liedert A,Strauss G,Waetzig GH,Rose-John S,Ignatius A
12-0193 was used in Flow cytometry/Cell sorting to study the mechanisms by which IL-6 regulates bone healing.
Thu Feb 01 00:00:00 EST 2018
Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma.
Naunyn-Schmiedeberg's archives of pharmacology
Kaiser K,Prystaz K,Vikman A,Haffner-Luntzer M,Bergdolt S,Strauss G,Waetzig GH,Rose-John S,Ignatius A
12-0193 was used in Flow cytometry/Cell sorting to suggest that selective IL-6 trans-signaling inhibition may have therapeutic potential to treat fracture healing complications in patients with concomitant injuries.
Tue May 01 00:00:00 EDT 2018
In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation.
Stem cell reports
Kauts ML,Rodriguez-Seoane C,Kaimakis P,Mendes SC,Cortés-Lavaud X,Hill U,Dzierzak E
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Jan 09 00:00:00 EST 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Mon Mar 19 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.
JCI insight
Burman A,Kropski JA,Calvi CL,Serezani AP,Pascoalino BD,Han W,Sherrill T,Gleaves L,Lawson WE,Young LR,Blackwell TS,Tanjore H
12-0193 was used in Flow cytometry/Cell sorting to study the role of hypoxia in lung fibrosis.
Thu Aug 23 00:00:00 EDT 2018
Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.
Nature
Da Mesquita S,Louveau A,Vaccari A,Smirnov I,Cornelison RC,Kingsmore KM,Contarino C,Onengut-Gumuscu S,Farber E,Raper D,Viar KE,Powell RD,Baker W,Dabhi N,Bai R,Cao R,Hu S,Rich SS,Munson JM,Lopes MB,Overall CC,Acton ST,Kipnis J
12-0193-82 was used in Flow cytometry/Cell sorting to show that meningeal lymphatic vessels drain macromolecules from the CNS (cerebrospinal and interstitial fluids) into the cervical lymph nodes in mice.
Wed Aug 01 00:00:00 EDT 2018
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells.
Stem cell reports
Kauts ML,De Leo B,Rodríguez-Seoane C,Ronn R,Glykofrydis F,Maglitto A,Kaimakis P,Basi M,Taylor H,Forrester L,Wilkinson AC,Göttgens B,Saunders P,Dzierzak E
12-0193 was used in Flow cytometry/Cell sorting to demonstrate a method for the rapid/robust production of mast cells from pluripotent stem cells.
Tue Oct 09 00:00:00 EDT 2018
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
12-0193 was used in Flow cytometry/Cell sorting to show that in leukaemia, GMP clusters are constantly produced due to lack of termination cytokines that restore haematopoietic stem-cell quiescence.
Thu Apr 06 00:00:00 EDT 2017
Autophagy maintains the metabolism and function of young and old stem cells.
Nature
Ho TT,Warr MR,Adelman ER,Lansinger OM,Flach J,Verovskaya EV,Figueroa ME,Passegué E
12-0193 was used in Flow cytometry/Cell sorting to demonstrate an essential function for autophagy in removing activated mitochondria and controlling oxidative metabolism, thereby maintaining HSC stemness and regenerative potential.
Thu Mar 09 00:00:00 EST 2017
Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.
Immunity
Dalmas E,Lehmann FM,Dror E,Wueest S,Thienel C,Borsigova M,Stawiski M,Traunecker E,Lucchini FC,Dapito DH,Kallert SM,Guigas B,Pattou F,Kerr-Conte J,Maechler P,Girard JP,Konrad D,Wolfrum C,Böni-Schnetzler M,Finke D,Donath MY
12-0193 was used in Flow cytometry/Cell sorting to provide evidence that an immunometabolic crosstalk between islet-derived IL-33, ILC2s, and myeloid cells fosters insulin secretion.
Tue Nov 21 00:00:00 EST 2017
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo.
Cancer cell
Leanza L,Romio M,Becker KA,Azzolini M,Trentin L,Managò A,Venturini E,Zaccagnino A,Mattarei A,Carraretto L,Urbani A,Kadow S,Biasutto L,Martini V,Severin F,Peruzzo R,Trimarco V,Egberts JH,Hauser C,Visentin A,Semenzato G,Kalthoff H,Zoratti M,Gulbins E,Paradisi C,Szabo I
12-0193 was used in Flow cytometry/Cell sorting to demonstrate that specific pharmacological targeting of a mitochondrial potassium channel can lead to reactive oxygen species-mediated selective apoptosis of cancer cells in vivo, without significant side effects.
Mon Apr 10 00:00:00 EDT 2017
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.
The Journal of clinical investigation
Chang AY,Dao T,Gejman RS,Jarvis CA,Scott A,Dubrovsky L,Mathias MD,Korontsvit T,Zakhaleva V,Curcio M,Hendrickson RC,Liu C,Scheinberg DA
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Fri Jun 30 00:00:00 EDT 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Adenoviral production of interleukin-2 at the tumor site removes the need for systemic postconditioning in adoptive cell therapy.
International journal of cancer
Santos JM,Havunen R,Siurala M,Cervera-Carrascon V,Tähtinen S,Sorsa S,Anttila M,Karell P,Kanerva A,Hemminki A
12-0193-82 was used in Flow Cytometry to study the efficacy and safety of intratumorally administered IL-2 coding adenoviruses in combination with lymphocyte therapy in Syrian hamsters bearing pancreatic tumours.
Sun Oct 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Wagner JM,Jaurich H,Wallner C,Abraham S,Becerikli M,Dadras M,Harati K,Duhan V,Khairnar V,Lehnhardt M,Behr B
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy.
Oncoimmunology
Zafar S,Parviainen S,Siurala M,Hemminki O,Havunen R,Tähtinen S,Bramante S,Vassilev L,Wang H,Lieber A,Hemmi S,de Gruijl T,Kanerva A,Hemminki A
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Protein Tyrosine Phosphatase Inhibition Prevents Experimental Cerebral Malaria by Precluding CXCR3 Expression on T Cells.
Scientific reports
Van Den Ham KM,Smith LK,Richer MJ,Olivier M
12-0193 was used in Flow cytometry/Cell sorting to demonstrate that inhibition of protein tyrosine phosphatase activity significantly attenuates T cell sequestration within the brain and prevents the development of neuropathology.
Fri Jul 14 00:00:00 EDT 2017
The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue.
Nature microbiology
Grau KR,Roth AN,Zhu S,Hernandez A,Colliou N,DiVita BB,Philip DT,Riffe C,Giasson B,Wallet SM,Mohamadzadeh M,Karst SM
12-0193 was used in Flow cytometry/Cell sorting to analyse in vivo norovirus cell tropism in orally inoculated, immunocompetent hosts at the peak of acute infection.
Fri Dec 01 00:00:00 EST 2017
In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.
Particle and fibre toxicology
Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA
12-0193 was used in Flow cytometry/Cell sorting to suggest that Langerhans cells can engulf quantum dots in skin, but lymph node transport is both cellular and non-cellular.
Fri Apr 14 00:00:00 EDT 2017
The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.
Cancer cell
Townsend EC,Murakami MA,Christodoulou A,Christie AL,Köster J,DeSouza TA,Morgan EA,Kallgren SP,Liu H,Wu SC,Plana O,Montero J,Stevenson KE,Rao P,Vadhi R,Andreeff M,Armand P,Ballen KK,Barzaghi-Rinaudo P,Cahill S,Clark RA,Cooke VG,Davids MS,DeAngelo DJ,Dorfman DM,Eaton H,Ebert BL,Etchin J,Firestone B,Fisher DC,Freedman AS,Galinsky IA,Gao H,Garcia JS,Garnache-Ottou F,Graubert TA,Gutierrez A,Halilovic E,Harris MH,Herbert ZT,Horwitz SM,Inghirami G,Intlekofer AM,Ito M,Izraeli S,Jacobsen ED,Jacobson CA,Jeay S,Jeremias I,Kelliher MA,Koch R,Konopleva M,Kopp N,Kornblau SM,Kung AL,Kupper TS,LeBoeuf NR,LaCasce AS,Lees E,Li LS,Look AT,Murakami M,Muschen M,Neuberg D,Ng SY,Odejide OO,Orkin SH,Paquette RR,Place AE,Roderick JE,Ryan JA,Sallan SE,Shoji B,Silverman LB,Soiffer RJ,Steensma DP,Stegmaier K,Stone RM,Tamburini J,Thorner AR,van Hummelen P,Wadleigh M,Wiesmann M,Weng AP,Wuerthner JU,Williams DA,Wollison BM,Lane AA,Letai A,Bertagnolli MM,Ritz J,Brown M,Long H,Aster JC,Shipp MA,Griffin JD,Weinstock DM
12-0193 was used in Flow cytometry/Cell sorting to demonstrate how large studies of acute leukaemia patient-derived xenografts in mice may mimic human randomised clinical trials.
Mon Apr 11 00:00:00 EDT 2016
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.
Cancer discovery
Pylayeva-Gupta Y,Das S,Handler JS,Hajdu CH,Coffre M,Koralov SB,Bar-Sagi D
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Nature cell biology
Dou DR,Calvanese V,Sierra MI,Nguyen AT,Minasian A,Saarikoski P,Sasidharan R,Ramirez CM,Zack JA,Crooks GM,Galic Z,Mikkola HK
12019382 was used in flow cytometry to study how retinoic acid-induced HOXA gene expression controls hematopoietic stem/progenitor cells fate, identify, and function
Wed Jun 01 00:00:00 EDT 2016
Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Nature cell biology
Dou DR,Calvanese V,Sierra MI,Nguyen AT,Minasian A,Saarikoski P,Sasidharan R,Ramirez CM,Zack JA,Crooks GM,Galic Z,Mikkola HK
12019382 was used in flow cytometry to study how retinoic acid-induced HOXA gene expression controls hematopoietic stem/progenitor cells fate, identify, and function
Wed Jun 01 00:00:00 EDT 2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Nature cell biology
Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E
12-0193 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.
Wed Jun 01 00:00:00 EDT 2016
NLRP2 controls age-associated maternal fertility.
The Journal of experimental medicine
Kuchmiy AA,D'Hont J,Hochepied T,Lamkanfi M
12-0193 was used in Flow cytometry/Cell sorting to identify Nlrp2 as a critical regulator of oocyte quality.
Mon Dec 12 00:00:00 EST 2016
Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites.
The Journal of experimental medicine
Wan X,Thomas JW,Unanue ER
12-0193 was used in Flow cytometry/Cell sorting to investigate the interactions of insulin-specific T and B lymphocytes using T cell and B cell receptor transgenic mice.
Mon May 30 00:00:00 EDT 2016
Peptidoglycan-linked protein A promotes T cell-dependent antibody expansion during Staphylococcus aureus infection.
Proceedings of the National Academy of Sciences of the United States of America
Kim HK,Falugi F,Missiakas DM,Schneewind O
12-0193 was used in Flow cytometry/Cell sorting to suggest that staphylococcal protein A cross-linking of VH3 idiotype BCRs and activation via attached peptidoglycan are determinants of staphylococcal escape from adaptive immune responses.
Tue May 17 00:00:00 EDT 2016
Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice.
Disease models & mechanisms
Gil VS,Bhagat G,Howell L,Zhang J,Kim CH,Stengel S,Vega F,Zelent A,Petrie K
12-0193 was used in Flow cytometry/Cell sorting to study the role of HDAC9 in lymphomagenesis.
Thu Dec 01 00:00:00 EST 2016
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Grodeland G,Fredriksen AB,Løset GÅ,Vikse E,Fugger L,Bogen B
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function.
Journal of immunology (Baltimore, Md. : 1950)
Levit-Zerdoun E,Becker M,Pohlmeyer R,Wilhelm I,Maity PC,Rajewsky K,Reth M,Hobeika E
12-0193 was used in Flow cytometry/Cell sorting to assess the importance of the expression of a functional B-cell receptor for B cell maintenance.
Tue Mar 01 00:00:00 EST 2016
IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require α4β1 Integrin To Migrate between the Peritoneum and Inflamed Skin.
Journal of immunology (Baltimore, Md. : 1950)
Geherin SA,Gómez D,Glabman RA,Ruthel G,Hamann A,Debes GF
12-0193 was used in Flow cytometry/Cell sorting to investigate innate-like B cells within the skin.
Tue Mar 15 00:00:00 EDT 2016
Protein Translation Activity: A New Measure of Host Immune Cell Activation.
Journal of immunology (Baltimore, Md. : 1950)
Seedhom MO,Hickman HD,Wei J,David A,Yewdell JW
12-0193 was used in Flow cytometry/Cell sorting to describe the in vivo ribopuromycylation method.
Mon Aug 15 00:00:00 EDT 2016
Helios Controls a Limited Subset of Regulatory T Cell Functions.
Journal of immunology (Baltimore, Md. : 1950)
Sebastian M,Lopez-Ocasio M,Metidji A,Rieder SA,Shevach EM,Thornton AM
12-0193 was used in Flow cytometry/Cell sorting to determine the beneficial effects of the transcription factor, Helios, for Treg maintenance, differentiation, and survival.
Fri Jan 01 00:00:00 EST 2016
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Jul 27 00:00:00 EDT 2016
Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.
Oncotarget
Weiss JM,Robinet M,Aricha R,Cufi P,Villeret B,Lantner F,Shachar I,Fuchs S,Souroujon MC,Berrih-Aknin S,Le Panse R
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.
PloS one
Jonas BA,Johnson C,Gratzinger D,Majeti R
12-0193 was used in Flow cytometry/Cell sorting to report several new t-AML/MDS mouse models that could potentially be used to further define disease pathogenesis and test novel therapeutics.
Wed Jul 26 00:00:00 EDT 2017
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Role of caveolin-3 in lymphocyte activation.
Life sciences
Tran C,Stary CM,Schilling JM,Bentley B,Patel HH,Roth DM
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Thu Jan 15 00:00:00 EST 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Frizzled-6 Regulates Hematopoietic Stem/Progenitor Cell Survival and Self-Renewal.
Journal of immunology (Baltimore, Md. : 1950)
Abidin BM,Owusu Kwarteng E,Heinonen KM
12-0193 was used in Flow cytometry/Cell sorting to reveal that Fzd6 has an essential role in HSPC maintenance and survival.
Tue Sep 01 00:00:00 EDT 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
12-0193 was used in Flow cytometry/Cell sorting to alter the tumor microenvironment using immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
Thu Apr 28 00:00:00 EDT 2016
Expression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic Mice.
PloS one
Yong CS,Westwood JA,Schröder J,Papenfuss AT,von Scheidt B,Moeller M,Devaud C,Darcy PK,Kershaw MH
12-0193 was used in Flow cytometry/Cell sorting to generate a mouse model expressing chimeric antigen receptors (CARs) specific for a tumour antigen under a pan-hematopoietic promoter.
Wed Jun 08 00:00:00 EDT 2016
Identification of a unique TGF-β-dependent molecular and functional signature in microglia.
Nature neuroscience
Butovsky O,Jedrychowski MP,Moore CS,Cialic R,Lanser AJ,Gabriely G,Koeglsperger T,Dake B,Wu PM,Doykan CE,Fanek Z,Liu L,Chen Z,Rothstein JD,Ransohoff RM,Gygi SP,Antel JP,Weiner HL
12-0193 was used in Flow cytometry/Cell sorting to study gene expression in microglia versus myeloid and other immune cells.
Wed Jan 01 00:00:00 EST 2014
Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation.
The Journal of clinical investigation
Li J,Razumilava N,Gores GJ,Walters S,Mizuochi T,Mourya R,Bessho K,Wang YH,Glaser SS,Shivakumar P,Bezerra JA
12-0193 was used in Flow cytometry/Cell sorting to demonstrate the role of the Th2-promoting cytokine, IL-33, in cholangiocyte proliferation.
Tue Jul 01 00:00:00 EDT 2014
Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis.
Science translational medicine
Fletcher AL,Elman JS,Astarita J,Murray R,Saeidi N,D'Rozario J,Knoblich K,Brown FD,Schildberg FA,Nieves JM,Heng TS,Boyd RL,Turley SJ,Parekkadan B
12-0193 was used in Flow cytometry/Cell sorting to characterise a novel population of immune-specialised myofibroblasts derived from lymph node tissue, termed fibroblastic reticular cells.
Wed Aug 13 00:00:00 EDT 2014
Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodies.
mAbs
Marschall AL,Single FN,Schlarmann K,Bosio A,Strebe N,van den Heuvel J,Frenzel A,Dübel S
12-0193 was used in Flow cytometry/Cell sorting to investigate the use of ER intrabodies to knock-down protein expression.
Tue Sep 01 00:00:00 EDT 2015
CD40 ligand preferentially modulates immune response and enhances protection against influenza virus.
Journal of immunology (Baltimore, Md. : 1950)
Hashem AM,Gravel C,Chen Z,Yi Y,Tocchi M,Jaentschke B,Fan X,Li C,Rosu-Myles M,Pereboev A,He R,Wang J,Li X
12-0193 was used in Flow cytometry/Cell sorting to characterise an increased in vivo load of CD40-targeted Ag upon the secretion of the NP-CD40L fusion protein from adenovirus-infected cells.
Tue Jul 15 00:00:00 EDT 2014
Oral combined therapy with probiotics and alloantigen induces B cell-dependent long-lasting specific tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Mercadante AC,Perobelli SM,Alves AP,Gonçalves-Silva T,Mello W,Gomes-Santos AC,Miyoshi A,Azevedo V,Faria AM,Bonomo A
12-0193 was used in Flow cytometry/Cell sorting to suggest that combined therapy is a promising strategy for prevention of GVHD with preservation of graft-versus-leukemia in allogenic HSCT.
Sat Feb 15 00:00:00 EST 2014
Generation of a novel Cr2 gene allele by homologous recombination that abrogates production of Cr2 but is sufficient for expression of Cr1.
Immunobiology
Donius LR,Orlando CM,Weis JJ,Weis JH
12-0193 was used in Flow cytometry/Cell sorting to study how the Cr2KO mouse provides a new model system for the analysis of Cr1 and Cr2 functions in the immune response of the mouse.
Wed Jan 01 00:00:00 EST 2014
A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors.
The Journal of experimental medicine
Chen YL,Chen TT,Pai LM,Wesoly J,Bluyssen HA,Lee CK
12-0193 was used in Flow cytometry/Cell sorting to define a critical role for the FL/IFN-I/Flt3 axis in plasmacytoid dendritic cell differentiation from common lymphoid progenitors.
Mon Nov 18 00:00:00 EST 2013
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
12-0193 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 EDT 2013
Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
Journal of immunology (Baltimore, Md. : 1950)
Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT
12-0193 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.
Sun Dec 01 00:00:00 EST 2013
CD4+ CD25+ FOXP3+ Treg cells induced by rSSP4 derived from T. cruzi amastigotes increase parasitemia in an experimental Chagas disease model.
BioMed research international
Flores-García Y,Rosales-Encina JL,Rosales-García VH,Satoskar AR,Talamás-Rohana P
12-0193 was used in Flow cytometry/Cell sorting to examine the degree of benefit conferred by Treg cells during T.cruzi infection.
Tue Nov 12 00:00:00 EST 2013
Transcription factor RORα is critical for nuocyte development.
Nature immunology
Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN
12-0193 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.
Sun Jan 22 00:00:00 EST 2012
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
12-0193 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2012
A TLR and non-TLR mediated innate response to lentiviruses restricts hepatocyte entry and can be ameliorated by pharmacological blockade.
Molecular therapy : the journal of the American Society of Gene Therapy
Agudo J,Ruzo A,Kitur K,Sachidanandam R,Blander JM,Brown BD
12-0193 was used in Flow cytometry/Cell sorting to characterise the transient innate immune reaction to lentiviral vector, and evaluate a means for its prevention during LV-mediated gene transfer.
Sat Dec 01 00:00:00 EST 2012
Overexpression of Snai3 suppresses lymphoid- and enhances myeloid-cell differentiation.
European journal of immunology
Dahlem T,Cho S,Spangrude GJ,Weis JJ,Weis JH
12-0193 was used in Flow cytometry/Cell sorting to investigate the role of the transcriptional repressor Snai3 protein in the derivation of cells of the haematopoietic system.
Sun Apr 01 00:00:00 EDT 2012
Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease.
The American journal of pathology
Szczepanek SM,McNamara JT,Secor ER,Natarajan P,Guernsey LA,Miller LA,Ballesteros E,Jellison E,Thrall RS,Andemariam B
12-0193 was used in Flow cytometry/Cell sorting to investigate the relationship between functional asplenia from infarctions and increased infectious mortality in a mouse model of sickle-cell disease.
Thu Nov 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD19 monoclonal antibody (Product # 12-0193-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties.
Journal of immunology (Baltimore, Md. : 1950)
Kerzerho J,Yu ED,Barra CM,Alari-Pahissa E,Girardi E,Harrak Y,Lauzurica P,Llebaria A,Zajonc DM,Akbari O,Castaño AR
12-0193 was used in Flow cytometry/Cell sorting to assess the potential for the use of HS44 as a reagent for immune manipulation.
Thu Mar 01 00:00:00 EST 2012
Mouse β-defensin 14 (Defb14) promotes tumor growth by inducing angiogenesis in a CCR6-dependent manner.
Journal of immunology (Baltimore, Md. : 1950)
Röhrl J,Huber B,Koehl GE,Geissler EK,Hehlgans T
12-0193 was used in Flow cytometry/Cell sorting to analyse the expression of mBD14 in cultured mice fibrosarcoma tumour cells and its effect on tumour growth.
Tue May 15 00:00:00 EDT 2012
Human papillomavirus immunization is associated with increased expression of different innate immune regulatory receptors.
Clinical and vaccine immunology : CVI
Colmenares V,Noyola DE,Monsiváis-Urenda A,Salgado-Bustamante M,Estrada-Capetillo L,González-Amaro R,Baranda L
12-0193 was used in Flow cytometry/Cell sorting to study how HPV immunisation alters innate immune receptor function as part of its protective effect.
Sun Jul 01 00:00:00 EDT 2012
Impact of enzymatic tissue disintegration on the level of surface molecule expression and immune cell function.
European journal of microbiology & immunology
Autengruber A,Gereke M,Hansen G,Hennig C,Bruder D
12-0193 was used in Flow cytometry/Cell sorting to indicate that enzymatic tissue disintegration can have profound effects on the expression of a variety of cell-surface molecules.
Fri Jun 01 00:00:00 EDT 2012
RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells.
Immunity
Powolny-Budnicka I,Riemann M,Tänzer S,Schmid RM,Hehlgans T,Weih F
12-0193 was used in Flow cytometry/Cell sorting to investigate the contribution of NF-κB to IL-17 production by T cells, showing that RelA and RelB in distinct thymocyte populations control lymphotoxin-dependent IL-17 production.
Fri Mar 25 00:00:00 EDT 2011
Deletion of genes encoding PU.1 and Spi-B in B cells impairs differentiation and induces pre-B cell acute lymphoblastic leukemia.
Blood
Sokalski KM,Li SK,Welch I,Cadieux-Pitre HA,Gruca MR,DeKoter RP
12-0193 was used in Flow cytometry/Cell sorting to investigate the impairment of differentiation of B cells and induction of pre-B cell acute lymphoblastic leukemia through the deletion of genes encoding PU.1 and Spi-1 in B cells.
Thu Sep 08 00:00:00 EDT 2011
Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype.
The Journal of clinical investigation
Li J,Bessho K,Shivakumar P,Mourya R,Mohanty SK,Dos Santos JL,Miura IK,Porta G,Bezerra JA
12-0193 was used in Flow cytometry/Cell sorting to assess whether Th1-independent mechanisms can activate effector cells to induce biliary atresia.
Tue Nov 01 00:00:00 EDT 2011
Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape.
Journal of immunology (Baltimore, Md. : 1950)
Duong BH,Ota T,Aoki-Ota M,Cooper AB,Ait-Azzouzene D,Vela JL,Gavin AL,Nemazee D
12-0193 was used in Flow cytometry/Cell sorting to demonstrate the usefulness of reconstituted IgM(b) superantigen hosts in revealing pathways involved in central tolerance.
Thu Dec 01 00:00:00 EST 2011
Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells.
Journal of cell science
Meziane el K,Randle SJ,Nelson DE,Lomonosov M,Laman H
12-0193 was used in Flow cytometry/Cell sorting to test the ability of Fbxo7 to transform haematopoietic pro-B cells.
Fri Jul 01 00:00:00 EDT 2011
The outcome of polymicrobial sepsis is independent of T and B cells.
Shock (Augusta, Ga.)
Bosmann M,Russkamp NF,Patel VR,Zetoune FS,Sarma JV,Ward PA
12-0193 was used in Flow cytometry/Cell sorting to use mice lacking the recombination activating gene 1 (Rag-1) to study the role of T and B cells in sepsis after cecal ligation and puncture (CLP).
Sat Oct 01 00:00:00 EDT 2011
Th17 cells are involved in the local control of tumor progression in primary intraocular lymphoma.
PloS one
Galand C,Donnou S,Crozet L,Brunet S,Touitou V,Ouakrim H,Fridman WH,Sautès-Fridman C,Fisson S
12-0193 was used in Flow cytometry/Cell sorting to study how Th17 cells or their related cytokines could be considered to be a new therapeutic approach for non-Hodgkin B-cell lymphomas.
Fri Feb 03 00:00:00 EST 2012
Basophils support the survival of plasma cells in mice.
Journal of immunology (Baltimore, Md. : 1950)
Rodriguez Gomez M,Talke Y,Goebel N,Hermann F,Reich B,Mack M
12-0193 was used in Flow cytometry/Cell sorting to investigate whether basophils support plasma cell survival and Ig production.
Wed Dec 15 00:00:00 EST 2010
BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Smith IA,Knezevic BR,Ammann JU,Rhodes DA,Aw D,Palmer DB,Mather IH,Trowsdale J
12-0193 was used in Flow cytometry/Cell sorting to confirm a coinhibitory role for mouse BTN1A1.
Thu Apr 01 00:00:00 EDT 2010
Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C.
Journal of immunology (Baltimore, Md. : 1950)
DeKoter RP,Geadah M,Khoosal S,Xu LS,Thillainadesan G,Torchia J,Chin SS,Garrett-Sinha LA
12-0193 was used in Flow cytometry/Cell sorting to demonstrate the role of the E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C in follicular B cell development.
Wed Dec 15 00:00:00 EST 2010
Treatment with LL-37 peptide enhances antitumor effects induced by CpG oligodeoxynucleotides against ovarian cancer.
Human gene therapy
Chuang CM,Monie A,Wu A,Mao CP,Hung CF
12-0193 was used in Flow cytometry/Cell sorting to demonstrate the potential of combined CpG-ODN-LL-37 peptide treatment for the control of ovarian tumours.
Wed Apr 01 00:00:00 EDT 2009
Some putative prebiotics increase the severity of Salmonella enterica serovar Typhimurium infection in mice.
BMC microbiology
Petersen A,Heegaard PM,Pedersen AL,Andersen JB,Sørensen RB,Frøkiaer H,Lahtinen SJ,Ouwehand AC,Poulsen M,Licht TR
12-0193 was used in Flow cytometry/Cell sorting to examine whether Salmonella infection could be prevented by administration of dietary carbohydrates with different structures and digestibility profiles.
Mon Nov 30 00:00:00 EST 2009
miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely.
Proceedings of the National Academy of Sciences of the United States of America
Zhou B,Wang S,Mayr C,Bartel DP,Lodish HF
12-0193 was used in Immunofluorescence to study how miR-150 can down-regulate mRNAs important for B cell function, and how it can block further B cell development when expressed prematurely.
Tue Apr 24 00:00:00 EDT 2007
